The comprehensive sourcebook of bacterial protein toxins:
Bacterial toxins play an important role in infectious diseases. Several are amongst the most potent biological agents known to man. Cholera, pertussis, botulinum, clostridium and tetanus toxins are all produced by bacteria. In many cases, it is the toxin produced and not the infectious agent itself...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Amsterdam
Elsevier
[2015]
|
| Ausgabe: | 4. ed. |
| Schlagworte: | |
| Online-Zugang: | FUBA1 URL des Erstveröffentlichers |
| Zusammenfassung: | Bacterial toxins play an important role in infectious diseases. Several are amongst the most potent biological agents known to man. Cholera, pertussis, botulinum, clostridium and tetanus toxins are all produced by bacteria. In many cases, it is the toxin produced and not the infectious agent itself that causes pathology. Botulinum toxin has now of course found clinical application as botox, and anthrax, and other toxins, have potentially devastating effects if misused as an agent of biological terror. This book describes the major achievements and discoveries relevant to bacterial protein toxins since the turn of the new century, illustrated by the discovery of more than fifty novel toxins (many of them identified through genome screening). The establishment of the three-dimensional crystal structure of more than 20 toxins during the same period offers deeper knowledge of structure-activity relationships and provides a framework to understand how toxins recognize receptors, penetrate membranes and interact with and modify intracellular substrates |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | 1 online resource (XVIII, 1182 S.) Ill. |
| ISBN: | 9780128005897 0128005890 |
Internformat
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| 245 | 1 | 0 | |a The comprehensive sourcebook of bacterial protein toxins |c [edited by] Joseph E. Alouf, Institut Pasteur, Paris, France, Daniel Ladant, Institut Pasteur, Unité de Biochimie des Interactions Moléculaires, Paris France [and] Michel R. Popoff, Instit Pasteur, Unité des Bactéries anaérobies et Toxines, Paris, France |
| 246 | 1 | 3 | |a Bacterial protein toxins |
| 250 | |a 4. ed. | ||
| 264 | 1 | |a Amsterdam |b Elsevier |c [2015] | |
| 264 | 4 | |c © 2015 | |
| 300 | |a 1 online resource (XVIII, 1182 S.) |b Ill. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 500 | |a Includes bibliographical references and index | ||
| 520 | |a Bacterial toxins play an important role in infectious diseases. Several are amongst the most potent biological agents known to man. Cholera, pertussis, botulinum, clostridium and tetanus toxins are all produced by bacteria. In many cases, it is the toxin produced and not the infectious agent itself that causes pathology. Botulinum toxin has now of course found clinical application as botox, and anthrax, and other toxins, have potentially devastating effects if misused as an agent of biological terror. This book describes the major achievements and discoveries relevant to bacterial protein toxins since the turn of the new century, illustrated by the discovery of more than fifty novel toxins (many of them identified through genome screening). The establishment of the three-dimensional crystal structure of more than 20 toxins during the same period offers deeper knowledge of structure-activity relationships and provides a framework to understand how toxins recognize receptors, penetrate membranes and interact with and modify intracellular substrates | ||
| 650 | 4 | |a Bacterial Toxins | |
| 650 | 4 | |a Bacterial Proteins | |
| 650 | 4 | |a Toxines bactériennes | |
| 650 | 7 | |a MEDICAL / Pharmacology |2 bisacsh | |
| 650 | 7 | |a Bacterial toxins |2 fast | |
| 650 | 4 | |a Bacterial toxins | |
| 650 | 0 | 7 | |a Proteintoxin |0 (DE-588)4811458-3 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Bakteriengift |0 (DE-588)4130547-4 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Bakteriengift |0 (DE-588)4130547-4 |D s |
| 689 | 0 | 1 | |a Proteintoxin |0 (DE-588)4811458-3 |D s |
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| 700 | 1 | |a Alouf, Joseph E. |4 edt | |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 978-0-12-800188-2 |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 0128001887 |
| 856 | 4 | 0 | |u http://www.sciencedirect.com/science/book/9780128001882 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
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Datensatz im Suchindex
| _version_ | 1804179232677429248 |
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| author2 | Alouf, Joseph E. |
| author2_role | edt |
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| author_facet | Alouf, Joseph E. |
| building | Verbundindex |
| bvnumber | BV045381656 |
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| dewey-full | 615.9/5293 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615.9/5293 |
| dewey-search | 615.9/5293 |
| dewey-sort | 3615.9 45293 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| edition | 4. ed. |
| format | Electronic eBook |
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| isbn | 9780128005897 0128005890 |
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| spelling | The comprehensive sourcebook of bacterial protein toxins [edited by] Joseph E. Alouf, Institut Pasteur, Paris, France, Daniel Ladant, Institut Pasteur, Unité de Biochimie des Interactions Moléculaires, Paris France [and] Michel R. Popoff, Instit Pasteur, Unité des Bactéries anaérobies et Toxines, Paris, France Bacterial protein toxins 4. ed. Amsterdam Elsevier [2015] © 2015 1 online resource (XVIII, 1182 S.) Ill. txt rdacontent c rdamedia cr rdacarrier Includes bibliographical references and index Bacterial toxins play an important role in infectious diseases. Several are amongst the most potent biological agents known to man. Cholera, pertussis, botulinum, clostridium and tetanus toxins are all produced by bacteria. In many cases, it is the toxin produced and not the infectious agent itself that causes pathology. Botulinum toxin has now of course found clinical application as botox, and anthrax, and other toxins, have potentially devastating effects if misused as an agent of biological terror. This book describes the major achievements and discoveries relevant to bacterial protein toxins since the turn of the new century, illustrated by the discovery of more than fifty novel toxins (many of them identified through genome screening). The establishment of the three-dimensional crystal structure of more than 20 toxins during the same period offers deeper knowledge of structure-activity relationships and provides a framework to understand how toxins recognize receptors, penetrate membranes and interact with and modify intracellular substrates Bacterial Toxins Bacterial Proteins Toxines bactériennes MEDICAL / Pharmacology bisacsh Bacterial toxins fast Bacterial toxins Proteintoxin (DE-588)4811458-3 gnd rswk-swf Bakteriengift (DE-588)4130547-4 gnd rswk-swf Bakteriengift (DE-588)4130547-4 s Proteintoxin (DE-588)4811458-3 s DE-604 Alouf, Joseph E. edt Erscheint auch als Druck-Ausgabe 978-0-12-800188-2 Erscheint auch als Druck-Ausgabe 0128001887 http://www.sciencedirect.com/science/book/9780128001882 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | The comprehensive sourcebook of bacterial protein toxins Bacterial Toxins Bacterial Proteins Toxines bactériennes MEDICAL / Pharmacology bisacsh Bacterial toxins fast Bacterial toxins Proteintoxin (DE-588)4811458-3 gnd Bakteriengift (DE-588)4130547-4 gnd |
| subject_GND | (DE-588)4811458-3 (DE-588)4130547-4 |
| title | The comprehensive sourcebook of bacterial protein toxins |
| title_alt | Bacterial protein toxins |
| title_auth | The comprehensive sourcebook of bacterial protein toxins |
| title_exact_search | The comprehensive sourcebook of bacterial protein toxins |
| title_full | The comprehensive sourcebook of bacterial protein toxins [edited by] Joseph E. Alouf, Institut Pasteur, Paris, France, Daniel Ladant, Institut Pasteur, Unité de Biochimie des Interactions Moléculaires, Paris France [and] Michel R. Popoff, Instit Pasteur, Unité des Bactéries anaérobies et Toxines, Paris, France |
| title_fullStr | The comprehensive sourcebook of bacterial protein toxins [edited by] Joseph E. Alouf, Institut Pasteur, Paris, France, Daniel Ladant, Institut Pasteur, Unité de Biochimie des Interactions Moléculaires, Paris France [and] Michel R. Popoff, Instit Pasteur, Unité des Bactéries anaérobies et Toxines, Paris, France |
| title_full_unstemmed | The comprehensive sourcebook of bacterial protein toxins [edited by] Joseph E. Alouf, Institut Pasteur, Paris, France, Daniel Ladant, Institut Pasteur, Unité de Biochimie des Interactions Moléculaires, Paris France [and] Michel R. Popoff, Instit Pasteur, Unité des Bactéries anaérobies et Toxines, Paris, France |
| title_short | The comprehensive sourcebook of bacterial protein toxins |
| title_sort | the comprehensive sourcebook of bacterial protein toxins |
| topic | Bacterial Toxins Bacterial Proteins Toxines bactériennes MEDICAL / Pharmacology bisacsh Bacterial toxins fast Bacterial toxins Proteintoxin (DE-588)4811458-3 gnd Bakteriengift (DE-588)4130547-4 gnd |
| topic_facet | Bacterial Toxins Bacterial Proteins Toxines bactériennes MEDICAL / Pharmacology Bacterial toxins Proteintoxin Bakteriengift |
| url | http://www.sciencedirect.com/science/book/9780128001882 |
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