Cellular Signal Transduction in Toxicology and Pharmacology: Data Collection, Analysis, and Interpretation
Covering a key topic due to growing research into the role of signaling mechanisms in toxicology, this book focuses on practical approaches for informatics, big data, and complex data sets.* Combines fundamentals / basics with experimental applications that can help those involved in preclinical dru...
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Hoboken, NJ
Wiley
2019
|
| Schlagworte: | |
| Zusammenfassung: | Covering a key topic due to growing research into the role of signaling mechanisms in toxicology, this book focuses on practical approaches for informatics, big data, and complex data sets.* Combines fundamentals / basics with experimental applications that can help those involved in preclinical drug studies and translational research* Includes detailed presentations of study methodology and data collection, analysis, and interpretation* Discusses tools like experimental design, sample handling, analytical measurement techniques |
| Beschreibung: | Provides practical approaches for informatics, big data, and complex data sets of cellular signal transduction in toxicology and pharmacologyThis book offers a thorough discussion of signal transduction mechanisms and approaches that can help toxicologists and pharmacologists guide future study design and data interpretation. It gives readers a solid background in signal transduction networks, while supplying the tools necessary for further research in this expanding area. These tools include a discussion of experimental design, sample handling, analytical measurement techniques, and data analysis and interpretation (including novel modeling approaches).Cellular Signal Transduction in Toxicology and Pharmacology: Data Collection, Analysis, and Interpretation is organized hierarchically. The first four chapters describe the architecture of signaling networks-from a physical basis of understanding signaling through mechanisms, physiological response, and human disease. . - The last half of the book is a how-to for incorporating signal transduction research into your portfolio-from designing signal transduction studies, to measuring and monitoring signaling responses, interpreting and transforming data into useable information, and finally outlining critical future needs in signal transduction research.* Covers a topic of key interest to toxicologists as there is a growing body of research into the role of signaling mechanisms in toxicology* Features a practical focus on modern approaches like the use of informatics, big data, and complex data sets* Combines fundamentals/basics with experimental applications that can help those involved in preclinical drug studies and translational research* Includes detailed presentations of study methodology and data collection, analysis, and interpretation* Discusses tools like experimental design, sample handling, . - analytical measurement techniquesWritten for an audience with a background in biochemistry or cell biology, List of Contributors; About the Editors; Preface; Chapter 1: Introduction to cellular signal transduction: The connection between a biological system and its surroundings; Jonathan Boyd, Richard Neubig, Alice Han, Maren Prediger; Chapter 2: Mechanisms of cellular signal transduction; Richard Neubig, Jonathan Boyd, Julia Mouch, Nicole Prince; Chapter 3: From cellular mechanisms to physiological responses: Functional signal integration across multiple biological levels; Robert Newman; Chapter 4: Signal transduction in disease: Relating cell signaling to morbidity and mortality; Patricia E. Ganey, Sean E. Misek; Chapter 5: Experimental design in signal transduction; Weimin Gao, Meghan Cromie, Qian Wang, Zhongwei Liu, Song Tang, Julie Miller; Chapter 6: Techniques for measuring cellular signal transduction; Julie Miller, Weimin Gao, Meghan Cromie; Chapter 7: Computational methods for signal transduction: A network approach; Giovanni Scardoni, Gabriele Tosadori, John Morris, A. Pegoraro, Sakshi Pratap, Carlo Laudanna, Alice Han; Chapter 8: A toxicological application of signal transduction: Early cellular changes can be indicative of toxicity; Julie Miller, Nicole Prince, Julia Mouch, Jonathan Boyd; Chapter 9: Future research in signaling; Jonathan Boyd, Nicole Prince; Index |
| Beschreibung: | xx, 310 pages illustrations |
| ISBN: | 9781119060260 |
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| 500 | |a Provides practical approaches for informatics, big data, and complex data sets of cellular signal transduction in toxicology and pharmacologyThis book offers a thorough discussion of signal transduction mechanisms and approaches that can help toxicologists and pharmacologists guide future study design and data interpretation. It gives readers a solid background in signal transduction networks, while supplying the tools necessary for further research in this expanding area. These tools include a discussion of experimental design, sample handling, analytical measurement techniques, and data analysis and interpretation (including novel modeling approaches).Cellular Signal Transduction in Toxicology and Pharmacology: Data Collection, Analysis, and Interpretation is organized hierarchically. The first four chapters describe the architecture of signaling networks-from a physical basis of understanding signaling through mechanisms, physiological response, and human disease. . - The last half of the book is a how-to for incorporating signal transduction research into your portfolio-from designing signal transduction studies, to measuring and monitoring signaling responses, interpreting and transforming data into useable information, and finally outlining critical future needs in signal transduction research.* Covers a topic of key interest to toxicologists as there is a growing body of research into the role of signaling mechanisms in toxicology* Features a practical focus on modern approaches like the use of informatics, big data, and complex data sets* Combines fundamentals/basics with experimental applications that can help those involved in preclinical drug studies and translational research* Includes detailed presentations of study methodology and data collection, analysis, and interpretation* Discusses tools like experimental design, sample handling, . - analytical measurement techniquesWritten for an audience with a background in biochemistry or cell biology, | ||
| 500 | |a List of Contributors; About the Editors; Preface; Chapter 1: Introduction to cellular signal transduction: The connection between a biological system and its surroundings; Jonathan Boyd, Richard Neubig, Alice Han, Maren Prediger; Chapter 2: Mechanisms of cellular signal transduction; Richard Neubig, Jonathan Boyd, Julia Mouch, Nicole Prince; Chapter 3: From cellular mechanisms to physiological responses: Functional signal integration across multiple biological levels; Robert Newman; Chapter 4: Signal transduction in disease: Relating cell signaling to morbidity and mortality; Patricia E. Ganey, Sean E. Misek; Chapter 5: Experimental design in signal transduction; Weimin Gao, Meghan Cromie, Qian Wang, Zhongwei Liu, Song Tang, Julie Miller; Chapter 6: Techniques for measuring cellular signal transduction; Julie Miller, Weimin Gao, Meghan Cromie; Chapter 7: Computational methods for signal transduction: A network approach; Giovanni Scardoni, Gabriele Tosadori, John Morris, A. Pegoraro, Sakshi Pratap, Carlo Laudanna, Alice Han; Chapter 8: A toxicological application of signal transduction: Early cellular changes can be indicative of toxicity; Julie Miller, Nicole Prince, Julia Mouch, Jonathan Boyd; Chapter 9: Future research in signaling; Jonathan Boyd, Nicole Prince; Index | ||
| 520 | |a Covering a key topic due to growing research into the role of signaling mechanisms in toxicology, this book focuses on practical approaches for informatics, big data, and complex data sets.* Combines fundamentals / basics with experimental applications that can help those involved in preclinical drug studies and translational research* Includes detailed presentations of study methodology and data collection, analysis, and interpretation* Discusses tools like experimental design, sample handling, analytical measurement techniques | ||
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| isbn | 9781119060260 |
| language | English |
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| spelling | Cellular Signal Transduction in Toxicology and Pharmacology Data Collection, Analysis, and Interpretation edited by Jonathan W. Boyd, Richard R. Neubig Hoboken, NJ Wiley 2019 xx, 310 pages illustrations txt rdacontent n rdamedia nc rdacarrier Provides practical approaches for informatics, big data, and complex data sets of cellular signal transduction in toxicology and pharmacologyThis book offers a thorough discussion of signal transduction mechanisms and approaches that can help toxicologists and pharmacologists guide future study design and data interpretation. It gives readers a solid background in signal transduction networks, while supplying the tools necessary for further research in this expanding area. These tools include a discussion of experimental design, sample handling, analytical measurement techniques, and data analysis and interpretation (including novel modeling approaches).Cellular Signal Transduction in Toxicology and Pharmacology: Data Collection, Analysis, and Interpretation is organized hierarchically. The first four chapters describe the architecture of signaling networks-from a physical basis of understanding signaling through mechanisms, physiological response, and human disease. . - The last half of the book is a how-to for incorporating signal transduction research into your portfolio-from designing signal transduction studies, to measuring and monitoring signaling responses, interpreting and transforming data into useable information, and finally outlining critical future needs in signal transduction research.* Covers a topic of key interest to toxicologists as there is a growing body of research into the role of signaling mechanisms in toxicology* Features a practical focus on modern approaches like the use of informatics, big data, and complex data sets* Combines fundamentals/basics with experimental applications that can help those involved in preclinical drug studies and translational research* Includes detailed presentations of study methodology and data collection, analysis, and interpretation* Discusses tools like experimental design, sample handling, . - analytical measurement techniquesWritten for an audience with a background in biochemistry or cell biology, List of Contributors; About the Editors; Preface; Chapter 1: Introduction to cellular signal transduction: The connection between a biological system and its surroundings; Jonathan Boyd, Richard Neubig, Alice Han, Maren Prediger; Chapter 2: Mechanisms of cellular signal transduction; Richard Neubig, Jonathan Boyd, Julia Mouch, Nicole Prince; Chapter 3: From cellular mechanisms to physiological responses: Functional signal integration across multiple biological levels; Robert Newman; Chapter 4: Signal transduction in disease: Relating cell signaling to morbidity and mortality; Patricia E. Ganey, Sean E. Misek; Chapter 5: Experimental design in signal transduction; Weimin Gao, Meghan Cromie, Qian Wang, Zhongwei Liu, Song Tang, Julie Miller; Chapter 6: Techniques for measuring cellular signal transduction; Julie Miller, Weimin Gao, Meghan Cromie; Chapter 7: Computational methods for signal transduction: A network approach; Giovanni Scardoni, Gabriele Tosadori, John Morris, A. Pegoraro, Sakshi Pratap, Carlo Laudanna, Alice Han; Chapter 8: A toxicological application of signal transduction: Early cellular changes can be indicative of toxicity; Julie Miller, Nicole Prince, Julia Mouch, Jonathan Boyd; Chapter 9: Future research in signaling; Jonathan Boyd, Nicole Prince; Index Covering a key topic due to growing research into the role of signaling mechanisms in toxicology, this book focuses on practical approaches for informatics, big data, and complex data sets.* Combines fundamentals / basics with experimental applications that can help those involved in preclinical drug studies and translational research* Includes detailed presentations of study methodology and data collection, analysis, and interpretation* Discusses tools like experimental design, sample handling, analytical measurement techniques Signaltransduktion (DE-588)4318717-1 gnd rswk-swf Molekularpharmakologie (DE-588)4170397-2 gnd rswk-swf Toxikologie (DE-588)4060538-3 gnd rswk-swf Chemie Molekularpharmakologie (DE-588)4170397-2 s Signaltransduktion (DE-588)4318717-1 s Toxikologie (DE-588)4060538-3 s DE-604 Boyd, Jonathan W. 1975- Sonstige (DE-588)1186865326 oth Neubig, Richard R. Sonstige oth Erscheint auch als Online-Ausgabe, PDF 978-1-119-06025-3 Erscheint auch als Online-Ausgabe, EPUB 978-1-119-06016-1 |
| spellingShingle | Cellular Signal Transduction in Toxicology and Pharmacology Data Collection, Analysis, and Interpretation Signaltransduktion (DE-588)4318717-1 gnd Molekularpharmakologie (DE-588)4170397-2 gnd Toxikologie (DE-588)4060538-3 gnd |
| subject_GND | (DE-588)4318717-1 (DE-588)4170397-2 (DE-588)4060538-3 |
| title | Cellular Signal Transduction in Toxicology and Pharmacology Data Collection, Analysis, and Interpretation |
| title_auth | Cellular Signal Transduction in Toxicology and Pharmacology Data Collection, Analysis, and Interpretation |
| title_exact_search | Cellular Signal Transduction in Toxicology and Pharmacology Data Collection, Analysis, and Interpretation |
| title_full | Cellular Signal Transduction in Toxicology and Pharmacology Data Collection, Analysis, and Interpretation edited by Jonathan W. Boyd, Richard R. Neubig |
| title_fullStr | Cellular Signal Transduction in Toxicology and Pharmacology Data Collection, Analysis, and Interpretation edited by Jonathan W. Boyd, Richard R. Neubig |
| title_full_unstemmed | Cellular Signal Transduction in Toxicology and Pharmacology Data Collection, Analysis, and Interpretation edited by Jonathan W. Boyd, Richard R. Neubig |
| title_short | Cellular Signal Transduction in Toxicology and Pharmacology |
| title_sort | cellular signal transduction in toxicology and pharmacology data collection analysis and interpretation |
| title_sub | Data Collection, Analysis, and Interpretation |
| topic | Signaltransduktion (DE-588)4318717-1 gnd Molekularpharmakologie (DE-588)4170397-2 gnd Toxikologie (DE-588)4060538-3 gnd |
| topic_facet | Signaltransduktion Molekularpharmakologie Toxikologie |
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