A roadmap for curing cancer, Alzheimer's, and cardiovascular disease:
Cancer, dementia, and cardiovascular disease are responsible for almost two million deaths each year in the United States alone and represent the largest immediate threat to humanity. Over the last century, we have made spectacular advances that have transformed our society - splitting the atom, spa...
Gespeichert in:
1. Verfasser: | |
---|---|
Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Amsterdam
Elsevier
[2017]
|
Schlagworte: | |
Online-Zugang: | FAW01 URL des Erstveröffentlichers |
Zusammenfassung: | Cancer, dementia, and cardiovascular disease are responsible for almost two million deaths each year in the United States alone and represent the largest immediate threat to humanity. Over the last century, we have made spectacular advances that have transformed our society - splitting the atom, space travel, telecommunications, and the Internet - but with medical research focused mostly on science for the sake of science, it has yielded precious few cures. A Roadmap for Curing Cancer, Alzheimer's, and Cardiovascular Disease represents a "first of its kind" effort to address both the reasons for this and to posit solutions to fix our broken system, in an effort to finally end this cure crisis. Dr. Marangos draws on 45 years of experience in every aspect of the biomedical R&D field, from basic drug discovery research at the NIH to the co-founding of five drug companies. He has published 252 research papers and edited four books on drug discovery, is co-inventor on 14 patents, and founded "The Journal of Molecular Neuroscience". He argues that from a development perspective, the regulatory, patent, and legal hurdles that force industry to pursue so-called "me-too" drugs rather than cures for terminal diseases must be re-thought. Leadership accountability, strategy, focus, and urgency need to be re-evaluated, and major reforms to the NIH, FDA, and patent codes are proposed.to remedy these impediments to cures. Written for anyone frustrated with the seemingly endless threat of terminal disease, this book seeks to inform, energize, and provide the rationale for the public and industry stakeholders, as well as clinicians and researchers, to resurrect the physician-patient relationship and demand that we get serious about ridding society of this scourge on humanity. This work contains the views and opinions of the author and are in no way intended to harm the reputation of any person, agency, organization, or commercial entity discussed herein |
Beschreibung: | Includes bibliographical references and index |
Beschreibung: | 1 online resource |
ISBN: | 9780128127971 012812797X |
Internformat
MARC
LEADER | 00000nmm a2200000zc 4500 | ||
---|---|---|---|
001 | BV045382333 | ||
003 | DE-604 | ||
005 | 00000000000000.0 | ||
007 | cr|uuu---uuuuu | ||
008 | 181228s2017 |||| o||u| ||||||eng d | ||
020 | |a 9780128127971 |9 978-0-12-812797-1 | ||
020 | |a 012812797X |9 0-12-812797-X | ||
035 | |a (ZDB-33-ESD)ocn985363710 | ||
035 | |a (ZDB-33-EBS)ocn985363710 | ||
035 | |a (OCoLC)985363710 | ||
035 | |a (DE-599)BVBBV045382333 | ||
040 | |a DE-604 |b ger |e rda | ||
041 | 0 | |a eng | |
049 | |a DE-1046 | ||
082 | 0 | |a 616.831 |2 23 | |
100 | 1 | |a Marangos, Paul J. |e Verfasser |4 aut | |
245 | 1 | 0 | |a A roadmap for curing cancer, Alzheimer's, and cardiovascular disease |c Paul J. Marangos |
264 | 1 | |a Amsterdam |b Elsevier |c [2017] | |
264 | 4 | |c © 2017 | |
300 | |a 1 online resource | ||
336 | |b txt |2 rdacontent | ||
337 | |b c |2 rdamedia | ||
338 | |b cr |2 rdacarrier | ||
500 | |a Includes bibliographical references and index | ||
520 | |a Cancer, dementia, and cardiovascular disease are responsible for almost two million deaths each year in the United States alone and represent the largest immediate threat to humanity. Over the last century, we have made spectacular advances that have transformed our society - splitting the atom, space travel, telecommunications, and the Internet - but with medical research focused mostly on science for the sake of science, it has yielded precious few cures. A Roadmap for Curing Cancer, Alzheimer's, and Cardiovascular Disease represents a "first of its kind" effort to address both the reasons for this and to posit solutions to fix our broken system, in an effort to finally end this cure crisis. Dr. Marangos draws on 45 years of experience in every aspect of the biomedical R&D field, from basic drug discovery research at the NIH to the co-founding of five drug companies. He has published 252 research papers and edited four books on drug discovery, is co-inventor on 14 patents, and founded "The Journal of Molecular Neuroscience". He argues that from a development perspective, the regulatory, patent, and legal hurdles that force industry to pursue so-called "me-too" drugs rather than cures for terminal diseases must be re-thought. Leadership accountability, strategy, focus, and urgency need to be re-evaluated, and major reforms to the NIH, FDA, and patent codes are proposed.to remedy these impediments to cures. Written for anyone frustrated with the seemingly endless threat of terminal disease, this book seeks to inform, energize, and provide the rationale for the public and industry stakeholders, as well as clinicians and researchers, to resurrect the physician-patient relationship and demand that we get serious about ridding society of this scourge on humanity. This work contains the views and opinions of the author and are in no way intended to harm the reputation of any person, agency, organization, or commercial entity discussed herein | ||
650 | 7 | |a HEALTH & FITNESS / Diseases / General |2 bisacsh | |
650 | 7 | |a MEDICAL / Clinical Medicine |2 bisacsh | |
650 | 7 | |a MEDICAL / Diseases |2 bisacsh | |
650 | 7 | |a MEDICAL / Evidence-Based Medicine |2 bisacsh | |
650 | 7 | |a MEDICAL / Internal Medicine |2 bisacsh | |
650 | 7 | |a Alzheimer's disease / Treatment |2 fast | |
650 | 7 | |a Cancer / Treatment |2 fast | |
650 | 7 | |a Cardiovascular system / Diseases / Treatment |2 fast | |
650 | 4 | |a Biomedical Research | |
650 | 4 | |a Cancer |x Treatment | |
650 | 4 | |a Alzheimer's disease |x Treatment | |
650 | 4 | |a Cardiovascular system |x Diseases |x Treatment | |
776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9780128127964 |
776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 0128127961 |
856 | 4 | 0 | |u http://www.sciencedirect.com/science/book/9780128127964 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
912 | |a ZDB-33-ESD |a ZDB-33-EBS | ||
999 | |a oai:aleph.bib-bvb.de:BVB01-030768666 | ||
966 | e | |u http://www.sciencedirect.com/science/book/9780128127964 |l FAW01 |p ZDB-33-ESD |q FAW_PDA_ESD |x Verlag |3 Volltext |
Datensatz im Suchindex
_version_ | 1804179234119221248 |
---|---|
any_adam_object | |
author | Marangos, Paul J. |
author_facet | Marangos, Paul J. |
author_role | aut |
author_sort | Marangos, Paul J. |
author_variant | p j m pj pjm |
building | Verbundindex |
bvnumber | BV045382333 |
collection | ZDB-33-ESD ZDB-33-EBS |
ctrlnum | (ZDB-33-ESD)ocn985363710 (ZDB-33-EBS)ocn985363710 (OCoLC)985363710 (DE-599)BVBBV045382333 |
dewey-full | 616.831 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 616 - Diseases |
dewey-raw | 616.831 |
dewey-search | 616.831 |
dewey-sort | 3616.831 |
dewey-tens | 610 - Medicine and health |
discipline | Medizin |
format | Electronic eBook |
fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03999nmm a2200541zc 4500</leader><controlfield tag="001">BV045382333</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">181228s2017 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9780128127971</subfield><subfield code="9">978-0-12-812797-1</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">012812797X</subfield><subfield code="9">0-12-812797-X</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-33-ESD)ocn985363710</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-33-EBS)ocn985363710</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)985363710</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV045382333</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-1046</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">616.831</subfield><subfield code="2">23</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Marangos, Paul J.</subfield><subfield code="e">Verfasser</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">A roadmap for curing cancer, Alzheimer's, and cardiovascular disease</subfield><subfield code="c">Paul J. Marangos</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Amsterdam</subfield><subfield code="b">Elsevier</subfield><subfield code="c">[2017]</subfield></datafield><datafield tag="264" ind1=" " ind2="4"><subfield code="c">© 2017</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 online resource</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Includes bibliographical references and index</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Cancer, dementia, and cardiovascular disease are responsible for almost two million deaths each year in the United States alone and represent the largest immediate threat to humanity. Over the last century, we have made spectacular advances that have transformed our society - splitting the atom, space travel, telecommunications, and the Internet - but with medical research focused mostly on science for the sake of science, it has yielded precious few cures. A Roadmap for Curing Cancer, Alzheimer's, and Cardiovascular Disease represents a "first of its kind" effort to address both the reasons for this and to posit solutions to fix our broken system, in an effort to finally end this cure crisis. Dr. Marangos draws on 45 years of experience in every aspect of the biomedical R&D field, from basic drug discovery research at the NIH to the co-founding of five drug companies. He has published 252 research papers and edited four books on drug discovery, is co-inventor on 14 patents, and founded "The Journal of Molecular Neuroscience". He argues that from a development perspective, the regulatory, patent, and legal hurdles that force industry to pursue so-called "me-too" drugs rather than cures for terminal diseases must be re-thought. Leadership accountability, strategy, focus, and urgency need to be re-evaluated, and major reforms to the NIH, FDA, and patent codes are proposed.to remedy these impediments to cures. Written for anyone frustrated with the seemingly endless threat of terminal disease, this book seeks to inform, energize, and provide the rationale for the public and industry stakeholders, as well as clinicians and researchers, to resurrect the physician-patient relationship and demand that we get serious about ridding society of this scourge on humanity. This work contains the views and opinions of the author and are in no way intended to harm the reputation of any person, agency, organization, or commercial entity discussed herein</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">HEALTH & FITNESS / Diseases / General</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">MEDICAL / Clinical Medicine</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">MEDICAL / Diseases</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">MEDICAL / Evidence-Based Medicine</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">MEDICAL / Internal Medicine</subfield><subfield code="2">bisacsh</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Alzheimer's disease / Treatment</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Cancer / Treatment</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Cardiovascular system / Diseases / Treatment</subfield><subfield code="2">fast</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Biomedical Research</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cancer</subfield><subfield code="x">Treatment</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Alzheimer's disease</subfield><subfield code="x">Treatment</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cardiovascular system</subfield><subfield code="x">Diseases</subfield><subfield code="x">Treatment</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9780128127964</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">0128127961</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://www.sciencedirect.com/science/book/9780128127964</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-33-ESD</subfield><subfield code="a">ZDB-33-EBS</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-030768666</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">http://www.sciencedirect.com/science/book/9780128127964</subfield><subfield code="l">FAW01</subfield><subfield code="p">ZDB-33-ESD</subfield><subfield code="q">FAW_PDA_ESD</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
id | DE-604.BV045382333 |
illustrated | Not Illustrated |
indexdate | 2024-07-10T08:16:37Z |
institution | BVB |
isbn | 9780128127971 012812797X |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-030768666 |
oclc_num | 985363710 |
open_access_boolean | |
owner | DE-1046 |
owner_facet | DE-1046 |
physical | 1 online resource |
psigel | ZDB-33-ESD ZDB-33-EBS ZDB-33-ESD FAW_PDA_ESD |
publishDate | 2017 |
publishDateSearch | 2017 |
publishDateSort | 2017 |
publisher | Elsevier |
record_format | marc |
spelling | Marangos, Paul J. Verfasser aut A roadmap for curing cancer, Alzheimer's, and cardiovascular disease Paul J. Marangos Amsterdam Elsevier [2017] © 2017 1 online resource txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references and index Cancer, dementia, and cardiovascular disease are responsible for almost two million deaths each year in the United States alone and represent the largest immediate threat to humanity. Over the last century, we have made spectacular advances that have transformed our society - splitting the atom, space travel, telecommunications, and the Internet - but with medical research focused mostly on science for the sake of science, it has yielded precious few cures. A Roadmap for Curing Cancer, Alzheimer's, and Cardiovascular Disease represents a "first of its kind" effort to address both the reasons for this and to posit solutions to fix our broken system, in an effort to finally end this cure crisis. Dr. Marangos draws on 45 years of experience in every aspect of the biomedical R&D field, from basic drug discovery research at the NIH to the co-founding of five drug companies. He has published 252 research papers and edited four books on drug discovery, is co-inventor on 14 patents, and founded "The Journal of Molecular Neuroscience". He argues that from a development perspective, the regulatory, patent, and legal hurdles that force industry to pursue so-called "me-too" drugs rather than cures for terminal diseases must be re-thought. Leadership accountability, strategy, focus, and urgency need to be re-evaluated, and major reforms to the NIH, FDA, and patent codes are proposed.to remedy these impediments to cures. Written for anyone frustrated with the seemingly endless threat of terminal disease, this book seeks to inform, energize, and provide the rationale for the public and industry stakeholders, as well as clinicians and researchers, to resurrect the physician-patient relationship and demand that we get serious about ridding society of this scourge on humanity. This work contains the views and opinions of the author and are in no way intended to harm the reputation of any person, agency, organization, or commercial entity discussed herein HEALTH & FITNESS / Diseases / General bisacsh MEDICAL / Clinical Medicine bisacsh MEDICAL / Diseases bisacsh MEDICAL / Evidence-Based Medicine bisacsh MEDICAL / Internal Medicine bisacsh Alzheimer's disease / Treatment fast Cancer / Treatment fast Cardiovascular system / Diseases / Treatment fast Biomedical Research Cancer Treatment Alzheimer's disease Treatment Cardiovascular system Diseases Treatment Erscheint auch als Druck-Ausgabe 9780128127964 Erscheint auch als Druck-Ausgabe 0128127961 http://www.sciencedirect.com/science/book/9780128127964 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Marangos, Paul J. A roadmap for curing cancer, Alzheimer's, and cardiovascular disease HEALTH & FITNESS / Diseases / General bisacsh MEDICAL / Clinical Medicine bisacsh MEDICAL / Diseases bisacsh MEDICAL / Evidence-Based Medicine bisacsh MEDICAL / Internal Medicine bisacsh Alzheimer's disease / Treatment fast Cancer / Treatment fast Cardiovascular system / Diseases / Treatment fast Biomedical Research Cancer Treatment Alzheimer's disease Treatment Cardiovascular system Diseases Treatment |
title | A roadmap for curing cancer, Alzheimer's, and cardiovascular disease |
title_auth | A roadmap for curing cancer, Alzheimer's, and cardiovascular disease |
title_exact_search | A roadmap for curing cancer, Alzheimer's, and cardiovascular disease |
title_full | A roadmap for curing cancer, Alzheimer's, and cardiovascular disease Paul J. Marangos |
title_fullStr | A roadmap for curing cancer, Alzheimer's, and cardiovascular disease Paul J. Marangos |
title_full_unstemmed | A roadmap for curing cancer, Alzheimer's, and cardiovascular disease Paul J. Marangos |
title_short | A roadmap for curing cancer, Alzheimer's, and cardiovascular disease |
title_sort | a roadmap for curing cancer alzheimer s and cardiovascular disease |
topic | HEALTH & FITNESS / Diseases / General bisacsh MEDICAL / Clinical Medicine bisacsh MEDICAL / Diseases bisacsh MEDICAL / Evidence-Based Medicine bisacsh MEDICAL / Internal Medicine bisacsh Alzheimer's disease / Treatment fast Cancer / Treatment fast Cardiovascular system / Diseases / Treatment fast Biomedical Research Cancer Treatment Alzheimer's disease Treatment Cardiovascular system Diseases Treatment |
topic_facet | HEALTH & FITNESS / Diseases / General MEDICAL / Clinical Medicine MEDICAL / Diseases MEDICAL / Evidence-Based Medicine MEDICAL / Internal Medicine Alzheimer's disease / Treatment Cancer / Treatment Cardiovascular system / Diseases / Treatment Biomedical Research Cancer Treatment Alzheimer's disease Treatment Cardiovascular system Diseases Treatment |
url | http://www.sciencedirect.com/science/book/9780128127964 |
work_keys_str_mv | AT marangospaulj aroadmapforcuringcanceralzheimersandcardiovasculardisease |