Sinus node inhibitors: A new concept in angina pectoris
Although surgical and catheter-based revascularization techniques have substan tially improved today's therapeutic potential in ischemic heart disease, in the majority of patients treatment will be conservative for a number of reasons, the cost-effectiveness of non-pharmacological approaches b...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Heidelberg
Steinkopff
1991
|
| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | Although surgical and catheter-based revascularization techniques have substan tially improved today's therapeutic potential in ischemic heart disease, in the majority of patients treatment will be conservative for a number of reasons, the cost-effectiveness of non-pharmacological approaches being of major importance. During the last two decades, drug development for ischemic heart disease has been impressive and many new compounds have been added to our therapeutic armamentarium. Nevertheless, where mode of action is concerned, it is interesting to note that, despite all these efforts, we are still confined to three categories of drugs. Antithrombotics and platelet-active agents aside, these concern nitrates, betablocking drugs and calcium antagonists, agents which reduce ischemia by diminishing cardiac work or wall stress,. thereby affecting myocardial oxygen demand and/or by improving coronary blood flow. Alone or in combination, these agents have proved to be efficacious in the treatment of angina pectoris or other symptoms of ischemic heart disease in a number of patients, but certainly not in all. Moreover, as side-effects are often a problem with current antianginal compounds, the physician may find himself restricted in his therapeutic capabilities and in need of new and, preferably, alternative forms of pharmacological treatment |
| Beschreibung: | 1 Online-Ressource (VIII, 64 p. 3 illus) |
| ISBN: | 9783642724589 |
| DOI: | 10.1007/978-3-642-72458-9 |
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| 520 | |a Although surgical and catheter-based revascularization techniques have substan tially improved today's therapeutic potential in ischemic heart disease, in the majority of patients treatment will be conservative for a number of reasons, the cost-effectiveness of non-pharmacological approaches being of major importance. During the last two decades, drug development for ischemic heart disease has been impressive and many new compounds have been added to our therapeutic armamentarium. Nevertheless, where mode of action is concerned, it is interesting to note that, despite all these efforts, we are still confined to three categories of drugs. Antithrombotics and platelet-active agents aside, these concern nitrates, betablocking drugs and calcium antagonists, agents which reduce ischemia by diminishing cardiac work or wall stress,. thereby affecting myocardial oxygen demand and/or by improving coronary blood flow. Alone or in combination, these agents have proved to be efficacious in the treatment of angina pectoris or other symptoms of ischemic heart disease in a number of patients, but certainly not in all. Moreover, as side-effects are often a problem with current antianginal compounds, the physician may find himself restricted in his therapeutic capabilities and in need of new and, preferably, alternative forms of pharmacological treatment | ||
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Datensatz im Suchindex
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| discipline | Medizin |
| doi_str_mv | 10.1007/978-3-642-72458-9 |
| format | Electronic eBook |
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| id | DE-604.BV046144105 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:24Z |
| institution | BVB |
| isbn | 9783642724589 |
| language | English |
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| physical | 1 Online-Ressource (VIII, 64 p. 3 illus) |
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| spelling | Sinus node inhibitors A new concept in angina pectoris edited by Å. Hjalmarson, W. J. Remme Heidelberg Steinkopff 1991 1 Online-Ressource (VIII, 64 p. 3 illus) txt rdacontent c rdamedia cr rdacarrier Although surgical and catheter-based revascularization techniques have substan tially improved today's therapeutic potential in ischemic heart disease, in the majority of patients treatment will be conservative for a number of reasons, the cost-effectiveness of non-pharmacological approaches being of major importance. During the last two decades, drug development for ischemic heart disease has been impressive and many new compounds have been added to our therapeutic armamentarium. Nevertheless, where mode of action is concerned, it is interesting to note that, despite all these efforts, we are still confined to three categories of drugs. Antithrombotics and platelet-active agents aside, these concern nitrates, betablocking drugs and calcium antagonists, agents which reduce ischemia by diminishing cardiac work or wall stress,. thereby affecting myocardial oxygen demand and/or by improving coronary blood flow. Alone or in combination, these agents have proved to be efficacious in the treatment of angina pectoris or other symptoms of ischemic heart disease in a number of patients, but certainly not in all. Moreover, as side-effects are often a problem with current antianginal compounds, the physician may find himself restricted in his therapeutic capabilities and in need of new and, preferably, alternative forms of pharmacological treatment Cardiology Pharmacology/Toxicology Toxicology Angina pectoris (DE-588)4002029-0 gnd rswk-swf UL-FS 49 CL (DE-588)4267656-3 gnd rswk-swf Angina pectoris (DE-588)4002029-0 s UL-FS 49 CL (DE-588)4267656-3 s DE-604 Hjalmarson, Å edt Remme, W. J. edt Erscheint auch als Druck-Ausgabe 9783798508613 Erscheint auch als Druck-Ausgabe 9783642724596 https://doi.org/10.1007/978-3-642-72458-9 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Sinus node inhibitors A new concept in angina pectoris Cardiology Pharmacology/Toxicology Toxicology Angina pectoris (DE-588)4002029-0 gnd UL-FS 49 CL (DE-588)4267656-3 gnd |
| subject_GND | (DE-588)4002029-0 (DE-588)4267656-3 |
| title | Sinus node inhibitors A new concept in angina pectoris |
| title_auth | Sinus node inhibitors A new concept in angina pectoris |
| title_exact_search | Sinus node inhibitors A new concept in angina pectoris |
| title_full | Sinus node inhibitors A new concept in angina pectoris edited by Å. Hjalmarson, W. J. Remme |
| title_fullStr | Sinus node inhibitors A new concept in angina pectoris edited by Å. Hjalmarson, W. J. Remme |
| title_full_unstemmed | Sinus node inhibitors A new concept in angina pectoris edited by Å. Hjalmarson, W. J. Remme |
| title_short | Sinus node inhibitors |
| title_sort | sinus node inhibitors a new concept in angina pectoris |
| title_sub | A new concept in angina pectoris |
| topic | Cardiology Pharmacology/Toxicology Toxicology Angina pectoris (DE-588)4002029-0 gnd UL-FS 49 CL (DE-588)4267656-3 gnd |
| topic_facet | Cardiology Pharmacology/Toxicology Toxicology Angina pectoris UL-FS 49 CL |
| url | https://doi.org/10.1007/978-3-642-72458-9 |
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