Atlas of histology of the juvenile rat:
Atlas of Histology of the Juvenile Rat should be of interest to toxicologic pathologists, toxicologists, and other biological scientists who are interested in the histomorphology of juvenile rats. For several decades the laboratory rat has been used extensively in nonclinical toxicology studies desi...
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| Weitere Verfasser: | , |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
London, UK
Academic Press is an imprint of Elsevier
[2016]
|
| Schlagworte: | |
| Online-Zugang: | URL des Erstveröffentlichers |
| Zusammenfassung: | Atlas of Histology of the Juvenile Rat should be of interest to toxicologic pathologists, toxicologists, and other biological scientists who are interested in the histomorphology of juvenile rats. For several decades the laboratory rat has been used extensively in nonclinical toxicology studies designed to detect potential human toxicity of drugs, agrochemicals, industrial chemicals, and environmental hazards. These studies traditionally have involved young adult rats that are 8-10 weeks of age as studies are started. It is becoming increasingly apparent that children and young animals may have different responses to drug/chemical exposures, therefore, regulatory agencies are emphasizing toxicology studies in juvenile animals. While the histologic features of organs from young adult and aged laboratory rats are well known, less is known about the histologic features of organs from juvenile rats. Final histologic maturity of many organs is achieved postnatally, thus immature histologic features must be distinguished from chemical- or drug-related effects. While this postnatal organ development is known to exist as a general concept, detailed information regarding postnatal histologic development is not readily available. The Atlas includes organs that are typically sampled in nonclinical toxicology studies and presents the histologic features at weekly intervals, starting at birth and extending through postnatal day 42 |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | 1 online resource (xiii, 448 pages) illustrations |
| ISBN: | 9780128026960 0128026960 |
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| 520 | |a Atlas of Histology of the Juvenile Rat should be of interest to toxicologic pathologists, toxicologists, and other biological scientists who are interested in the histomorphology of juvenile rats. For several decades the laboratory rat has been used extensively in nonclinical toxicology studies designed to detect potential human toxicity of drugs, agrochemicals, industrial chemicals, and environmental hazards. These studies traditionally have involved young adult rats that are 8-10 weeks of age as studies are started. It is becoming increasingly apparent that children and young animals may have different responses to drug/chemical exposures, therefore, regulatory agencies are emphasizing toxicology studies in juvenile animals. While the histologic features of organs from young adult and aged laboratory rats are well known, less is known about the histologic features of organs from juvenile rats. Final histologic maturity of many organs is achieved postnatally, thus immature histologic features must be distinguished from chemical- or drug-related effects. While this postnatal organ development is known to exist as a general concept, detailed information regarding postnatal histologic development is not readily available. The Atlas includes organs that are typically sampled in nonclinical toxicology studies and presents the histologic features at weekly intervals, starting at birth and extending through postnatal day 42 | ||
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Datensatz im Suchindex
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| dewey-full | 636.02/733 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 636 - Animal husbandry |
| dewey-raw | 636.02/733 |
| dewey-search | 636.02/733 |
| dewey-sort | 3636.02 3733 |
| dewey-tens | 630 - Agriculture and related technologies |
| discipline | Biologie Agrar-/Forst-/Ernährungs-/Haushaltswissenschaft / Gartenbau |
| format | Electronic eBook |
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| spelling | Atlas of histology of the juvenile rat edited by George A. Parker and Catherine A. Picut London, UK Academic Press is an imprint of Elsevier [2016] © 2016 1 online resource (xiii, 448 pages) illustrations txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references and index Atlas of Histology of the Juvenile Rat should be of interest to toxicologic pathologists, toxicologists, and other biological scientists who are interested in the histomorphology of juvenile rats. For several decades the laboratory rat has been used extensively in nonclinical toxicology studies designed to detect potential human toxicity of drugs, agrochemicals, industrial chemicals, and environmental hazards. These studies traditionally have involved young adult rats that are 8-10 weeks of age as studies are started. It is becoming increasingly apparent that children and young animals may have different responses to drug/chemical exposures, therefore, regulatory agencies are emphasizing toxicology studies in juvenile animals. While the histologic features of organs from young adult and aged laboratory rats are well known, less is known about the histologic features of organs from juvenile rats. Final histologic maturity of many organs is achieved postnatally, thus immature histologic features must be distinguished from chemical- or drug-related effects. While this postnatal organ development is known to exist as a general concept, detailed information regarding postnatal histologic development is not readily available. The Atlas includes organs that are typically sampled in nonclinical toxicology studies and presents the histologic features at weekly intervals, starting at birth and extending through postnatal day 42 NATURE / Animals / Mammals bisacsh SCIENCE / Life Sciences / Zoology / Mammals bisacsh Rats as laboratory animals fast Rats Histology Atlases Rats as laboratory animals Atlases Histologie (DE-588)4025092-1 gnd rswk-swf Ratte (DE-588)4177011-0 gnd rswk-swf 1\p (DE-588)4143303-8 Atlas gnd-content Ratte (DE-588)4177011-0 s Histologie (DE-588)4025092-1 s 2\p DE-604 Parker, George A. edt Picut, Catherine A. edt Erscheint auch als Druck-Ausgabe 9780128026823 Erscheint auch als Druck-Ausgabe 0128026820 http://www.sciencedirect.com/science/book/9780128026823 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Atlas of histology of the juvenile rat NATURE / Animals / Mammals bisacsh SCIENCE / Life Sciences / Zoology / Mammals bisacsh Rats as laboratory animals fast Rats Histology Atlases Rats as laboratory animals Atlases Histologie (DE-588)4025092-1 gnd Ratte (DE-588)4177011-0 gnd |
| subject_GND | (DE-588)4025092-1 (DE-588)4177011-0 (DE-588)4143303-8 |
| title | Atlas of histology of the juvenile rat |
| title_auth | Atlas of histology of the juvenile rat |
| title_exact_search | Atlas of histology of the juvenile rat |
| title_full | Atlas of histology of the juvenile rat edited by George A. Parker and Catherine A. Picut |
| title_fullStr | Atlas of histology of the juvenile rat edited by George A. Parker and Catherine A. Picut |
| title_full_unstemmed | Atlas of histology of the juvenile rat edited by George A. Parker and Catherine A. Picut |
| title_short | Atlas of histology of the juvenile rat |
| title_sort | atlas of histology of the juvenile rat |
| topic | NATURE / Animals / Mammals bisacsh SCIENCE / Life Sciences / Zoology / Mammals bisacsh Rats as laboratory animals fast Rats Histology Atlases Rats as laboratory animals Atlases Histologie (DE-588)4025092-1 gnd Ratte (DE-588)4177011-0 gnd |
| topic_facet | NATURE / Animals / Mammals SCIENCE / Life Sciences / Zoology / Mammals Rats as laboratory animals Rats Histology Atlases Rats as laboratory animals Atlases Histologie Ratte Atlas |
| url | http://www.sciencedirect.com/science/book/9780128026823 |
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