Translational neuroimmunology in multiple sclerosis: from disease mechanisms to clinical applications
Multiple sclerosis (MS) is the most common disabling neurological disease of young adults. More than 2.3 million people are affected by MS worldwide. Symptoms can vary widely, depending on the localization and amount of the damage induced by combined inflammatory, demyelinating, and neurodegenerativ...
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| Format: | Elektronisch E-Book |
| Sprache: | English |
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Amsterdam
Academic Press is an imprint Elsevier
[2016]
|
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| Online-Zugang: | URL des Erstveröffentlichers |
| Zusammenfassung: | Multiple sclerosis (MS) is the most common disabling neurological disease of young adults. More than 2.3 million people are affected by MS worldwide. Symptoms can vary widely, depending on the localization and amount of the damage induced by combined inflammatory, demyelinating, and neurodegenerative processes. Although a cure for MS does not currently exist, therapies can help treat MS attacks, attenuate disease activity, reduce progress of the disease, and manage symptoms. Translational Neuroimmunology in Multiple Sclerosis provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis, from experimental models and the human disease to the translation of this research to immunotherapeutic strategies. Chapters describe genetic and environmental factors underlying the disease pathogenesis of MS as a basis for development of immunotherapies, immunological markers of disease activity, pharmacogenetics, and responses to therapy. Immunomodulatory therapies currently in practice and future therapeutic strategies on the horizon-such as neuroprotective strategies, stem cells, and repair promotion-are discussed. Contributed by renowned leaders in the field, this cross-disciplinary volume is a great resource for basic scientists and clinical practitioners in neuroscience, neurology, immunology, pharmacology, and in-drug development |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | 1 online resource color illustrations |
| ISBN: | 9780128020074 0128020075 |
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| 520 | |a Multiple sclerosis (MS) is the most common disabling neurological disease of young adults. More than 2.3 million people are affected by MS worldwide. Symptoms can vary widely, depending on the localization and amount of the damage induced by combined inflammatory, demyelinating, and neurodegenerative processes. Although a cure for MS does not currently exist, therapies can help treat MS attacks, attenuate disease activity, reduce progress of the disease, and manage symptoms. Translational Neuroimmunology in Multiple Sclerosis provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis, from experimental models and the human disease to the translation of this research to immunotherapeutic strategies. Chapters describe genetic and environmental factors underlying the disease pathogenesis of MS as a basis for development of immunotherapies, immunological markers of disease activity, pharmacogenetics, and responses to therapy. Immunomodulatory therapies currently in practice and future therapeutic strategies on the horizon-such as neuroprotective strategies, stem cells, and repair promotion-are discussed. Contributed by renowned leaders in the field, this cross-disciplinary volume is a great resource for basic scientists and clinical practitioners in neuroscience, neurology, immunology, pharmacology, and in-drug development | ||
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| spelling | Translational neuroimmunology in multiple sclerosis from disease mechanisms to clinical applications edited by Ruth Arnon, Ariel Miller Amsterdam Academic Press is an imprint Elsevier [2016] © 2016 1 online resource color illustrations txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references and index Multiple sclerosis (MS) is the most common disabling neurological disease of young adults. More than 2.3 million people are affected by MS worldwide. Symptoms can vary widely, depending on the localization and amount of the damage induced by combined inflammatory, demyelinating, and neurodegenerative processes. Although a cure for MS does not currently exist, therapies can help treat MS attacks, attenuate disease activity, reduce progress of the disease, and manage symptoms. Translational Neuroimmunology in Multiple Sclerosis provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis, from experimental models and the human disease to the translation of this research to immunotherapeutic strategies. Chapters describe genetic and environmental factors underlying the disease pathogenesis of MS as a basis for development of immunotherapies, immunological markers of disease activity, pharmacogenetics, and responses to therapy. Immunomodulatory therapies currently in practice and future therapeutic strategies on the horizon-such as neuroprotective strategies, stem cells, and repair promotion-are discussed. Contributed by renowned leaders in the field, this cross-disciplinary volume is a great resource for basic scientists and clinical practitioners in neuroscience, neurology, immunology, pharmacology, and in-drug development HEALTH & FITNESS / Diseases / General bisacsh MEDICAL / Clinical Medicine bisacsh MEDICAL / Diseases bisacsh MEDICAL / Evidence-Based Medicine bisacsh MEDICAL / Internal Medicine bisacsh Multiple sclerosis fast Neuroimmunology fast Multiple sclerosis Neuroimmunology Arnon, R. edt Miller, Ariel edt Erscheint auch als Druck-Ausgabe 9780128019146 Erscheint auch als Druck-Ausgabe 012801914X http://www.sciencedirect.com/science/book/9780128019146 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Translational neuroimmunology in multiple sclerosis from disease mechanisms to clinical applications HEALTH & FITNESS / Diseases / General bisacsh MEDICAL / Clinical Medicine bisacsh MEDICAL / Diseases bisacsh MEDICAL / Evidence-Based Medicine bisacsh MEDICAL / Internal Medicine bisacsh Multiple sclerosis fast Neuroimmunology fast Multiple sclerosis Neuroimmunology |
| title | Translational neuroimmunology in multiple sclerosis from disease mechanisms to clinical applications |
| title_auth | Translational neuroimmunology in multiple sclerosis from disease mechanisms to clinical applications |
| title_exact_search | Translational neuroimmunology in multiple sclerosis from disease mechanisms to clinical applications |
| title_full | Translational neuroimmunology in multiple sclerosis from disease mechanisms to clinical applications edited by Ruth Arnon, Ariel Miller |
| title_fullStr | Translational neuroimmunology in multiple sclerosis from disease mechanisms to clinical applications edited by Ruth Arnon, Ariel Miller |
| title_full_unstemmed | Translational neuroimmunology in multiple sclerosis from disease mechanisms to clinical applications edited by Ruth Arnon, Ariel Miller |
| title_short | Translational neuroimmunology in multiple sclerosis |
| title_sort | translational neuroimmunology in multiple sclerosis from disease mechanisms to clinical applications |
| title_sub | from disease mechanisms to clinical applications |
| topic | HEALTH & FITNESS / Diseases / General bisacsh MEDICAL / Clinical Medicine bisacsh MEDICAL / Diseases bisacsh MEDICAL / Evidence-Based Medicine bisacsh MEDICAL / Internal Medicine bisacsh Multiple sclerosis fast Neuroimmunology fast Multiple sclerosis Neuroimmunology |
| topic_facet | HEALTH & FITNESS / Diseases / General MEDICAL / Clinical Medicine MEDICAL / Diseases MEDICAL / Evidence-Based Medicine MEDICAL / Internal Medicine Multiple sclerosis Neuroimmunology |
| url | http://www.sciencedirect.com/science/book/9780128019146 |
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