Myeloid cells in health and disease: a synthesis
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Washington, DC
ASM Press
[2017]
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | xxxiii, 892 pages illustrations (some color) 29 cm |
| ISBN: | 9781555819187 1555819184 |
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| 245 | 1 | 0 | |a Myeloid cells in health and disease |b a synthesis |c edited by Siamon Gordon, Emeritus Professor of Cellular Pathology, Sir William Dunn School of Pathology, Oxford, United Kingdom |
| 264 | 1 | |a Washington, DC |b ASM Press |c [2017] | |
| 264 | 4 | |c © 2017 | |
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| 500 | |a Includes bibliographical references and index | ||
| 650 | 4 | |a Bone marrow cells | |
| 650 | 4 | |a Leucocytes | |
| 650 | 4 | |a Granulocytes | |
| 650 | 4 | |a Monocytes | |
| 650 | 4 | |a Phagocytes | |
| 650 | 4 | |a Hematopoietic stem cells | |
| 650 | 4 | |a Cellular immunity | |
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Datensatz im Suchindex
| _version_ | 1804179291581186048 |
|---|---|
| adam_text | Contents
Contributors xiii
Preface xxvii
Acknowledgments xxxi
About the Editor xxxiii
I. INTRODUCTION AND HISTORY
1. Paul Ehrlich and the Early History of Granulocytes 3
A. Barry Kay
2. The Phagocyte, Metchnikoff, and the Foundation
of Immunology 17
Giuseppe Teti, Carmelo Biondo, and Concetta Beninati
3. Growth and Differentiation Factors 31
Donald Metcalf
Feat. In Memoriam by Nicos A. Nicola
II. GENERAL ASPECTS
4. Evolution of Myeloid Cells 45
Daniel R. Barreda, Harold R. Neely, and Martin F. Flajnik
5. Advances in Myeloid-Like Cell Origins and Functions in the Model
Organism Drosophila melanogaster 59
Laure El Chamy, Nicolas Matt, and Jean-Marc Reichhart
Contents
via
6. Monocyte, Macrophage, and Dendritic Cell Development:
the Human Perspective 79
Matthew Collin and Venetia Bigley
7. Myeloid Cell Turnover and Clearance 99
William J. Janssen, Donna L. Bratton, Claudia V. Jakubzick,
and Peter M. Henson
III. SPECIALIZATION
8. Transcriptional Regulation and Macrophage Differentiation 119
David A. Hume, Kim M. Summers, and Michael Rehli
9. Murine Monocytes: Origins, Subsets, Fates, and Functions 141
Alexander Mildner, Goran Marinkovic, and Steffen Jung
10. Dendritic Cells in the Immune System: History, Lineages, Tissues,
Tolerance, and Immunity 155
Jonathan M. Austyn
11. Antigen Processing and Presentation Mechanisms
in Myeloid Ceils 209
Paul A. Roche and Peter Cres swell
12. Microglia 225
V. Hugh Perry
13. Osteoclasts—Key Players in Skeletal Health and Disease 235
Deborah Veis Novack and Gabriel Mbalaviele
14. The Regulatory Function of Eosinophils 257
Ting Wen and Marc E. Rothenberg
IY. RECRUITMENT, INFLAMMATION, AND REPAIR
15. Intravital Imaging of Myeloid Cells: Inflammatory Migration and
Resident Patrolling 273
Paul Kubes and Justin F. Deniset
16. Multifaceted Functions of NOD-Like Receptor Proteins in Myeloid
Cells at the Intersection of Innate and Adaptive Immunity 295
Thomas A. Kufer, Giulia Nigro, and Philippe J. Sansoneth
17. Inflammasomes in Myeloid Cells: Warriors Within 305
Sushmita Jiia, W. June Brickey, andJenny Pan-Yun Ting
18. Inflammation—a Critical Appreciation of the Role
of Myeloid Cells 325
Asif J. Iqbal, Edward A. Fisher, and David R. Greaves
19. Lipid Mediators in Inflammation 343
Melanie Bennett and Derek W. Gilroy
Contents
20. Macrophage Proresolving Mediators—the When and Where 367
Jesmond Dalli and Charles Serhan
21. Myeloid Cells in Cutaneous Wound Repair 385
Jenna L. Cash and Paul Martin
V. RECOGNITION, SIGNALING, AND GENE EXPRESSION
22. The Role and Function of Fey Receptors on Myeloid Cells 407
Stylianos Bournazos, Taia T. Wang, and Jeffrey V. Ravetch
23. Complement Receptors in Myeloid Cell Adhesion and
Phagocytosis 429
Michael L. Dustin
24. Toll-Like Receptor Signaling and Its Inducible Proteins 447
Takashi Satoh and Shizuo Akira
25. Lectin Receptors Expressed on Myeloid Cells 455
Gordon D. Brown and Paul R. Crocker
26. G Protein-Coupled Receptors in Macrophages 485
Hsi-Hsien Lin and Martin Stacey
27. Molecular Mechanisms of Phagosome Formation 507
Valentin Jaumouillt and Sergio Grinstein
28. Role of the Cytoskeleton in Myeloid Cell Function 527
Noah Fine, Samira Khaliq, Siavash Hassanpour,
and Michael Glogauer
29. Coordinated Regulation of Signaling Pathways during
Macrophage Activation 543
Toby Lawrence
30. Genome-Wide Approaches to Defining Macrophage Identity
and Function 553
Gregory J. Fonseca, Jason S. Seidman, and Christopher K. Glass
31. Epigenetic Regulation of Myeloid Cells 571
Lionel B. Ivashkiv and Sung Ho Park
VI. SECRETION AND DEFENSE
32. Secretion from Myeloid Cells: Secretory Lysosomes 593
Gillian M. Griffiths
33. The NADPH Oxidase and Microbial Killing by Neutrophils,
With a Particular Emphasis on the Proposed Antimicrobial
Role of Myeloperoxidase within the Phagocytic Vacuole 599
Adam P. Levine and Anthony W. Segal
Contents
X
34. Evolution of Cell-Autonomous Effector Mechanisms in
Macrophages versus Non-Immune Cells 615
Ryan G. Gaudet, Clinton J. Bradfield, and John D. MacMicking
35. Anti-TNF Therapy 637
Irina Udalova, Claudia Monaco, Jagdeep Nanchahal,
and Marc Feldmann
36. Metalloproteinases: a Functional Pathway for
Myeloid Cells 649
Jonathan Chou, Matilda F. Chan, and Zena Werb
VII. IMMUNOREGULATION AND INFECTION
37. Interplay between Myeloid Cells and Humoral
Innate Immunity 661
Sébastien Jaillon, Eduardo Bonavita, Cecilia Garlanda,
and Alberto Mantovani
38. Adaptive Characteristics of Innate Immune Responses
in Macrophages 679
Rob J. W. Arts and Mihai G. Netea
39. Intestinal Mononuclear Phagocytes in Health and Disease 687
Theodore J. Sanders, Ulf Yrlid, and Kevin J. Maloy
40. Strategies Used by Bacteria to Grow in Macrophages 701
Gabriel Mitchell, Chen Chen, and Daniel A. Portnoy
41. Mechanisms of Defense against Intracellular Pathogens Mediated
by Human Macrophages 727
Barry R. Bloom and Robert L. Modlin
42. Myeloid Cells in Asthma 739
Bart N. Lambrecht, Emma K. Persson, and Hamida Hammad
43. Myeloid Cell Phenotypes in Susceptibility and Resistance to
Helminth Parasite Infections 759
Rick M. Maizels and James P. Hewitson
44. Induction of Immunological Tolerance as
a Therapeutic Procedure 771
Herman Waldmann, Duncan Howie, and Stephen Cobb old
VIII. METABOLIC AND MALIGNANT DISEASE
45. Glutathione and Glutathione Transferase Omega 1 as Key
Posttranslational Regulators in Macrophages 789
Mark M. Hughes, Anne F. McGettrick, and Luke A.J. O’Neill
Contents
XX
46. Macrophages and Iron Metabolism 803
Tomas Ganz
47. Mechanisms of Myeloid Cell Modulation
of Atherosclerosis 813
Filip K. Swirski, Matthias Nahrendorf, and Peter Libby
48. Macrophages in Endocrine Glands, with Emphasis
on Pancreatic Islets 825
Emil R. Unanue
49. Tumor-Induced Myeloid-Derived Suppressor Cells 833
Francesco De Sanctis, Vincenzo Bronte, and Stefano Ugel
50. Myeloid Cell Origins, Differentiation, and Clinical
Implications 857
Kipp Weiskopf, Peter J. Schnorr, Wendy W. Pang, Mark P. Chao,
Akanksha Chhabra, Jun Seita, Mingye Feng, and Irving L. Weissman
Index 877
The structure, functions, and interactions of myeloid
cells have long been the focus of research and
therapeutics development. Yet, much more remains to
be discovered about the complex web of relationships
that makes up the immune systems of animals. Scientists
today are applying genome-wide analyses, single-cell
methods, gene editing, and modern imaging techniques
to reveal new subclasses of differentiated myeloid cells,
new receptors and cytokines, and important interactions
among immune cells.
In Myeloid Cells in Health end Disease: A Synthesis,
Editor Siamon Gordon has assembled an international
team of esteemed scientists to provide their perspectives
of myeloid cells during innate and adaptive immunity.
The book begins by presenting the foundational research
of Paul Ehrlich, Elie Metchnikoff, and Donald Metcalf. The
following chapters discuss evolution and the life cycles
of myeloid cells; specific types of differentiated myeloid
cells, including macrophage differentiation; and antigen
processing and presentation. The rest of the book is
organized by broad topics in immunology, including
• the recruitment of myeloid and other immune cells
following microbial infection.
• the role of myeloid cells in the inflammation process
and the repair of damaged tissue
• the vast arsenal of myeloid cell secretory molecules,
including metalloproteinases, tumor necrosis factor,
histamine, and perforin
• receptors and downstream signaling pathways that
are activated following ligand-receptor binding
• roles of myeloid cells during microbial and parasite
infections
* contributions of myeloid cells in atherosclerosis
• myeloid-derived suppressor cells in tumor develop-
ment and cancer
Myeloid Cells In Health and Disease: A Synthesis will
benefit graduate students and researchers in immunology,
hematology, microbial pathogenesis, infectious disease,
pathology, and pharmacology. Established scientists and
physicians in these and related fields will enjoy the book’s
rich history of myeloid cell research and suggestions for
future research directions and potential therapies,
siamon GORDON received his medical
degree from the University of Cape
Town. After an introduction to immu-
nology at the Wright Fleming Institute
in London, Dr. Gordon moved to the
Rockefeller University, first as a postdoc
and then as a doctoral student. His thesis
project used macrophage-melanoma cell
heterokaryons to study cellular differentiation. Dr. Gordon
continued researching macrophage immunobiology for the
remainder of his academic career, first at Rockefeller, then
at the University of Oxford, retiring as Glaxo Wellcome
Professor of Cellular Pathology at the Sir William Dunn
School of Pathology in 2008. He was elected to fellow-
ship of the Royal Society in 2007. After retiring from his
academic post, he spent a year at the National Institutes
of Health. He has continued to be active in promoting
research in South Africa, as well as initiating an AIDS
education project there.
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| spelling | Myeloid cells in health and disease a synthesis edited by Siamon Gordon, Emeritus Professor of Cellular Pathology, Sir William Dunn School of Pathology, Oxford, United Kingdom Washington, DC ASM Press [2017] © 2017 xxxiii, 892 pages illustrations (some color) 29 cm txt rdacontent n rdamedia nc rdacarrier Includes bibliographical references and index Bone marrow cells Leucocytes Granulocytes Monocytes Phagocytes Hematopoietic stem cells Cellular immunity Knochenmarkzelle (DE-588)4123534-4 gnd rswk-swf Myelozyt (DE-588)4309927-0 gnd rswk-swf Myelozyt (DE-588)4309927-0 s DE-604 Knochenmarkzelle (DE-588)4123534-4 s Gordon, Siamon 1938- (DE-588)1133290450 edt Erscheint auch als Online-Ausgabe Myeloid cells in health and disease Washington, DC : ASM Press, [2017] 978-1-55581-919-4 Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030801993&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030801993&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Myeloid cells in health and disease a synthesis Bone marrow cells Leucocytes Granulocytes Monocytes Phagocytes Hematopoietic stem cells Cellular immunity Knochenmarkzelle (DE-588)4123534-4 gnd Myelozyt (DE-588)4309927-0 gnd |
| subject_GND | (DE-588)4123534-4 (DE-588)4309927-0 |
| title | Myeloid cells in health and disease a synthesis |
| title_auth | Myeloid cells in health and disease a synthesis |
| title_exact_search | Myeloid cells in health and disease a synthesis |
| title_full | Myeloid cells in health and disease a synthesis edited by Siamon Gordon, Emeritus Professor of Cellular Pathology, Sir William Dunn School of Pathology, Oxford, United Kingdom |
| title_fullStr | Myeloid cells in health and disease a synthesis edited by Siamon Gordon, Emeritus Professor of Cellular Pathology, Sir William Dunn School of Pathology, Oxford, United Kingdom |
| title_full_unstemmed | Myeloid cells in health and disease a synthesis edited by Siamon Gordon, Emeritus Professor of Cellular Pathology, Sir William Dunn School of Pathology, Oxford, United Kingdom |
| title_short | Myeloid cells in health and disease |
| title_sort | myeloid cells in health and disease a synthesis |
| title_sub | a synthesis |
| topic | Bone marrow cells Leucocytes Granulocytes Monocytes Phagocytes Hematopoietic stem cells Cellular immunity Knochenmarkzelle (DE-588)4123534-4 gnd Myelozyt (DE-588)4309927-0 gnd |
| topic_facet | Bone marrow cells Leucocytes Granulocytes Monocytes Phagocytes Hematopoietic stem cells Cellular immunity Knochenmarkzelle Myelozyt |
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