The genetics of African populations in health and disease:
"The birthplace of modern humans, Africa, has the highest genetic diversity in the world, yet it remains vastly understudied. With biomedical research increasingly focused on human variation, studying the large population size and number of mutations in African genomes could unravel the complex...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Cambridge, United Kingdon ; New York, NY
Cambridge University Press
2020
|
| Schriftenreihe: | Cambridge studies in biological and evolutionary anthropology
[84] |
| Schlagworte: | |
| Zusammenfassung: | "The birthplace of modern humans, Africa, has the highest genetic diversity in the world, yet it remains vastly understudied. With biomedical research increasingly focused on human variation, studying the large population size and number of mutations in African genomes could unravel the complexity of phenotypic traits underlying the biology of our species and hold huge potential for scientific and medical advances. An initial chapter 'conceptualizes Africa', providing relevant terminology. The first section covers genetic history and population structure. The next section looks at the genetic basis of common infectious diseases, such as leishmaniasis, malaria and tuberculosis, with a final part considering common non-communicable diseases, such as diabetes, hypertension, obesity, heart disease and cancer. Gene environment interaction under globalization and the burden of diseases of lifestyle are included. For researchers and graduate students in biological anthropology, genetic anthropology, human and population genetics, and public health"--Provided by publisher |
| Beschreibung: | xi, 338 Seiten Illustrationen, Diagramme |
| ISBN: | 9781107072022 1107072026 |
Internformat
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| 245 | 1 | 0 | |a The genetics of African populations in health and disease |c edited by Muntaser E. Ibrahim, Charles N. Rotimi |
| 264 | 1 | |a Cambridge, United Kingdon ; New York, NY |b Cambridge University Press |c 2020 | |
| 300 | |a xi, 338 Seiten |b Illustrationen, Diagramme | ||
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| 490 | 1 | |a Cambridge studies in biological and evolutionary anthropology |v [84] | |
| 505 | 8 | |a Machine generated contents note: 1. Reflections on conceptualizing Africa for biological studies with a historical component: a small essay S.O. Y. Keita; 2. History and genetics in Africa: multidisciplinary efforts Shomarka Omar Y. Keita and Muntaser E. Ibrahim; 3. Disease, selection, and evolution in the African landscape Muntaser Ibrahim and Endashaw Bekele; 4. Genetic susceptibility to visceral leishmaniasis Hiba S. Mohamed, Muntaser E. Ibrahim and Jenefer M. Blackwell; 5. Genetics of infection in Sub-Saharan Africa: what can the study of Mendelian immunodeficiency disorders contribute? Melanie Newport; 6. Pharmacogenomics and infectious diseases in Africa: an evolutionary perspective Jennifer L. Baker, Daniel Shriner, Amy R. Bentley and Charles N. Rotimi; 7. A glimpse into pharmacogenomics in Africa Collet Dandara and Alice Matimba; 8. Genomics of cardiometabolic disorders in Sub-Saharan Africa Sally N. Adebamowo, Fasil Tekola-Ayele, Adebowale A. Adeyemo and Charles N. Rotimi; 9. Breast cancer in African populations Konduru S. Sastry and Lotfi Chouchane; 10. Socio-biological transition and cancer: prospects for Africa Sulma Mahmoud, Khalid O. Alfarouk, Ahmed M. Elhassan, Kamal Hamad and Muntaser E. Ibrahim; 11. The genetic epidemiology of orphan diseases in North Africa Lilia Romdhane, Olfa Messaoud, Rym Kefi, Afaf Tiar, Ahlem Amouri, Mourad Mokni, Neji Tebib, Mohamed Zghal, Abdelhamid Barakat, Ahmed Houmeida, Mariem Bozguiya, Mohamed Othman, Ghada El Qameh and Sonia Abdelhak; 12. Birth defects and genetic disease in Sub-Saharan Africa Ambroise Wonkam; 13. Neurogenetic disorders in Africa: hereditary spastic paraplegia: a case study Liena E. O. Elsayed, Ammar E. M. Ahmed and Giovanni Stevanin | |
| 520 | 3 | |a "The birthplace of modern humans, Africa, has the highest genetic diversity in the world, yet it remains vastly understudied. With biomedical research increasingly focused on human variation, studying the large population size and number of mutations in African genomes could unravel the complexity of phenotypic traits underlying the biology of our species and hold huge potential for scientific and medical advances. An initial chapter 'conceptualizes Africa', providing relevant terminology. The first section covers genetic history and population structure. The next section looks at the genetic basis of common infectious diseases, such as leishmaniasis, malaria and tuberculosis, with a final part considering common non-communicable diseases, such as diabetes, hypertension, obesity, heart disease and cancer. Gene environment interaction under globalization and the burden of diseases of lifestyle are included. For researchers and graduate students in biological anthropology, genetic anthropology, human and population genetics, and public health"--Provided by publisher | |
| 650 | 0 | 7 | |a Genetische Variabilität |0 (DE-588)4264352-1 |2 gnd |9 rswk-swf |
| 653 | 0 | |a African Continental Ancestry Group / genetics | |
| 653 | 0 | |a Genetic Predisposition to Disease | |
| 653 | 0 | |a Communicable Diseases / genetics | |
| 653 | 0 | |a Noncommunicable Diseases | |
| 653 | 0 | |a Genetic Profile | |
| 653 | 2 | |a Africa | |
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| 700 | 1 | |a Ibrahim, Muntaser |d 1957- |0 (DE-588)1203751575 |4 edt | |
| 700 | 1 | |a Rotimi, Charles N. |d 1957- |0 (DE-588)1203751915 |4 edt | |
| 830 | 0 | |a Cambridge studies in biological and evolutionary anthropology |v [84] |w (DE-604)BV025266531 |9 84 | |
| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-030945650 | |
Datensatz im Suchindex
| _version_ | 1817711161788858368 |
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| adam_text | |
| any_adam_object | |
| author2 | Ibrahim, Muntaser 1957- Rotimi, Charles N. 1957- |
| author2_role | edt edt |
| author2_variant | m i mi c n r cn cnr |
| author_GND | (DE-588)1203751575 (DE-588)1203751915 |
| author_facet | Ibrahim, Muntaser 1957- Rotimi, Charles N. 1957- |
| building | Verbundindex |
| bvnumber | BV045561886 |
| classification_rvk | WG 7000 |
| contents | Machine generated contents note: 1. Reflections on conceptualizing Africa for biological studies with a historical component: a small essay S.O. Y. Keita; 2. History and genetics in Africa: multidisciplinary efforts Shomarka Omar Y. Keita and Muntaser E. Ibrahim; 3. Disease, selection, and evolution in the African landscape Muntaser Ibrahim and Endashaw Bekele; 4. Genetic susceptibility to visceral leishmaniasis Hiba S. Mohamed, Muntaser E. Ibrahim and Jenefer M. Blackwell; 5. Genetics of infection in Sub-Saharan Africa: what can the study of Mendelian immunodeficiency disorders contribute? Melanie Newport; 6. Pharmacogenomics and infectious diseases in Africa: an evolutionary perspective Jennifer L. Baker, Daniel Shriner, Amy R. Bentley and Charles N. Rotimi; 7. A glimpse into pharmacogenomics in Africa Collet Dandara and Alice Matimba; 8. Genomics of cardiometabolic disorders in Sub-Saharan Africa Sally N. Adebamowo, Fasil Tekola-Ayele, Adebowale A. Adeyemo and Charles N. Rotimi; 9. Breast cancer in African populations Konduru S. Sastry and Lotfi Chouchane; 10. Socio-biological transition and cancer: prospects for Africa Sulma Mahmoud, Khalid O. Alfarouk, Ahmed M. Elhassan, Kamal Hamad and Muntaser E. Ibrahim; 11. The genetic epidemiology of orphan diseases in North Africa Lilia Romdhane, Olfa Messaoud, Rym Kefi, Afaf Tiar, Ahlem Amouri, Mourad Mokni, Neji Tebib, Mohamed Zghal, Abdelhamid Barakat, Ahmed Houmeida, Mariem Bozguiya, Mohamed Othman, Ghada El Qameh and Sonia Abdelhak; 12. Birth defects and genetic disease in Sub-Saharan Africa Ambroise Wonkam; 13. Neurogenetic disorders in Africa: hereditary spastic paraplegia: a case study Liena E. O. Elsayed, Ammar E. M. Ahmed and Giovanni Stevanin |
| ctrlnum | (OCoLC)1137832168 (DE-599)BVBBV045561886 |
| discipline | Biologie |
| format | Book |
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Breast cancer in African populations Konduru S. Sastry and Lotfi Chouchane; 10. Socio-biological transition and cancer: prospects for Africa Sulma Mahmoud, Khalid O. Alfarouk, Ahmed M. Elhassan, Kamal Hamad and Muntaser E. Ibrahim; 11. The genetic epidemiology of orphan diseases in North Africa Lilia Romdhane, Olfa Messaoud, Rym Kefi, Afaf Tiar, Ahlem Amouri, Mourad Mokni, Neji Tebib, Mohamed Zghal, Abdelhamid Barakat, Ahmed Houmeida, Mariem Bozguiya, Mohamed Othman, Ghada El Qameh and Sonia Abdelhak; 12. Birth defects and genetic disease in Sub-Saharan Africa Ambroise Wonkam; 13. Neurogenetic disorders in Africa: hereditary spastic paraplegia: a case study Liena E. O. Elsayed, Ammar E. M. Ahmed and Giovanni Stevanin</subfield></datafield><datafield tag="520" ind1="3" ind2=" "><subfield code="a">"The birthplace of modern humans, Africa, has the highest genetic diversity in the world, yet it remains vastly understudied. 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| id | DE-604.BV045561886 |
| illustrated | Illustrated |
| indexdate | 2024-12-06T17:00:49Z |
| institution | BVB |
| isbn | 9781107072022 1107072026 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-030945650 |
| oclc_num | 1137832168 |
| open_access_boolean | |
| owner | DE-703 DE-11 |
| owner_facet | DE-703 DE-11 |
| physical | xi, 338 Seiten Illustrationen, Diagramme |
| publishDate | 2020 |
| publishDateSearch | 2020 |
| publishDateSort | 2020 |
| publisher | Cambridge University Press |
| record_format | marc |
| series | Cambridge studies in biological and evolutionary anthropology |
| series2 | Cambridge studies in biological and evolutionary anthropology |
| spelling | The genetics of African populations in health and disease edited by Muntaser E. Ibrahim, Charles N. Rotimi Cambridge, United Kingdon ; New York, NY Cambridge University Press 2020 xi, 338 Seiten Illustrationen, Diagramme txt rdacontent n rdamedia nc rdacarrier Cambridge studies in biological and evolutionary anthropology [84] Machine generated contents note: 1. Reflections on conceptualizing Africa for biological studies with a historical component: a small essay S.O. Y. Keita; 2. History and genetics in Africa: multidisciplinary efforts Shomarka Omar Y. Keita and Muntaser E. Ibrahim; 3. Disease, selection, and evolution in the African landscape Muntaser Ibrahim and Endashaw Bekele; 4. Genetic susceptibility to visceral leishmaniasis Hiba S. Mohamed, Muntaser E. Ibrahim and Jenefer M. Blackwell; 5. Genetics of infection in Sub-Saharan Africa: what can the study of Mendelian immunodeficiency disorders contribute? Melanie Newport; 6. Pharmacogenomics and infectious diseases in Africa: an evolutionary perspective Jennifer L. Baker, Daniel Shriner, Amy R. Bentley and Charles N. Rotimi; 7. A glimpse into pharmacogenomics in Africa Collet Dandara and Alice Matimba; 8. Genomics of cardiometabolic disorders in Sub-Saharan Africa Sally N. Adebamowo, Fasil Tekola-Ayele, Adebowale A. Adeyemo and Charles N. Rotimi; 9. Breast cancer in African populations Konduru S. Sastry and Lotfi Chouchane; 10. Socio-biological transition and cancer: prospects for Africa Sulma Mahmoud, Khalid O. Alfarouk, Ahmed M. Elhassan, Kamal Hamad and Muntaser E. Ibrahim; 11. The genetic epidemiology of orphan diseases in North Africa Lilia Romdhane, Olfa Messaoud, Rym Kefi, Afaf Tiar, Ahlem Amouri, Mourad Mokni, Neji Tebib, Mohamed Zghal, Abdelhamid Barakat, Ahmed Houmeida, Mariem Bozguiya, Mohamed Othman, Ghada El Qameh and Sonia Abdelhak; 12. Birth defects and genetic disease in Sub-Saharan Africa Ambroise Wonkam; 13. Neurogenetic disorders in Africa: hereditary spastic paraplegia: a case study Liena E. O. Elsayed, Ammar E. M. Ahmed and Giovanni Stevanin "The birthplace of modern humans, Africa, has the highest genetic diversity in the world, yet it remains vastly understudied. With biomedical research increasingly focused on human variation, studying the large population size and number of mutations in African genomes could unravel the complexity of phenotypic traits underlying the biology of our species and hold huge potential for scientific and medical advances. An initial chapter 'conceptualizes Africa', providing relevant terminology. The first section covers genetic history and population structure. The next section looks at the genetic basis of common infectious diseases, such as leishmaniasis, malaria and tuberculosis, with a final part considering common non-communicable diseases, such as diabetes, hypertension, obesity, heart disease and cancer. Gene environment interaction under globalization and the burden of diseases of lifestyle are included. For researchers and graduate students in biological anthropology, genetic anthropology, human and population genetics, and public health"--Provided by publisher Genetische Variabilität (DE-588)4264352-1 gnd rswk-swf African Continental Ancestry Group / genetics Genetic Predisposition to Disease Communicable Diseases / genetics Noncommunicable Diseases Genetic Profile Africa Genetische Variabilität (DE-588)4264352-1 s DE-604 Ibrahim, Muntaser 1957- (DE-588)1203751575 edt Rotimi, Charles N. 1957- (DE-588)1203751915 edt Cambridge studies in biological and evolutionary anthropology [84] (DE-604)BV025266531 84 |
| spellingShingle | The genetics of African populations in health and disease Cambridge studies in biological and evolutionary anthropology Machine generated contents note: 1. Reflections on conceptualizing Africa for biological studies with a historical component: a small essay S.O. Y. Keita; 2. History and genetics in Africa: multidisciplinary efforts Shomarka Omar Y. Keita and Muntaser E. Ibrahim; 3. Disease, selection, and evolution in the African landscape Muntaser Ibrahim and Endashaw Bekele; 4. Genetic susceptibility to visceral leishmaniasis Hiba S. Mohamed, Muntaser E. Ibrahim and Jenefer M. Blackwell; 5. Genetics of infection in Sub-Saharan Africa: what can the study of Mendelian immunodeficiency disorders contribute? Melanie Newport; 6. Pharmacogenomics and infectious diseases in Africa: an evolutionary perspective Jennifer L. Baker, Daniel Shriner, Amy R. Bentley and Charles N. Rotimi; 7. A glimpse into pharmacogenomics in Africa Collet Dandara and Alice Matimba; 8. Genomics of cardiometabolic disorders in Sub-Saharan Africa Sally N. Adebamowo, Fasil Tekola-Ayele, Adebowale A. Adeyemo and Charles N. Rotimi; 9. Breast cancer in African populations Konduru S. Sastry and Lotfi Chouchane; 10. Socio-biological transition and cancer: prospects for Africa Sulma Mahmoud, Khalid O. Alfarouk, Ahmed M. Elhassan, Kamal Hamad and Muntaser E. Ibrahim; 11. The genetic epidemiology of orphan diseases in North Africa Lilia Romdhane, Olfa Messaoud, Rym Kefi, Afaf Tiar, Ahlem Amouri, Mourad Mokni, Neji Tebib, Mohamed Zghal, Abdelhamid Barakat, Ahmed Houmeida, Mariem Bozguiya, Mohamed Othman, Ghada El Qameh and Sonia Abdelhak; 12. Birth defects and genetic disease in Sub-Saharan Africa Ambroise Wonkam; 13. Neurogenetic disorders in Africa: hereditary spastic paraplegia: a case study Liena E. O. Elsayed, Ammar E. M. Ahmed and Giovanni Stevanin Genetische Variabilität (DE-588)4264352-1 gnd |
| subject_GND | (DE-588)4264352-1 |
| title | The genetics of African populations in health and disease |
| title_auth | The genetics of African populations in health and disease |
| title_exact_search | The genetics of African populations in health and disease |
| title_full | The genetics of African populations in health and disease edited by Muntaser E. Ibrahim, Charles N. Rotimi |
| title_fullStr | The genetics of African populations in health and disease edited by Muntaser E. Ibrahim, Charles N. Rotimi |
| title_full_unstemmed | The genetics of African populations in health and disease edited by Muntaser E. Ibrahim, Charles N. Rotimi |
| title_short | The genetics of African populations in health and disease |
| title_sort | the genetics of african populations in health and disease |
| topic | Genetische Variabilität (DE-588)4264352-1 gnd |
| topic_facet | Genetische Variabilität |
| volume_link | (DE-604)BV025266531 |
| work_keys_str_mv | AT ibrahimmuntaser thegeneticsofafricanpopulationsinhealthanddisease AT rotimicharlesn thegeneticsofafricanpopulationsinhealthanddisease |