Signaling Networks and Cell Cycle Control: The Molecular Basis of Cancer and Other Diseases
The recent dramatic expansion of our knowledge about how cell surface receptors transmit signals to the nucleus, together with the identification of key signaling and cell-cycle-regulating molecules, has provided a major opportunity to search for novel targets for therapeutic intervention in many di...
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Weitere Verfasser: | |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Totowa, NJ
Humana Press
2000
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Schriftenreihe: | Cancer Drug Discovery and Development
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Schlagworte: | |
Online-Zugang: | UBR01 URL des Erstveröffentlichers |
Zusammenfassung: | The recent dramatic expansion of our knowledge about how cell surface receptors transmit signals to the nucleus, together with the identification of key signaling and cell-cycle-regulating molecules, has provided a major opportunity to search for novel targets for therapeutic intervention in many diseases. In Signaling Networks and Cell Cycle Control: The Molecular Basis of Cancer and Other Diseases, leading scientists summarize this knowledge and describe the effort to design and synthesize inhibiting molecules, as well as to evaluate their biochemical and biological activities. They review the relevant cell surface receptors, their ligands, and their downstream pathways. Also examined are the latest findings on the components of novel signaling networks controlling the activity of nuclear transcription factors and cell cycle regulatory molecules. Rich in cutting-edge insights and authoritative critical analysis, Signaling Networks and Cell Cycle Control: The Molecular Basis of Cancer and Other Diseases presents a wealth of information on the emerging principles of the field, as well as an invaluable guide for all experimental and clinical investigators of cell regulation and its rapidly emerging pharmacological opportunities today |
Beschreibung: | 1 Online-Ressource (XIV, 578 p. 97 illus) |
ISBN: | 9781592592180 |
DOI: | 10.1007/978-1-59259-218-0 |
Internformat
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discipline | Biologie Medizin |
doi_str_mv | 10.1007/978-1-59259-218-0 |
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spelling | Signaling Networks and Cell Cycle Control The Molecular Basis of Cancer and Other Diseases edited by J. Silvio Gutkind Totowa, NJ Humana Press 2000 1 Online-Ressource (XIV, 578 p. 97 illus) txt rdacontent c rdamedia cr rdacarrier Cancer Drug Discovery and Development The recent dramatic expansion of our knowledge about how cell surface receptors transmit signals to the nucleus, together with the identification of key signaling and cell-cycle-regulating molecules, has provided a major opportunity to search for novel targets for therapeutic intervention in many diseases. In Signaling Networks and Cell Cycle Control: The Molecular Basis of Cancer and Other Diseases, leading scientists summarize this knowledge and describe the effort to design and synthesize inhibiting molecules, as well as to evaluate their biochemical and biological activities. They review the relevant cell surface receptors, their ligands, and their downstream pathways. Also examined are the latest findings on the components of novel signaling networks controlling the activity of nuclear transcription factors and cell cycle regulatory molecules. Rich in cutting-edge insights and authoritative critical analysis, Signaling Networks and Cell Cycle Control: The Molecular Basis of Cancer and Other Diseases presents a wealth of information on the emerging principles of the field, as well as an invaluable guide for all experimental and clinical investigators of cell regulation and its rapidly emerging pharmacological opportunities today Pharmacy Zellzyklus (DE-588)4129960-7 gnd rswk-swf Signaltransduktion (DE-588)4318717-1 gnd rswk-swf Molekularpathologie (DE-588)4170396-0 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Signaltransduktion (DE-588)4318717-1 s Zellzyklus (DE-588)4129960-7 s Molekularpathologie (DE-588)4170396-0 s DE-604 Gutkind, J. Silvio edt Erscheint auch als Druck-Ausgabe 9781468496956 Erscheint auch als Druck-Ausgabe 9780896037106 Erscheint auch als Druck-Ausgabe 9781468496949 https://doi.org/10.1007/978-1-59259-218-0 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Signaling Networks and Cell Cycle Control The Molecular Basis of Cancer and Other Diseases Pharmacy Zellzyklus (DE-588)4129960-7 gnd Signaltransduktion (DE-588)4318717-1 gnd Molekularpathologie (DE-588)4170396-0 gnd |
subject_GND | (DE-588)4129960-7 (DE-588)4318717-1 (DE-588)4170396-0 (DE-588)4143413-4 |
title | Signaling Networks and Cell Cycle Control The Molecular Basis of Cancer and Other Diseases |
title_auth | Signaling Networks and Cell Cycle Control The Molecular Basis of Cancer and Other Diseases |
title_exact_search | Signaling Networks and Cell Cycle Control The Molecular Basis of Cancer and Other Diseases |
title_full | Signaling Networks and Cell Cycle Control The Molecular Basis of Cancer and Other Diseases edited by J. Silvio Gutkind |
title_fullStr | Signaling Networks and Cell Cycle Control The Molecular Basis of Cancer and Other Diseases edited by J. Silvio Gutkind |
title_full_unstemmed | Signaling Networks and Cell Cycle Control The Molecular Basis of Cancer and Other Diseases edited by J. Silvio Gutkind |
title_short | Signaling Networks and Cell Cycle Control |
title_sort | signaling networks and cell cycle control the molecular basis of cancer and other diseases |
title_sub | The Molecular Basis of Cancer and Other Diseases |
topic | Pharmacy Zellzyklus (DE-588)4129960-7 gnd Signaltransduktion (DE-588)4318717-1 gnd Molekularpathologie (DE-588)4170396-0 gnd |
topic_facet | Pharmacy Zellzyklus Signaltransduktion Molekularpathologie Aufsatzsammlung |
url | https://doi.org/10.1007/978-1-59259-218-0 |
work_keys_str_mv | AT gutkindjsilvio signalingnetworksandcellcyclecontrolthemolecularbasisofcancerandotherdiseases |