The rewiring brain: a computational approach to structural plasticity in the adult brain
The adult brain is not as hard-wired as traditionally thought. By modifying their small- or large-scale morphology, neurons can make new synaptic connections or break existing ones (structural plasticity). Structural changes accompany memory formation and learning, and are induced by neurogenesis, n...
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
London
Academic Press
2017
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| Schlagworte: | |
| Online-Zugang: | FAW01 Volltext |
| Zusammenfassung: | The adult brain is not as hard-wired as traditionally thought. By modifying their small- or large-scale morphology, neurons can make new synaptic connections or break existing ones (structural plasticity). Structural changes accompany memory formation and learning, and are induced by neurogenesis, neurodegeneration and brain injury such as stroke. Exploring the role of structural plasticity in the brain can be greatly assisted by mathematical and computational models, as they enable us to bridge the gap between system-level dynamics and lower level cellular and molecular processes. However, most traditional neural network models have fixed neuronal morphologies and a static connectivity pattern, with plasticity merely arising from changes in the strength of existing synapses (synaptic plasticity). In The Rewiring Brain, the editors bring together for the first time contemporary modeling studies that investigate the implications of structural plasticity for brain function and pathology. Starting with an experimental background on structural plasticity in the adult brain, the book covers computational studies on homeostatic structural plasticity, the impact of structural plasticity on cognition and cortical connectivity, the interaction between synaptic and structural plasticity, neurogenesis-related structural plasticity, and structural plasticity in neurological disorders. Structural plasticity adds a whole new dimension to brain plasticity, and The Rewiring Brain shows how computational approaches may help to gain a better understanding of the full adaptive potential of the adult brain. The book is written for both computational and experimental neuroscientists |
| Beschreibung: | Includes index Includes bibliographical references and index |
| Beschreibung: | 1 online resource |
| ISBN: | 9780128038727 0128038721 |
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| spelling | The rewiring brain a computational approach to structural plasticity in the adult brain edited by Arjen van Ooyen, VU University Amsterdam, Amsterdam, the Netherlands, Markus Butz-Ostendorf, Biomax Informatics AG, Planegg, Germany London Academic Press 2017 1 online resource txt rdacontent c rdamedia cr rdacarrier Includes index Includes bibliographical references and index The adult brain is not as hard-wired as traditionally thought. By modifying their small- or large-scale morphology, neurons can make new synaptic connections or break existing ones (structural plasticity). Structural changes accompany memory formation and learning, and are induced by neurogenesis, neurodegeneration and brain injury such as stroke. Exploring the role of structural plasticity in the brain can be greatly assisted by mathematical and computational models, as they enable us to bridge the gap between system-level dynamics and lower level cellular and molecular processes. However, most traditional neural network models have fixed neuronal morphologies and a static connectivity pattern, with plasticity merely arising from changes in the strength of existing synapses (synaptic plasticity). In The Rewiring Brain, the editors bring together for the first time contemporary modeling studies that investigate the implications of structural plasticity for brain function and pathology. Starting with an experimental background on structural plasticity in the adult brain, the book covers computational studies on homeostatic structural plasticity, the impact of structural plasticity on cognition and cortical connectivity, the interaction between synaptic and structural plasticity, neurogenesis-related structural plasticity, and structural plasticity in neurological disorders. Structural plasticity adds a whole new dimension to brain plasticity, and The Rewiring Brain shows how computational approaches may help to gain a better understanding of the full adaptive potential of the adult brain. The book is written for both computational and experimental neuroscientists MEDICAL / Physiology bisacsh SCIENCE / Life Sciences / Human Anatomy & Physiology bisacsh SCIENCE / Life Sciences / Neuroscience bisacsh Brain / Physiology fast Cognitive neuroscience fast Neuroplasticity fast Brain Physiology Cognitive neuroscience Neuroplasticity Plastizität (DE-588)4046283-3 gnd rswk-swf Gehirn (DE-588)4019752-9 gnd rswk-swf Gehirn (DE-588)4019752-9 s Plastizität (DE-588)4046283-3 s 1\p DE-604 Van Ooyen, Arjen edt Butz-Ostendorf, Markus edt Erscheint auch als Druck-Ausgabe 9780128037843 Erscheint auch als Druck-Ausgabe 0128037849 http://www.sciencedirect.com/science/book/9780128037843 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | The rewiring brain a computational approach to structural plasticity in the adult brain MEDICAL / Physiology bisacsh SCIENCE / Life Sciences / Human Anatomy & Physiology bisacsh SCIENCE / Life Sciences / Neuroscience bisacsh Brain / Physiology fast Cognitive neuroscience fast Neuroplasticity fast Brain Physiology Cognitive neuroscience Neuroplasticity Plastizität (DE-588)4046283-3 gnd Gehirn (DE-588)4019752-9 gnd |
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| title | The rewiring brain a computational approach to structural plasticity in the adult brain |
| title_auth | The rewiring brain a computational approach to structural plasticity in the adult brain |
| title_exact_search | The rewiring brain a computational approach to structural plasticity in the adult brain |
| title_full | The rewiring brain a computational approach to structural plasticity in the adult brain edited by Arjen van Ooyen, VU University Amsterdam, Amsterdam, the Netherlands, Markus Butz-Ostendorf, Biomax Informatics AG, Planegg, Germany |
| title_fullStr | The rewiring brain a computational approach to structural plasticity in the adult brain edited by Arjen van Ooyen, VU University Amsterdam, Amsterdam, the Netherlands, Markus Butz-Ostendorf, Biomax Informatics AG, Planegg, Germany |
| title_full_unstemmed | The rewiring brain a computational approach to structural plasticity in the adult brain edited by Arjen van Ooyen, VU University Amsterdam, Amsterdam, the Netherlands, Markus Butz-Ostendorf, Biomax Informatics AG, Planegg, Germany |
| title_short | The rewiring brain |
| title_sort | the rewiring brain a computational approach to structural plasticity in the adult brain |
| title_sub | a computational approach to structural plasticity in the adult brain |
| topic | MEDICAL / Physiology bisacsh SCIENCE / Life Sciences / Human Anatomy & Physiology bisacsh SCIENCE / Life Sciences / Neuroscience bisacsh Brain / Physiology fast Cognitive neuroscience fast Neuroplasticity fast Brain Physiology Cognitive neuroscience Neuroplasticity Plastizität (DE-588)4046283-3 gnd Gehirn (DE-588)4019752-9 gnd |
| topic_facet | MEDICAL / Physiology SCIENCE / Life Sciences / Human Anatomy & Physiology SCIENCE / Life Sciences / Neuroscience Brain / Physiology Cognitive neuroscience Neuroplasticity Brain Physiology Plastizität Gehirn |
| url | http://www.sciencedirect.com/science/book/9780128037843 |
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