The Role of Microenvironment in Axonal Regeneration: Influences of Lesion-Induced Changes and Glial Implants on the Regeneration of the Postcommissural Fornix
Since the pioneering studies of Ramon y Cajal the inability of lesioned adult CNS axons to regenerate has been well established. During the past years advancements in molecular, cellular and biochemical knowledge have provided new insights into the extrinsic mechanims underlying regeneration failure...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Berlin, Heidelberg
Springer Berlin Heidelberg
1997
|
| Schriftenreihe: | Advances in Anatomy, Embryology and Cell Biology
137 |
| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | Since the pioneering studies of Ramon y Cajal the inability of lesioned adult CNS axons to regenerate has been well established. During the past years advancements in molecular, cellular and biochemical knowledge have provided new insights into the extrinsic mechanims underlying regeneration failure. The rapid progress in this field has already led to the development of new concepts for therapeutic manipulations. This book provides a comprehensive overview of structural and molecular changes induced by an invasive CNS lesion and their involvements in regeneration processes. Moreover, it demonstrates the strong growth-promoting actitivies of implanted glial cells. The data is discussed in relation to current knowledge on the mechanisms of axonal degeneration and regeneration and in terms of their relevance for the development of novel therapeutic strategies |
| Beschreibung: | 1 Online-Ressource (VIII, 82 p. 18 illus) |
| ISBN: | 9783642607813 |
| DOI: | 10.1007/978-3-642-60781-3 |
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Datensatz im Suchindex
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| any_adam_object | |
| author | Stichel-Gunkel, Christine C. |
| author_facet | Stichel-Gunkel, Christine C. |
| author_role | aut |
| author_sort | Stichel-Gunkel, Christine C. |
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| building | Verbundindex |
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| dewey-full | 612.8 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 612 - Human physiology |
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| dewey-search | 612.8 |
| dewey-sort | 3612.8 |
| dewey-tens | 610 - Medicine and health |
| discipline | Biologie Medizin |
| doi_str_mv | 10.1007/978-3-642-60781-3 |
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| id | DE-604.BV046144258 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:25Z |
| institution | BVB |
| isbn | 9783642607813 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-031524443 |
| oclc_num | 1119076173 |
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| physical | 1 Online-Ressource (VIII, 82 p. 18 illus) |
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| publishDate | 1997 |
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| publisher | Springer Berlin Heidelberg |
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| series2 | Advances in Anatomy, Embryology and Cell Biology |
| spelling | Stichel-Gunkel, Christine C. Verfasser aut The Role of Microenvironment in Axonal Regeneration Influences of Lesion-Induced Changes and Glial Implants on the Regeneration of the Postcommissural Fornix by Christine C. Stichel-Gunkel Berlin, Heidelberg Springer Berlin Heidelberg 1997 1 Online-Ressource (VIII, 82 p. 18 illus) txt rdacontent c rdamedia cr rdacarrier Advances in Anatomy, Embryology and Cell Biology 137 Since the pioneering studies of Ramon y Cajal the inability of lesioned adult CNS axons to regenerate has been well established. During the past years advancements in molecular, cellular and biochemical knowledge have provided new insights into the extrinsic mechanims underlying regeneration failure. The rapid progress in this field has already led to the development of new concepts for therapeutic manipulations. This book provides a comprehensive overview of structural and molecular changes induced by an invasive CNS lesion and their involvements in regeneration processes. Moreover, it demonstrates the strong growth-promoting actitivies of implanted glial cells. The data is discussed in relation to current knowledge on the mechanisms of axonal degeneration and regeneration and in terms of their relevance for the development of novel therapeutic strategies Neurosciences Animal Physiology Animal physiology Gliazelle (DE-588)4136721-2 gnd rswk-swf Implantation (DE-588)4026660-6 gnd rswk-swf Nervenregeneration (DE-588)4041641-0 gnd rswk-swf Nervenverletzung (DE-588)4041648-3 gnd rswk-swf Extrazellulärraum (DE-588)4205506-4 gnd rswk-swf Tiermodell (DE-588)4140660-6 gnd rswk-swf Axon (DE-588)4200576-0 gnd rswk-swf Axon (DE-588)4200576-0 s Nervenregeneration (DE-588)4041641-0 s Gliazelle (DE-588)4136721-2 s Implantation (DE-588)4026660-6 s Tiermodell (DE-588)4140660-6 s DE-604 Nervenverletzung (DE-588)4041648-3 s Extrazellulärraum (DE-588)4205506-4 s Erscheint auch als Druck-Ausgabe 9783540627876 Erscheint auch als Druck-Ausgabe 9783642607820 https://doi.org/10.1007/978-3-642-60781-3 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Stichel-Gunkel, Christine C. The Role of Microenvironment in Axonal Regeneration Influences of Lesion-Induced Changes and Glial Implants on the Regeneration of the Postcommissural Fornix Neurosciences Animal Physiology Animal physiology Gliazelle (DE-588)4136721-2 gnd Implantation (DE-588)4026660-6 gnd Nervenregeneration (DE-588)4041641-0 gnd Nervenverletzung (DE-588)4041648-3 gnd Extrazellulärraum (DE-588)4205506-4 gnd Tiermodell (DE-588)4140660-6 gnd Axon (DE-588)4200576-0 gnd |
| subject_GND | (DE-588)4136721-2 (DE-588)4026660-6 (DE-588)4041641-0 (DE-588)4041648-3 (DE-588)4205506-4 (DE-588)4140660-6 (DE-588)4200576-0 |
| title | The Role of Microenvironment in Axonal Regeneration Influences of Lesion-Induced Changes and Glial Implants on the Regeneration of the Postcommissural Fornix |
| title_auth | The Role of Microenvironment in Axonal Regeneration Influences of Lesion-Induced Changes and Glial Implants on the Regeneration of the Postcommissural Fornix |
| title_exact_search | The Role of Microenvironment in Axonal Regeneration Influences of Lesion-Induced Changes and Glial Implants on the Regeneration of the Postcommissural Fornix |
| title_full | The Role of Microenvironment in Axonal Regeneration Influences of Lesion-Induced Changes and Glial Implants on the Regeneration of the Postcommissural Fornix by Christine C. Stichel-Gunkel |
| title_fullStr | The Role of Microenvironment in Axonal Regeneration Influences of Lesion-Induced Changes and Glial Implants on the Regeneration of the Postcommissural Fornix by Christine C. Stichel-Gunkel |
| title_full_unstemmed | The Role of Microenvironment in Axonal Regeneration Influences of Lesion-Induced Changes and Glial Implants on the Regeneration of the Postcommissural Fornix by Christine C. Stichel-Gunkel |
| title_short | The Role of Microenvironment in Axonal Regeneration |
| title_sort | the role of microenvironment in axonal regeneration influences of lesion induced changes and glial implants on the regeneration of the postcommissural fornix |
| title_sub | Influences of Lesion-Induced Changes and Glial Implants on the Regeneration of the Postcommissural Fornix |
| topic | Neurosciences Animal Physiology Animal physiology Gliazelle (DE-588)4136721-2 gnd Implantation (DE-588)4026660-6 gnd Nervenregeneration (DE-588)4041641-0 gnd Nervenverletzung (DE-588)4041648-3 gnd Extrazellulärraum (DE-588)4205506-4 gnd Tiermodell (DE-588)4140660-6 gnd Axon (DE-588)4200576-0 gnd |
| topic_facet | Neurosciences Animal Physiology Animal physiology Gliazelle Implantation Nervenregeneration Nervenverletzung Extrazellulärraum Tiermodell Axon |
| url | https://doi.org/10.1007/978-3-642-60781-3 |
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