Cell volume regulation:
Gespeichert in:
Weitere Verfasser: | , , |
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Format: | Buch |
Sprache: | English |
Veröffentlicht: |
London, United Kingdom ; San Diego, CA, United States ; Cambridge, MA, United States ; Oxford, United Kingdom
Academic Press
2018
|
Ausgabe: | First edition |
Schriftenreihe: | Current topics in membranes
volume 81 |
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | xvii, 496 Seiten Illustrationen |
ISBN: | 9780128154564 |
Internformat
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245 | 1 | 0 | |a Cell volume regulation |c edited by Irena Levitan (Professor of medicine, pharmacology and bioengineering, University of Illinois at Chicago), Eric Delpire (Professor of anesthesiology, molecular physiology & biophysics, Vanderbilt University School of Medicine), Hector Rasgado-Flores (Professor of physiology and biophysics, Rosalind Franklin University of Medicine and Science, North Chicago, USA) |
250 | |a First edition | ||
264 | 1 | |a London, United Kingdom ; San Diego, CA, United States ; Cambridge, MA, United States ; Oxford, United Kingdom |b Academic Press |c 2018 | |
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Datensatz im Suchindex
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adam_text | CONTENTS
Contributors xi
The journey from discovering cell volume regulation of euryhaline fish to
the identification of key mechanisms of cell volume homeostasis xv
Section 1
General Principles of Cell Volume Regulation
1. Water Homeostasis and Cell Volume Maintenance and Regulation 3
Eric Delpire and Kenneth B. Gagnon
1. Introduction 4
2. Whole Body Water Homeostasis 6
3. Cell Volume Homeostasis 12
Acknowledgments 40
References 40
2. Search for Upstream Cell Volume Sensors: The Role of Plasma
Membrane and Cytoplasmic Hydrogel S3
Sergei N. Orlov, Aleksandra Shiyan, Francis Boudreault, Olga Ponomarchuk,
and Ryszard Grygorczyk
1. Introduction 54
2. Cell Volume-Sensing by the Plasma Membrane 55
3. Cell Volume Sensing by the Cytoplasm 65
4. Delayed Volume Sensors: Role of Elevated [Na+]/[K+]j Ratio 69
5. Conclusions and Perspective 73
Acknowledgments 75
References 75
3. Cytoskeletal Contribution to Cell Stiffness Due to
Osmotic Swelling; Extending the Donnan Equilibrium 83
Pei-Chuan Chao, Mettupalayam Sivaselvan, and Frederick Sachs
1. Introduction 84
2. Modeling 85
3. Equilibrium of Chemical Potential and Osmotic Pressure
Due to Fixed Charge 86
v
VI
Contents
4. Mechanical Equilibrium 87
5. Numerical Results 89
6. Summary 91
7. Discussion 91
References 94
4. Membrane Stiffening in Osmotic Swelling: Analysis of
Membrane Tension and Elastic Modulus 97
Manuela A.A. Ayee and Irena Levitan
1. Introduction 98
2. Membrane Tension 102
3. Elastic Properties 113
4. Conclusions 117
Acknowledgments 118
References 118
5. Molecular Identities and ATP Release Activities of Two
Types of Volume-Regulatory Anion Channels, VSOR and Maxi-CI 125
Yasunobu Okada# Toshiaki Okada, Md. Rafiqul Islam,
and Ravshan Z. Sabirov
1. Introduction 126
2. Two Types of Volume-Regulatory Anion Channels: VSOR and Maxi-CI 127
3. Molecular Identities of VSOR 132
4. Molecular Identities of Maxi-CI 145
5. ATP Release Activities of VSOR and Maxi-C! 152
6. Conclusions and Future Directions 158
Acknowledgments 159
References 160
6. Molecular Biology and Physiology of Volume-Regulated
Anion Channel (VRAC) 177
James Osei-Owusu, Junhua Yang, Maria del Carmen Vitery,
and Zhaozhu Qiu
1. Introduction 178
2. LRRC8 Heteromers as VRAC 180
3. Physiological Role of SWELL1 and VRAC 187
4. Future Studies of VRAC 192
Acknowledgments 196
References 196
Contents vii
Section 2
Regulation of Intracellular Chloride and
Water Homeostasis
7. Role of WNK Kinases in the Modulation of Cell Volume 207
Paola de los Heros, Diana Pacheco-Alvarez, and Gerardo Gamba
1. Introduction 208
2. Principles of Cell Volume Regulation 208
3. With No Lysine Kinases (WNKs) 219
4. The WNK Kinases as Intracellular Chloride Sensors 222
5. WNKs and Cell Volume Regulation 227
References 229
8. Intracellular Macromolecules in Cell Volume Control and
Methods of Their Quantification 237
Michael A. Model and Jonathan C. Petruccelli
1. Introduction 238
2. The Components of Ceil Volume and the Main Relationships 240
3. Methods for Measurement of W, Ay, and A$ (Non-QPI) 245
4. Quantitative Phase Imaging (QPI) 251
5. Biological Questions 263
6. Conclusion 273
Acknowledgments 274
References 274
Section 3
Cell Volume Regulation in the Airways
9. Slippery When Wet: Airway Surface Liquid Homeostasis and
Mucus Hydration 293
Megan J. Webster and Robert Tarran
1. Introduction 294
2. Airway Surface Liquid (ASL) Composition 299
3. Airway Surface Liquid Volume Regulation 300
4. pH Homeostasis of the ASL 316
5. CF Lung Disease 319
6. Conclusions 324
References 324
viii
Contents
10. Physiology of the Gut: Experimental Models for Investigating
Intestinal Fluid and Electrolyte Transport 337
Isha Dey and Neil A. Bradbury
1. Introduction 338
2. Epithelial Ion and Fluid Secretion 343
3. Intestinal Ion and Fluid Transport 348
4. Model Systems for Studying Intestinal Ion Transport 352
5. A Swell Ing Assay 363
6. Summary 370
References 371
Section 4
Cell Volume Regulation in the Brain
11. Cell Volume Control in Healthy Brain and Neuropathologies 385
Corinne S. Wilson and Alexander A. Mongin
1. Common and Unique Aspects of Osmotic Balance Within the CNS 387
2. RVD in the CNS Cells 395
- 3. RV! in the CNS Cells 404
4. Celt Volume Changes During Normal Brain Functioning 405
5. A Special Case for Astrocytic Swelling and Cell Volume Control 409
6. Failure of Cell Volume Control in Brain Pathologies 415
7. VRAC as a Villain in Neuropathoiogies 427
8. The Evolving Understanding of VRAC Identity: Progress and
Perspectives 430
Acknowledgments 436
References 436
12. Cytotoxic Swelling of Sick Excitable Cells - Impaired ion
Homeostasis and Membrane Tension Homeostasis in
Muscle and Neuron 457
Catherine E. Morris
1. Membrane injury. Na+-Loading. Swelling Death. Or Not? 459
2. Membrane Tension Homeostasis and Membrane Fragility 461
3. Safeguarding the Bilayer - Tension Buffering 465
4. Mammalian Neuron Os mo resistivity Revisited 469
5. Donnan the Elephant (in the Sick Excitable Room) 470
Contents
IX
6. Cytotoxic Swelling of Skeletal Muscle 472
7. Excitotoxic Insults Stiffen Neurons. Then They Swell, Bleb, Soften, Die 476
8. Cytotoxic Swelling of Neurons 478
9. Modeling Excitotoxic Swelling in Neurons 480
10. Mechanistic Model for Excitotoxic Neuronal Swelling During SD 485
11. Conclusion: IH and MTH Working Together 486
References 489
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indexdate | 2024-07-10T08:19:57Z |
institution | BVB |
isbn | 9780128154564 |
language | English |
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spelling | Cell volume regulation edited by Irena Levitan (Professor of medicine, pharmacology and bioengineering, University of Illinois at Chicago), Eric Delpire (Professor of anesthesiology, molecular physiology & biophysics, Vanderbilt University School of Medicine), Hector Rasgado-Flores (Professor of physiology and biophysics, Rosalind Franklin University of Medicine and Science, North Chicago, USA) First edition London, United Kingdom ; San Diego, CA, United States ; Cambridge, MA, United States ; Oxford, United Kingdom Academic Press 2018 xvii, 496 Seiten Illustrationen txt rdacontent n rdamedia nc rdacarrier Current topics in membranes volume 81 Zellvolumen (DE-588)4214206-4 gnd rswk-swf Osmoregulation (DE-588)4172911-0 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Zellvolumen (DE-588)4214206-4 s Osmoregulation (DE-588)4172911-0 s b DE-604 Levitan, Irena (DE-588)1170911080 edt Delpire, Eric (DE-588)1170911560 edt Rasgado-Flores, Hector (DE-588)1170911765 edt Current topics in membranes volume 81 (DE-604)BV036839511 81 Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030889914&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Cell volume regulation Current topics in membranes Zellvolumen (DE-588)4214206-4 gnd Osmoregulation (DE-588)4172911-0 gnd |
subject_GND | (DE-588)4214206-4 (DE-588)4172911-0 (DE-588)4143413-4 |
title | Cell volume regulation |
title_auth | Cell volume regulation |
title_exact_search | Cell volume regulation |
title_full | Cell volume regulation edited by Irena Levitan (Professor of medicine, pharmacology and bioengineering, University of Illinois at Chicago), Eric Delpire (Professor of anesthesiology, molecular physiology & biophysics, Vanderbilt University School of Medicine), Hector Rasgado-Flores (Professor of physiology and biophysics, Rosalind Franklin University of Medicine and Science, North Chicago, USA) |
title_fullStr | Cell volume regulation edited by Irena Levitan (Professor of medicine, pharmacology and bioengineering, University of Illinois at Chicago), Eric Delpire (Professor of anesthesiology, molecular physiology & biophysics, Vanderbilt University School of Medicine), Hector Rasgado-Flores (Professor of physiology and biophysics, Rosalind Franklin University of Medicine and Science, North Chicago, USA) |
title_full_unstemmed | Cell volume regulation edited by Irena Levitan (Professor of medicine, pharmacology and bioengineering, University of Illinois at Chicago), Eric Delpire (Professor of anesthesiology, molecular physiology & biophysics, Vanderbilt University School of Medicine), Hector Rasgado-Flores (Professor of physiology and biophysics, Rosalind Franklin University of Medicine and Science, North Chicago, USA) |
title_short | Cell volume regulation |
title_sort | cell volume regulation |
topic | Zellvolumen (DE-588)4214206-4 gnd Osmoregulation (DE-588)4172911-0 gnd |
topic_facet | Zellvolumen Osmoregulation Aufsatzsammlung |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030889914&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
volume_link | (DE-604)BV036839511 |
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