Advances in Swine in Biomedical Research: Volume 2
Similarities in structure and function between pigs and human beings include size, feeding patterns, digestive physiology, dietary habits, kidney structure and function, pulmo nary vascular bed structure, coronary artery distribution, propensity to obesity, respiratory rates, tidal volumes and soci...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Boston, MA
Springer US
1996
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| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | Similarities in structure and function between pigs and human beings include size, feeding patterns, digestive physiology, dietary habits, kidney structure and function, pulmo nary vascular bed structure, coronary artery distribution, propensity to obesity, respiratory rates, tidal volumes and social behaviors. Since the pig is an omnivore, it provides an adaptable model to evaluate chronic and acute exposures to xenobiotics such as alcohoL caffeine, tobacco, food additives and environmental pollutants. Swine have been used successfully as models to evaluate alcoholism, diabetes, absorption, digestion, total paren teral nutrition, organ transplantation, atherosclerosis, exercise, hypertension. hemorrhagic hypotension, melanoma, gingivitis, obstructive and reflux nephropathy. osteochondrosis. dermal healing and septic shock. A severe and worsening shortage of organs and tissues for transplantation in patients with severe organ failure has encouraged the consideration of inter species or xenotransplan tation. In developing programs toward this end, the pig generally is viewed as the preferred donor because of its size, physiology and availability. The pig harbors relatively few diseases which could be transmitted inadvertently to human patients. The ability to genetically modify swine to ameliorate the consequences of the human immune response offers a further significant advantage. Another important consideration for an animal model is that basic biologic back ground information be available for investigators to design future prospective studies |
| Beschreibung: | 1 Online-Ressource (XVIII, 483 p) |
| ISBN: | 9781461558859 |
| DOI: | 10.1007/978-1-4615-5885-9 |
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| 520 | |a Similarities in structure and function between pigs and human beings include size, feeding patterns, digestive physiology, dietary habits, kidney structure and function, pulmo nary vascular bed structure, coronary artery distribution, propensity to obesity, respiratory rates, tidal volumes and social behaviors. Since the pig is an omnivore, it provides an adaptable model to evaluate chronic and acute exposures to xenobiotics such as alcohoL caffeine, tobacco, food additives and environmental pollutants. Swine have been used successfully as models to evaluate alcoholism, diabetes, absorption, digestion, total paren teral nutrition, organ transplantation, atherosclerosis, exercise, hypertension. hemorrhagic hypotension, melanoma, gingivitis, obstructive and reflux nephropathy. osteochondrosis. dermal healing and septic shock. A severe and worsening shortage of organs and tissues for transplantation in patients with severe organ failure has encouraged the consideration of inter species or xenotransplan tation. In developing programs toward this end, the pig generally is viewed as the preferred donor because of its size, physiology and availability. The pig harbors relatively few diseases which could be transmitted inadvertently to human patients. The ability to genetically modify swine to ameliorate the consequences of the human immune response offers a further significant advantage. Another important consideration for an animal model is that basic biologic back ground information be available for investigators to design future prospective studies | ||
| 650 | 4 | |a Infectious Diseases | |
| 650 | 4 | |a Nutrition | |
| 650 | 4 | |a Pharmacology/Toxicology | |
| 650 | 4 | |a Human Genetics | |
| 650 | 4 | |a Animal Physiology | |
| 650 | 4 | |a Biological and Medical Physics, Biophysics | |
| 650 | 4 | |a Emerging infectious diseases | |
| 650 | 4 | |a Nutrition | |
| 650 | 4 | |a Toxicology | |
| 650 | 4 | |a Human genetics | |
| 650 | 4 | |a Animal physiology | |
| 700 | 1 | |a Tumbleson, Mike E. |4 edt | |
| 700 | 1 | |a Schook, Lawrence B. |4 edt | |
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Datensatz im Suchindex
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| author2 | Tumbleson, Mike E. Schook, Lawrence B. |
| author2_role | edt edt |
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| author_facet | Tumbleson, Mike E. Schook, Lawrence B. |
| building | Verbundindex |
| bvnumber | BV046143559 |
| collection | ZDB-2-SME |
| ctrlnum | (ZDB-2-SME)978-1-4615-5885-9 (OCoLC)1119076919 (DE-599)BVBBV046143559 |
| dewey-full | 616.9 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.9 |
| dewey-search | 616.9 |
| dewey-sort | 3616.9 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.1007/978-1-4615-5885-9 |
| format | Electronic eBook |
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| id | DE-604.BV046143559 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:23Z |
| institution | BVB |
| isbn | 9781461558859 |
| language | English |
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| oclc_num | 1119076919 |
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| physical | 1 Online-Ressource (XVIII, 483 p) |
| psigel | ZDB-2-SME ZDB-2-SME_1990/2004 ZDB-2-SME ZDB-2-SME_1990/2004 |
| publishDate | 1996 |
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| publisher | Springer US |
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| spelling | Advances in Swine in Biomedical Research Volume 2 edited by Mike E. Tumbleson, Lawrence B. Schook Boston, MA Springer US 1996 1 Online-Ressource (XVIII, 483 p) txt rdacontent c rdamedia cr rdacarrier Similarities in structure and function between pigs and human beings include size, feeding patterns, digestive physiology, dietary habits, kidney structure and function, pulmo nary vascular bed structure, coronary artery distribution, propensity to obesity, respiratory rates, tidal volumes and social behaviors. Since the pig is an omnivore, it provides an adaptable model to evaluate chronic and acute exposures to xenobiotics such as alcohoL caffeine, tobacco, food additives and environmental pollutants. Swine have been used successfully as models to evaluate alcoholism, diabetes, absorption, digestion, total paren teral nutrition, organ transplantation, atherosclerosis, exercise, hypertension. hemorrhagic hypotension, melanoma, gingivitis, obstructive and reflux nephropathy. osteochondrosis. dermal healing and septic shock. A severe and worsening shortage of organs and tissues for transplantation in patients with severe organ failure has encouraged the consideration of inter species or xenotransplan tation. In developing programs toward this end, the pig generally is viewed as the preferred donor because of its size, physiology and availability. The pig harbors relatively few diseases which could be transmitted inadvertently to human patients. The ability to genetically modify swine to ameliorate the consequences of the human immune response offers a further significant advantage. Another important consideration for an animal model is that basic biologic back ground information be available for investigators to design future prospective studies Infectious Diseases Nutrition Pharmacology/Toxicology Human Genetics Animal Physiology Biological and Medical Physics, Biophysics Emerging infectious diseases Toxicology Human genetics Animal physiology Tumbleson, Mike E. edt Schook, Lawrence B. edt Erscheint auch als Druck-Ausgabe 9780306454967 Erscheint auch als Druck-Ausgabe 9781461376996 Erscheint auch als Druck-Ausgabe 9781461558866 https://doi.org/10.1007/978-1-4615-5885-9 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Advances in Swine in Biomedical Research Volume 2 Infectious Diseases Nutrition Pharmacology/Toxicology Human Genetics Animal Physiology Biological and Medical Physics, Biophysics Emerging infectious diseases Toxicology Human genetics Animal physiology |
| title | Advances in Swine in Biomedical Research Volume 2 |
| title_auth | Advances in Swine in Biomedical Research Volume 2 |
| title_exact_search | Advances in Swine in Biomedical Research Volume 2 |
| title_full | Advances in Swine in Biomedical Research Volume 2 edited by Mike E. Tumbleson, Lawrence B. Schook |
| title_fullStr | Advances in Swine in Biomedical Research Volume 2 edited by Mike E. Tumbleson, Lawrence B. Schook |
| title_full_unstemmed | Advances in Swine in Biomedical Research Volume 2 edited by Mike E. Tumbleson, Lawrence B. Schook |
| title_short | Advances in Swine in Biomedical Research |
| title_sort | advances in swine in biomedical research volume 2 |
| title_sub | Volume 2 |
| topic | Infectious Diseases Nutrition Pharmacology/Toxicology Human Genetics Animal Physiology Biological and Medical Physics, Biophysics Emerging infectious diseases Toxicology Human genetics Animal physiology |
| topic_facet | Infectious Diseases Nutrition Pharmacology/Toxicology Human Genetics Animal Physiology Biological and Medical Physics, Biophysics Emerging infectious diseases Toxicology Human genetics Animal physiology |
| url | https://doi.org/10.1007/978-1-4615-5885-9 |
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