Leukemia and Lymphoma: Detection of Minimal Residual Disease
With the detection of the leukemias and lymphomas at levels almost four orders of magnitude below that obtainable by light microcopy, the groundwork has been laid for the development of reliable clinical tools and a redefinition of remission and relapse. In Leukemia and Lymphoma: Detection of Minima...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2003
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| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | With the detection of the leukemias and lymphomas at levels almost four orders of magnitude below that obtainable by light microcopy, the groundwork has been laid for the development of reliable clinical tools and a redefinition of remission and relapse. In Leukemia and Lymphoma: Detection of Minimal Residual Disease, hands-on experts describe and discuss the minimal residual disease (MRD) methods they have successfully pioneered for these hematological cancers. The techniques range from the use of patient-specific immunophenotypes to identify residual leukemia in patients who are in remission, to a variety of PCR techniques for detecting residual disease and measuring its level. Reverse transcription PCR (RT-PCR) is applied to acute myeloid leukemia (AML), chronic myelogenous leukemia (CML), and acute promyelocytic leukemia (APL). Other PCR methods are used for non-Hodgkin's lymphoma and for the monitoring of follicular lymphoma. Additional chapters address the use of real-time quantitative PCR (RQ-PCR), the emergent method of choice, in patients with acute lymphoblastic leukemia (ALL), the evaluation of MRD techniques in clinical trials, and the application of flow cytometry techniques. Comprehensive and innovative, Leukemia and Lymphoma: Detection of Minimal Residual Disease sets the stage for implementing the new standard detection and quantitation techniques as reliable tools for clinical decision-making, as well as for improved predictions and treatment outcomes |
| Beschreibung: | 1 Online-Ressource (XII, 257 p. 27 illus., 6 illus. in color) |
| ISBN: | 9781592593187 |
| DOI: | 10.1007/978-1-59259-318-7 |
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| 520 | |a With the detection of the leukemias and lymphomas at levels almost four orders of magnitude below that obtainable by light microcopy, the groundwork has been laid for the development of reliable clinical tools and a redefinition of remission and relapse. In Leukemia and Lymphoma: Detection of Minimal Residual Disease, hands-on experts describe and discuss the minimal residual disease (MRD) methods they have successfully pioneered for these hematological cancers. The techniques range from the use of patient-specific immunophenotypes to identify residual leukemia in patients who are in remission, to a variety of PCR techniques for detecting residual disease and measuring its level. Reverse transcription PCR (RT-PCR) is applied to acute myeloid leukemia (AML), chronic myelogenous leukemia (CML), and acute promyelocytic leukemia (APL). Other PCR methods are used for non-Hodgkin's lymphoma and for the monitoring of follicular lymphoma. Additional chapters address the use of real-time quantitative PCR (RQ-PCR), the emergent method of choice, in patients with acute lymphoblastic leukemia (ALL), the evaluation of MRD techniques in clinical trials, and the application of flow cytometry techniques. Comprehensive and innovative, Leukemia and Lymphoma: Detection of Minimal Residual Disease sets the stage for implementing the new standard detection and quantitation techniques as reliable tools for clinical decision-making, as well as for improved predictions and treatment outcomes | ||
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Datensatz im Suchindex
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| dewey-full | 616.15 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
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| dewey-sort | 3616.15 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.1007/978-1-59259-318-7 |
| format | Electronic eBook |
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| id | DE-604.BV046144013 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:24Z |
| institution | BVB |
| isbn | 9781592593187 |
| language | English |
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| physical | 1 Online-Ressource (XII, 257 p. 27 illus., 6 illus. in color) |
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| spelling | Leukemia and Lymphoma Detection of Minimal Residual Disease edited by Theodore F. Zipf, Dennis A. Johnston Totowa, NJ Humana Press 2003 1 Online-Ressource (XII, 257 p. 27 illus., 6 illus. in color) txt rdacontent c rdamedia cr rdacarrier With the detection of the leukemias and lymphomas at levels almost four orders of magnitude below that obtainable by light microcopy, the groundwork has been laid for the development of reliable clinical tools and a redefinition of remission and relapse. In Leukemia and Lymphoma: Detection of Minimal Residual Disease, hands-on experts describe and discuss the minimal residual disease (MRD) methods they have successfully pioneered for these hematological cancers. The techniques range from the use of patient-specific immunophenotypes to identify residual leukemia in patients who are in remission, to a variety of PCR techniques for detecting residual disease and measuring its level. Reverse transcription PCR (RT-PCR) is applied to acute myeloid leukemia (AML), chronic myelogenous leukemia (CML), and acute promyelocytic leukemia (APL). Other PCR methods are used for non-Hodgkin's lymphoma and for the monitoring of follicular lymphoma. Additional chapters address the use of real-time quantitative PCR (RQ-PCR), the emergent method of choice, in patients with acute lymphoblastic leukemia (ALL), the evaluation of MRD techniques in clinical trials, and the application of flow cytometry techniques. Comprehensive and innovative, Leukemia and Lymphoma: Detection of Minimal Residual Disease sets the stage for implementing the new standard detection and quantitation techniques as reliable tools for clinical decision-making, as well as for improved predictions and treatment outcomes Hematology Zipf, Theodore F. edt Johnston, Dennis A. edt Erscheint auch als Druck-Ausgabe 9781617372797 Erscheint auch als Druck-Ausgabe 9781468497434 Erscheint auch als Druck-Ausgabe 9780896039667 https://doi.org/10.1007/978-1-59259-318-7 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Leukemia and Lymphoma Detection of Minimal Residual Disease Hematology |
| title | Leukemia and Lymphoma Detection of Minimal Residual Disease |
| title_auth | Leukemia and Lymphoma Detection of Minimal Residual Disease |
| title_exact_search | Leukemia and Lymphoma Detection of Minimal Residual Disease |
| title_full | Leukemia and Lymphoma Detection of Minimal Residual Disease edited by Theodore F. Zipf, Dennis A. Johnston |
| title_fullStr | Leukemia and Lymphoma Detection of Minimal Residual Disease edited by Theodore F. Zipf, Dennis A. Johnston |
| title_full_unstemmed | Leukemia and Lymphoma Detection of Minimal Residual Disease edited by Theodore F. Zipf, Dennis A. Johnston |
| title_short | Leukemia and Lymphoma |
| title_sort | leukemia and lymphoma detection of minimal residual disease |
| title_sub | Detection of Minimal Residual Disease |
| topic | Hematology |
| topic_facet | Hematology |
| url | https://doi.org/10.1007/978-1-59259-318-7 |
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