Validamycin and its derivatives: discovery, chemical synthesis, and biological activity
Validamycin and its derivatives: discovery, chemical synthesis and biological activity presents, for the first time, a complete review of the underlying chemistry, synthesis, behavior and application of these compounds. Beginning with an introduction to validamycin, the book then outlines the key el...
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Hauptverfasser: | , , , |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Amsterdam, Netherlands
Elsevier
2017
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Schlagworte: | |
Online-Zugang: | FAW01 URL des Erstveröffentlichers |
Zusammenfassung: | Validamycin and its derivatives: discovery, chemical synthesis and biological activity presents, for the first time, a complete review of the underlying chemistry, synthesis, behavior and application of these compounds. Beginning with an introduction to validamycin, the book then outlines the key elements of its discovery and production, including details of its structures, isolation, analysis, and issues relating to its large scale production. Biological activities are then explored in more detail, followed by details of biosynthesis. Further to this, the chemical synthesis of validamycin and its intermediates, including valienamine, validamine, valiolamine, and validoxylamines is reviewed, before preparation of these derivatives and their biological activities are explored. Finally, the book concludes with a discussion of the economic aspects of working with validamycin and its potential in future applications and trends. With its detailed chemical coverage from a team of expert authors, this detailed guide can be applied to the large-scale industrial production of antibiotics and the adaptation of bioactive agents, from agricultural, to novel pharmaceutical applications. Offers complete coverage of validamycin chemistry from a highly experienced team of authors |
Beschreibung: | Includes bibliographical references and index |
Beschreibung: | 1 online resource |
ISBN: | 9780081011133 008101113X |
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520 | |a Validamycin and its derivatives: discovery, chemical synthesis and biological activity presents, for the first time, a complete review of the underlying chemistry, synthesis, behavior and application of these compounds. Beginning with an introduction to validamycin, the book then outlines the key elements of its discovery and production, including details of its structures, isolation, analysis, and issues relating to its large scale production. Biological activities are then explored in more detail, followed by details of biosynthesis. Further to this, the chemical synthesis of validamycin and its intermediates, including valienamine, validamine, valiolamine, and validoxylamines is reviewed, before preparation of these derivatives and their biological activities are explored. Finally, the book concludes with a discussion of the economic aspects of working with validamycin and its potential in future applications and trends. With its detailed chemical coverage from a team of expert authors, this detailed guide can be applied to the large-scale industrial production of antibiotics and the adaptation of bioactive agents, from agricultural, to novel pharmaceutical applications. Offers complete coverage of validamycin chemistry from a highly experienced team of authors | ||
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Datensatz im Suchindex
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any_adam_object | |
author | Chen, Xiaolong Lu, Yuele Fan, Yongxian Shen, Yinchu |
author_facet | Chen, Xiaolong Lu, Yuele Fan, Yongxian Shen, Yinchu |
author_role | aut aut aut aut |
author_sort | Chen, Xiaolong |
author_variant | x c xc y l yl y f yf y s ys |
building | Verbundindex |
bvnumber | BV045382310 |
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ctrlnum | (ZDB-33-ESD)ocn981463362 (ZDB-33-EBS)ocn981463362 (OCoLC)981463362 (DE-599)BVBBV045382310 |
dewey-full | 615.3/29 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 615 - Pharmacology and therapeutics |
dewey-raw | 615.3/29 |
dewey-search | 615.3/29 |
dewey-sort | 3615.3 229 |
dewey-tens | 610 - Medicine and health |
discipline | Medizin |
format | Electronic eBook |
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id | DE-604.BV045382310 |
illustrated | Not Illustrated |
indexdate | 2024-07-10T08:16:37Z |
institution | BVB |
isbn | 9780081011133 008101113X |
language | English |
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spelling | Chen, Xiaolong Verfasser aut Validamycin and its derivatives discovery, chemical synthesis, and biological activity Xiaolong Chen, Yuele Lu, Yongxian Fan and Yinchu Shen, Institute of Fermentation Engineering, Zhejiang University of Technology, Hangzhou, PR China Amsterdam, Netherlands Elsevier 2017 1 online resource txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references and index Validamycin and its derivatives: discovery, chemical synthesis and biological activity presents, for the first time, a complete review of the underlying chemistry, synthesis, behavior and application of these compounds. Beginning with an introduction to validamycin, the book then outlines the key elements of its discovery and production, including details of its structures, isolation, analysis, and issues relating to its large scale production. Biological activities are then explored in more detail, followed by details of biosynthesis. Further to this, the chemical synthesis of validamycin and its intermediates, including valienamine, validamine, valiolamine, and validoxylamines is reviewed, before preparation of these derivatives and their biological activities are explored. Finally, the book concludes with a discussion of the economic aspects of working with validamycin and its potential in future applications and trends. With its detailed chemical coverage from a team of expert authors, this detailed guide can be applied to the large-scale industrial production of antibiotics and the adaptation of bioactive agents, from agricultural, to novel pharmaceutical applications. Offers complete coverage of validamycin chemistry from a highly experienced team of authors MEDICAL / Pharmacology bisacsh Antibiotics fast Biosynthesis fast Fungicides fast Antibiotics Fungicides Biosynthesis Lu, Yuele aut Fan, Yongxian aut Shen, Yinchu aut Erscheint auch als Druck-Ausgabe 9780081009994 Erscheint auch als Druck-Ausgabe 0081009992 http://www.sciencedirect.com/science/book/9780081009994 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Chen, Xiaolong Lu, Yuele Fan, Yongxian Shen, Yinchu Validamycin and its derivatives discovery, chemical synthesis, and biological activity MEDICAL / Pharmacology bisacsh Antibiotics fast Biosynthesis fast Fungicides fast Antibiotics Fungicides Biosynthesis |
title | Validamycin and its derivatives discovery, chemical synthesis, and biological activity |
title_auth | Validamycin and its derivatives discovery, chemical synthesis, and biological activity |
title_exact_search | Validamycin and its derivatives discovery, chemical synthesis, and biological activity |
title_full | Validamycin and its derivatives discovery, chemical synthesis, and biological activity Xiaolong Chen, Yuele Lu, Yongxian Fan and Yinchu Shen, Institute of Fermentation Engineering, Zhejiang University of Technology, Hangzhou, PR China |
title_fullStr | Validamycin and its derivatives discovery, chemical synthesis, and biological activity Xiaolong Chen, Yuele Lu, Yongxian Fan and Yinchu Shen, Institute of Fermentation Engineering, Zhejiang University of Technology, Hangzhou, PR China |
title_full_unstemmed | Validamycin and its derivatives discovery, chemical synthesis, and biological activity Xiaolong Chen, Yuele Lu, Yongxian Fan and Yinchu Shen, Institute of Fermentation Engineering, Zhejiang University of Technology, Hangzhou, PR China |
title_short | Validamycin and its derivatives |
title_sort | validamycin and its derivatives discovery chemical synthesis and biological activity |
title_sub | discovery, chemical synthesis, and biological activity |
topic | MEDICAL / Pharmacology bisacsh Antibiotics fast Biosynthesis fast Fungicides fast Antibiotics Fungicides Biosynthesis |
topic_facet | MEDICAL / Pharmacology Antibiotics Biosynthesis Fungicides |
url | http://www.sciencedirect.com/science/book/9780081009994 |
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