Piperidine-based drug discovery:
Piperidine-Based Drug Discovery outlines the complexities of Piperidine scaffold use in drug discovery, including derivative chemistry, structural properties, methods of synthesis and practical implementations. Piperidine scaffolds are the cornerstones of over 70 commercialized drugs (including mult...
Gespeichert in:
1. Verfasser: | |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Amsterdam, Netherlands
Elsevier
[2017]
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Schriftenreihe: | Heterocyclic drug discovery series
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Schlagworte: | |
Online-Zugang: | FAW01 Volltext |
Zusammenfassung: | Piperidine-Based Drug Discovery outlines the complexities of Piperidine scaffold use in drug discovery, including derivative chemistry, structural properties, methods of synthesis and practical implementations. Piperidine scaffolds are the cornerstones of over 70 commercialized drugs (including multiple blockbusters). Designed as a guide for both experts and students working in this and related areas, it is hoped that this volume will encourage and inspire the continued design and development of novel pharmaceuticals based on Piperidine and its derivatives. Heterocyclic compounds are of central importance to medicinal chemistry, as demonstrated by the high percentage of marketable drugs that feature heterocyclic fragments in their structures. As starting points for drug discovery they offer a broad range of attractive properties, and a detailed understanding of the particular characteristics of each is of great benefit to researchers. The most commonly used heterocycle among US FDA approved pharmaceuticals, Piperidine is an extremely important building block in the synthesis of medicinal agents. This heterocycle and its derivatives exhibit a number of important functionalities and have been employed variously as CNS modulators, antiaggregants, anticoagulants, antihistamines, anti-cancer drugs and analgesics |
Beschreibung: | Includes bibliographical references and index |
Beschreibung: | 1 online resource illustrations |
ISBN: | 9780128134283 0128134283 |
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Datensatz im Suchindex
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any_adam_object | |
author | Vardanyan, R. S. |
author_facet | Vardanyan, R. S. |
author_role | aut |
author_sort | Vardanyan, R. S. |
author_variant | r s v rs rsv |
building | Verbundindex |
bvnumber | BV045382425 |
classification_rvk | VS 5350 |
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dewey-full | 615.19 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 615 - Pharmacology and therapeutics |
dewey-raw | 615.19 |
dewey-search | 615.19 |
dewey-sort | 3615.19 |
dewey-tens | 610 - Medicine and health |
discipline | Chemie / Pharmazie Medizin |
format | Electronic eBook |
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id | DE-604.BV045382425 |
illustrated | Illustrated |
indexdate | 2024-07-10T08:16:37Z |
institution | BVB |
isbn | 9780128134283 0128134283 |
language | English |
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physical | 1 online resource illustrations |
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publishDate | 2017 |
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publisher | Elsevier |
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series2 | Heterocyclic drug discovery series |
spelling | Vardanyan, R. S. Verfasser aut Piperidine-based drug discovery Ruben Vardanyan Amsterdam, Netherlands Elsevier [2017] 1 online resource illustrations txt rdacontent c rdamedia cr rdacarrier Heterocyclic drug discovery series Includes bibliographical references and index Piperidine-Based Drug Discovery outlines the complexities of Piperidine scaffold use in drug discovery, including derivative chemistry, structural properties, methods of synthesis and practical implementations. Piperidine scaffolds are the cornerstones of over 70 commercialized drugs (including multiple blockbusters). Designed as a guide for both experts and students working in this and related areas, it is hoped that this volume will encourage and inspire the continued design and development of novel pharmaceuticals based on Piperidine and its derivatives. Heterocyclic compounds are of central importance to medicinal chemistry, as demonstrated by the high percentage of marketable drugs that feature heterocyclic fragments in their structures. As starting points for drug discovery they offer a broad range of attractive properties, and a detailed understanding of the particular characteristics of each is of great benefit to researchers. The most commonly used heterocycle among US FDA approved pharmaceuticals, Piperidine is an extremely important building block in the synthesis of medicinal agents. This heterocycle and its derivatives exhibit a number of important functionalities and have been employed variously as CNS modulators, antiaggregants, anticoagulants, antihistamines, anti-cancer drugs and analgesics MEDICAL / Pharmacology bisacsh Drug development fast Drugs / Design fast Piperidine fast Drug Discovery Drugs Design Drug development Piperidine Erscheint auch als Druck-Ausgabe 9780128051573 Erscheint auch als Druck-Ausgabe 0128051574 http://www.sciencedirect.com/science/book/9780128051573 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Vardanyan, R. S. Piperidine-based drug discovery MEDICAL / Pharmacology bisacsh Drug development fast Drugs / Design fast Piperidine fast Drug Discovery Drugs Design Drug development Piperidine |
title | Piperidine-based drug discovery |
title_auth | Piperidine-based drug discovery |
title_exact_search | Piperidine-based drug discovery |
title_full | Piperidine-based drug discovery Ruben Vardanyan |
title_fullStr | Piperidine-based drug discovery Ruben Vardanyan |
title_full_unstemmed | Piperidine-based drug discovery Ruben Vardanyan |
title_short | Piperidine-based drug discovery |
title_sort | piperidine based drug discovery |
topic | MEDICAL / Pharmacology bisacsh Drug development fast Drugs / Design fast Piperidine fast Drug Discovery Drugs Design Drug development Piperidine |
topic_facet | MEDICAL / Pharmacology Drug development Drugs / Design Piperidine Drug Discovery Drugs Design |
url | http://www.sciencedirect.com/science/book/9780128051573 |
work_keys_str_mv | AT vardanyanrs piperidinebaseddrugdiscovery |