Process development for the simultaneous microbial production of n-butanol and 1,3-propanediol:
This thesis comprises the development of a biotechnological process for the simultaneous production of n-butanol and 1,3-propanediol with Clostridium pasteurianum DSMZ 525, growing on substrates from renewable resources. The influence of carbon sources with different reductive states, iron availabil...
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| Format: | Abschlussarbeit Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Hamburg
2018
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| Schlagworte: | |
| Online-Zugang: | 11420/1669 Volltext Volltext Volltext Volltext |
| Zusammenfassung: | This thesis comprises the development of a biotechnological process for the simultaneous production of n-butanol and 1,3-propanediol with Clostridium pasteurianum DSMZ 525, growing on substrates from renewable resources. The influence of carbon sources with different reductive states, iron availability in the medium, redox active mediators and electro-bioreactors on metabolism and productivity were analyzed. For the recovery of inhibiting n-butanol, in situ gas stripping was implemented in the fermentation process and further optimized. Under the best conditions C. pasteurianum DSMZ 525 produced simultaneously 39 g/L BuOH and 53 g/L 1,3-PDO. Diese Arbeit umfasst die Entwicklung eines biotechnologischen Prozesses, zur Herstellung von n-Butanol und 1,3-Propandiol mit Clostridium pasteurianum DSMZ 525, unter der Verwendung von nachwachsenden Rohstoffen. Dabei wurde der Einfluss von verschiedenen Substraten, Eisenverfügbarkeit im Medium, redox-aktiven Substanzen und der Einsatz von Elektrobioreaktoren untersucht. Des Weiteren wurde der Effekt von in situ Gasstripping, zur Abtrennung des inhibierend wirkenden n-Butanols, analysiert und der Prozess optimiert. Unter den besten Kultivierungsbedingungen konnten 39 g/L n-Butanol und 53 g /L 1,3-PDO hergestellt werden |
| Beschreibung: | 1 Online-Ressource (XII, 144 Seiten) Diagramme |
| DOI: | 10.15480/882.1666 |
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| 520 | 3 | |a This thesis comprises the development of a biotechnological process for the simultaneous production of n-butanol and 1,3-propanediol with Clostridium pasteurianum DSMZ 525, growing on substrates from renewable resources. The influence of carbon sources with different reductive states, iron availability in the medium, redox active mediators and electro-bioreactors on metabolism and productivity were analyzed. For the recovery of inhibiting n-butanol, in situ gas stripping was implemented in the fermentation process and further optimized. Under the best conditions C. pasteurianum DSMZ 525 produced simultaneously 39 g/L BuOH and 53 g/L 1,3-PDO. | |
| 520 | 3 | |a Diese Arbeit umfasst die Entwicklung eines biotechnologischen Prozesses, zur Herstellung von n-Butanol und 1,3-Propandiol mit Clostridium pasteurianum DSMZ 525, unter der Verwendung von nachwachsenden Rohstoffen. Dabei wurde der Einfluss von verschiedenen Substraten, Eisenverfügbarkeit im Medium, redox-aktiven Substanzen und der Einsatz von Elektrobioreaktoren untersucht. Des Weiteren wurde der Effekt von in situ Gasstripping, zur Abtrennung des inhibierend wirkenden n-Butanols, analysiert und der Prozess optimiert. Unter den besten Kultivierungsbedingungen konnten 39 g/L n-Butanol und 53 g /L 1,3-PDO hergestellt werden | |
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| spelling | Prescher, Christin Verfasser (DE-588)1160403619 aut Process development for the simultaneous microbial production of n-butanol and 1,3-propanediol von Christin Prescher ; erster Gutachter: Prof. Dr. An-Ping Zeng, zweite Gutachterin: Prof. Dr.-Ing. Irina Smirnova Hamburg 2018 1 Online-Ressource (XII, 144 Seiten) Diagramme txt rdacontent c rdamedia cr rdacarrier Dissertation Technische Universität Hamburg-Harburg 2018 This thesis comprises the development of a biotechnological process for the simultaneous production of n-butanol and 1,3-propanediol with Clostridium pasteurianum DSMZ 525, growing on substrates from renewable resources. The influence of carbon sources with different reductive states, iron availability in the medium, redox active mediators and electro-bioreactors on metabolism and productivity were analyzed. For the recovery of inhibiting n-butanol, in situ gas stripping was implemented in the fermentation process and further optimized. Under the best conditions C. pasteurianum DSMZ 525 produced simultaneously 39 g/L BuOH and 53 g/L 1,3-PDO. Diese Arbeit umfasst die Entwicklung eines biotechnologischen Prozesses, zur Herstellung von n-Butanol und 1,3-Propandiol mit Clostridium pasteurianum DSMZ 525, unter der Verwendung von nachwachsenden Rohstoffen. Dabei wurde der Einfluss von verschiedenen Substraten, Eisenverfügbarkeit im Medium, redox-aktiven Substanzen und der Einsatz von Elektrobioreaktoren untersucht. Des Weiteren wurde der Effekt von in situ Gasstripping, zur Abtrennung des inhibierend wirkenden n-Butanols, analysiert und der Prozess optimiert. Unter den besten Kultivierungsbedingungen konnten 39 g/L n-Butanol und 53 g /L 1,3-PDO hergestellt werden lzar: la DNB Butanole (DE-588)4342781-9 gnd rswk-swf Bioraffinerie (DE-588)7742513-3 gnd rswk-swf Propandiole (DE-588)4344045-9 gnd rswk-swf Clostridium pasteurianum (DE-588)4224051-7 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Clostridium pasteurianum (DE-588)4224051-7 s Bioraffinerie (DE-588)7742513-3 s Butanole (DE-588)4342781-9 s Propandiole (DE-588)4344045-9 s DE-604 Zeng, An-Ping 1963- (DE-588)1138128279 dgs Smirnova, Irina (DE-588)1135633649 dgs Technische Universität Hamburg-Harburg (DE-588)2067664-5 dgg Technische Universität Hamburg-Harburg Institut für Bioprozess- und Biosystemtechnik (DE-588)10193909-7 oth 11420/1669 https://nbn-resolving.org/urn:nbn:de:gbv:830-88221152 Resolving-System kostenfrei Volltext https://doi.org/10.15480/882.1666 Verlag kostenfrei Volltext http://hdl.handle.net/11420/1669 Verlag kostenfrei Volltext http://tubdok.tub.tuhh.de/handle/11420/1669 kostenfrei Volltext |
| spellingShingle | Prescher, Christin Process development for the simultaneous microbial production of n-butanol and 1,3-propanediol Butanole (DE-588)4342781-9 gnd Bioraffinerie (DE-588)7742513-3 gnd Propandiole (DE-588)4344045-9 gnd Clostridium pasteurianum (DE-588)4224051-7 gnd |
| subject_GND | (DE-588)4342781-9 (DE-588)7742513-3 (DE-588)4344045-9 (DE-588)4224051-7 (DE-588)4113937-9 |
| title | Process development for the simultaneous microbial production of n-butanol and 1,3-propanediol |
| title_auth | Process development for the simultaneous microbial production of n-butanol and 1,3-propanediol |
| title_exact_search | Process development for the simultaneous microbial production of n-butanol and 1,3-propanediol |
| title_full | Process development for the simultaneous microbial production of n-butanol and 1,3-propanediol von Christin Prescher ; erster Gutachter: Prof. Dr. An-Ping Zeng, zweite Gutachterin: Prof. Dr.-Ing. Irina Smirnova |
| title_fullStr | Process development for the simultaneous microbial production of n-butanol and 1,3-propanediol von Christin Prescher ; erster Gutachter: Prof. Dr. An-Ping Zeng, zweite Gutachterin: Prof. Dr.-Ing. Irina Smirnova |
| title_full_unstemmed | Process development for the simultaneous microbial production of n-butanol and 1,3-propanediol von Christin Prescher ; erster Gutachter: Prof. Dr. An-Ping Zeng, zweite Gutachterin: Prof. Dr.-Ing. Irina Smirnova |
| title_short | Process development for the simultaneous microbial production of n-butanol and 1,3-propanediol |
| title_sort | process development for the simultaneous microbial production of n butanol and 1 3 propanediol |
| topic | Butanole (DE-588)4342781-9 gnd Bioraffinerie (DE-588)7742513-3 gnd Propandiole (DE-588)4344045-9 gnd Clostridium pasteurianum (DE-588)4224051-7 gnd |
| topic_facet | Butanole Bioraffinerie Propandiole Clostridium pasteurianum Hochschulschrift |
| url | 11420/1669 https://nbn-resolving.org/urn:nbn:de:gbv:830-88221152 https://doi.org/10.15480/882.1666 http://hdl.handle.net/11420/1669 http://tubdok.tub.tuhh.de/handle/11420/1669 |
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