The lock and key of medicine: monoclonal antibodies and the transformation of healthcare
Hunting for the elusive "magic bullet" -- A hesitant start: Patents, politics, and process -- Breakthroughs at the bench -- The first medical applications -- Joy, disappointment, determination: Early clinical tests -- The wild West of antibody commercialization -- The challenge of monoclon...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
New Haven ; London
Yale University Press
[2015]
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| Schlagworte: | |
| Online-Zugang: | Autorenbiografie Verlagsangaben |
| Zusammenfassung: | Hunting for the elusive "magic bullet" -- A hesitant start: Patents, politics, and process -- Breakthroughs at the bench -- The first medical applications -- Joy, disappointment, determination: Early clinical tests -- The wild West of antibody commercialization -- The challenge of monoclonal antibody drugs -- Antibody engineering: A renaissance for mab therapeutics -- Blockbuster mab drugs -- A quiet revolution: The legacy of monoclonal antibodies This book is the first to tell the extraordinary yet unheralded history of monoclonal antibodies. Often referred to as Mabs, they are unfamiliar to most nonscientists, yet these microscopic protein molecules are everywhere, quietly shaping our lives and healthcare. Discovered in the mid-1970s in the laboratory where Watson and Crick had earlier unveiled the structure of DNA, Mabs have radically changed understandings of the pathways of disease. They have enabled faster, cheaper, and more accurate clinical diagnostic testing on a vast scale. And they have played a fundamental role in pharmaceutical innovation, leading to such developments as recombinant interferon and insulin, and personalized drug therapies such as Herceptin. Today Mabs constitute six of the world's top ten blockbuster drugs and make up a third of new introduced treatments. -- |
| Beschreibung: | Literaturverzeichnis: Seiten 301-305 |
| Beschreibung: | xxv, 316 Seiten Illustrationen, Diagramme cm |
| ISBN: | 0300167733 9780300167733 |
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| illustrated | Illustrated |
| indexdate | 2024-07-10T08:29:50Z |
| institution | BVB |
| isbn | 0300167733 9780300167733 |
| language | English |
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| physical | xxv, 316 Seiten Illustrationen, Diagramme cm |
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| publishDateSort | 2015 |
| publisher | Yale University Press |
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| spelling | Marks, Lara 1963- Verfasser (DE-588)131650432 aut The lock and key of medicine monoclonal antibodies and the transformation of healthcare Lara V. Marks New Haven ; London Yale University Press [2015] © 2015 xxv, 316 Seiten Illustrationen, Diagramme cm txt rdacontent n rdamedia nc rdacarrier Literaturverzeichnis: Seiten 301-305 Hunting for the elusive "magic bullet" -- A hesitant start: Patents, politics, and process -- Breakthroughs at the bench -- The first medical applications -- Joy, disappointment, determination: Early clinical tests -- The wild West of antibody commercialization -- The challenge of monoclonal antibody drugs -- Antibody engineering: A renaissance for mab therapeutics -- Blockbuster mab drugs -- A quiet revolution: The legacy of monoclonal antibodies This book is the first to tell the extraordinary yet unheralded history of monoclonal antibodies. Often referred to as Mabs, they are unfamiliar to most nonscientists, yet these microscopic protein molecules are everywhere, quietly shaping our lives and healthcare. Discovered in the mid-1970s in the laboratory where Watson and Crick had earlier unveiled the structure of DNA, Mabs have radically changed understandings of the pathways of disease. They have enabled faster, cheaper, and more accurate clinical diagnostic testing on a vast scale. And they have played a fundamental role in pharmaceutical innovation, leading to such developments as recombinant interferon and insulin, and personalized drug therapies such as Herceptin. Today Mabs constitute six of the world's top ten blockbuster drugs and make up a third of new introduced treatments. -- Antikörper (DE-588)4002290-0 gnd rswk-swf Antikörper (DE-588)4002290-0 s DE-604 http://www.loc.gov/catdir/enhancements/fy1605/2015930850-b.html Autorenbiografie http://www.loc.gov/catdir/enhancements/fy1605/2015930850-d.html Verlagsangaben |
| spellingShingle | Marks, Lara 1963- The lock and key of medicine monoclonal antibodies and the transformation of healthcare Antikörper (DE-588)4002290-0 gnd |
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| title | The lock and key of medicine monoclonal antibodies and the transformation of healthcare |
| title_auth | The lock and key of medicine monoclonal antibodies and the transformation of healthcare |
| title_exact_search | The lock and key of medicine monoclonal antibodies and the transformation of healthcare |
| title_full | The lock and key of medicine monoclonal antibodies and the transformation of healthcare Lara V. Marks |
| title_fullStr | The lock and key of medicine monoclonal antibodies and the transformation of healthcare Lara V. Marks |
| title_full_unstemmed | The lock and key of medicine monoclonal antibodies and the transformation of healthcare Lara V. Marks |
| title_short | The lock and key of medicine |
| title_sort | the lock and key of medicine monoclonal antibodies and the transformation of healthcare |
| title_sub | monoclonal antibodies and the transformation of healthcare |
| topic | Antikörper (DE-588)4002290-0 gnd |
| topic_facet | Antikörper |
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