Die Makrophagenpolarisation in apikalen Granulomen, radikulären Zysten und follikulären Zysten:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Abschlussarbeit Buch |
| Sprache: | German |
| Veröffentlicht: |
Erlangen ; Nürnberg
2018
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Inhaltsverzeichnis |
| Beschreibung: | 79 Seiten Illustrationen, Diagramme 21 cm |
Internformat
MARC
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| 245 | 1 | 0 | |a Die Makrophagenpolarisation in apikalen Granulomen, radikulären Zysten und follikulären Zysten |c vorgelegt von Lena Marsing |
| 264 | 1 | |a Erlangen ; Nürnberg |c 2018 | |
| 300 | |a 79 Seiten |b Illustrationen, Diagramme |c 21 cm | ||
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| 502 | |b Dissertation |c Friedrich-Alexander-Universität Erlangen-Nürnberg |d 2018 | ||
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Datensatz im Suchindex
| _version_ | 1804179303896711168 |
|---|---|
| adam_text | 1. ZUSAM M EN
FASSUNG.....................................................................................................................1
1.1 HINTERGRUND UND
ZIELE............................................................................................................
1
1.2 MATERIAL UND M
ETHODEN.........................................................................................................2
1.3
ERGEBNISSE.................................................................................................................................2
1.4
SCHLUSSFOLGERUNG...................................................................
3
2. S U M M A RY
.......................................................................................................................................
3
2.1 BACKGROUND AND
AIMS.............................................................................................................
3
2.2 MATERIALS AND
METHODS..........................................................................................................4
2.3
RESULTS.......................................................................................................................................
4
2.4 PRACTICAI
CONCLUSION.................................................................................................................5
3.
EINLEITUNG.......................................................................................................................................
5
3.1 STAND DER
FORSCHUNG..............................................................................................................
7
3.1.1 AETIOPATHOGENESE PERIAPIKALER LAESIONEN
....................................................................
7
3.1.1.1 DAS APIKALE
GRANULOM............................................................................................
9
3.1.1.2 DIE RADIKULAERE
ZYSTE.............................................................................................
11
3.1.1.3
ZYSTENENTSTEHUNG.................................................................................................12
3.1.1.3.1 DIE
MALASSEZ-EPITHELRESTE...........................................................................
12
3.1.1.3.2 PROLIFERATION EPITHELIALER ZELLEN IN DER APIKALEN PARODONTITIS
..............
13
3.1.1.3.3 DIE ENTSTEHUNG DER RADIKULAEREN ZYSTE AUS DER APIKALEN
PARODONTITIS -
VERSCHIEDENE
THEORIEN..................................................................................................14
3.1.2 DIE FOLLIKULAERE
ZYSTE.....................................................................................................
15
3.1.3
MAKROPHAGEN.................................................................................................................16
3.1.3.1 M L-M AKRO
PHAGEN.................................................................................................17
3.1.3.2 M 2-M
AKROPHAGEN.................................................................................................17
3.1.3.3
MAKROPHAGENMARKER...........................................................................................18
3.2 ZIEL DER ARBEIT UND
FRAGESTELLUNG......................................................................................
19
4. M A TERIA L UND M E TH O D E
...........................................................................................................20
4.1 M
ATERIAL..............................................................................................................................
20
4.1.1 G
ERAETE............................................................... 20
4.1.2
VERBRAUCHSMATERIALIEN................................................................................................
21
4.1.3
REAGENZIEN.....................................................................................................................
22
4.1.4 PUFFER UND
LOESUNGEN.....................................................................................................23
4.1.5
ANTIKOERPER.......................................................................................................................
24
4.1.6
SOFTWARE..........................................................................................................................
25
4.2 M E TH O D E
.............................................................................................................................25
4.2.1 PATIENTEN- UND
PROBENAUSWAHL.................................................................................
25
4.2.2 HERSTELLUNG DER TISSUE MICROARRAYS
(TMAS).............................................................26
4.2.2.1 DIE
TMA-TECHNOLOGIE............................................................................................26
4.2.2.2 ERSTELLEN DES
TMA-PARAFFINBLOCKS......................................................................28
4.2.3 HERSTELLUNG DER
PARAFFINSCHNITTE................................................................................
29
4.2.4 VORBEREITUNG DER PARAFFINSCHNITTE FUER DIE IMMUNHISTOCHEMISCHE
FAERBUNG.... 30
4.2.5 DIE IMMUNHISTOCHEMISCHE NACHWEISREAKTION
........................................................
30
4.2.5.1 DAS PRINZIP DER LSAB-METHODE
..........................................................................
30
4.2.5.2
FAERBEVORGANG.........................................................................................................
32
4.2.6 IMMUNHISTOCHEMISCHE
ANALYSE.................................................................................
33
4.2.7 STATISTISCHE
ANALYSE.......................................................................................................34
5.
ERGEBNISSE...................................................................................................................................35
5.1 DESKRIPTIVE STATISTIK - MAKROPHAGENZELLZAHL
..................................................................
35
5.1.1
CD68.................................................................................................................................
35
5.1.2 C D LLC
...............................................................................................................................38
5.1.3
CD163...............................................................................................................................41
5.1.4
MRC1................................................................................................................................44
5.2 DESKRIPTIVE STATISTIK -
MAKROPHAGENPOLARISIERUNG........................................................
47
5.2.1
ML-POLARISIERUNG...........................................................................................................
47
5.2.1.1 C D LLC /C D 6 8
...........................................................................................................
47
5.2.1.2 C D LLC /C D 1 6 3
.........................................................................................................
49
5.2.1.3 C D LLC /M R C
L..........................................................................................................
50
5.2.2
M2-POLARISIERUNG............................................................................................................52
5.2.2.1
CD163/CD68...........................................................................................................
52
5.2.2.2
MRC1/CD68.............................................................................................................53
5.2.2.3
CD163/CD11C.........................................................................................................
55
6.
DISKUSSION....................................................................................................................................
57
7.
LITERATURVERZEICHNIS.................................................................................................................
64
8.
ABBILDUNGSVERZEICHNIS............................................................................................................
76
9. TABELLENVERZEICHNIS
10.
ABKUERZUNGSVERZEICHNIS.......................................................................................................78
11.
DANKSAGUNG............................................................................................................................79
|
| any_adam_object | 1 |
| author | Marsing, Lena |
| author_GND | (DE-588)1176069209 |
| author_facet | Marsing, Lena |
| author_role | aut |
| author_sort | Marsing, Lena |
| author_variant | l m lm |
| building | Verbundindex |
| bvnumber | BV045422892 |
| ctrlnum | (OCoLC)1090119896 (DE-599)DNB1169970850 |
| discipline | Medizin |
| format | Thesis Book |
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| genre_facet | Hochschulschrift |
| id | DE-604.BV045422892 |
| illustrated | Illustrated |
| indexdate | 2024-07-10T08:17:44Z |
| institution | BVB |
| language | German |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-030808744 |
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| physical | 79 Seiten Illustrationen, Diagramme 21 cm |
| publishDate | 2018 |
| publishDateSearch | 2018 |
| publishDateSort | 2018 |
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| spelling | Marsing, Lena Verfasser (DE-588)1176069209 aut Die Makrophagenpolarisation in apikalen Granulomen, radikulären Zysten und follikulären Zysten vorgelegt von Lena Marsing Erlangen ; Nürnberg 2018 79 Seiten Illustrationen, Diagramme 21 cm txt rdacontent n rdamedia nc rdacarrier Dissertation Friedrich-Alexander-Universität Erlangen-Nürnberg 2018 (DE-588)4113937-9 Hochschulschrift gnd-content B:DE-101 application/pdf http://d-nb.info/1169970850/04 Inhaltsverzeichnis DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030808744&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Marsing, Lena Die Makrophagenpolarisation in apikalen Granulomen, radikulären Zysten und follikulären Zysten |
| subject_GND | (DE-588)4113937-9 |
| title | Die Makrophagenpolarisation in apikalen Granulomen, radikulären Zysten und follikulären Zysten |
| title_auth | Die Makrophagenpolarisation in apikalen Granulomen, radikulären Zysten und follikulären Zysten |
| title_exact_search | Die Makrophagenpolarisation in apikalen Granulomen, radikulären Zysten und follikulären Zysten |
| title_full | Die Makrophagenpolarisation in apikalen Granulomen, radikulären Zysten und follikulären Zysten vorgelegt von Lena Marsing |
| title_fullStr | Die Makrophagenpolarisation in apikalen Granulomen, radikulären Zysten und follikulären Zysten vorgelegt von Lena Marsing |
| title_full_unstemmed | Die Makrophagenpolarisation in apikalen Granulomen, radikulären Zysten und follikulären Zysten vorgelegt von Lena Marsing |
| title_short | Die Makrophagenpolarisation in apikalen Granulomen, radikulären Zysten und follikulären Zysten |
| title_sort | die makrophagenpolarisation in apikalen granulomen radikularen zysten und follikularen zysten |
| topic_facet | Hochschulschrift |
| url | http://d-nb.info/1169970850/04 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030808744&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT marsinglena diemakrophagenpolarisationinapikalengranulomenradikularenzystenundfollikularenzysten |
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