Technological and Medical Implications of Metabolic Control Analysis:
Two decades have passed since the mechanisms of protein synthesis became well enough understood to permit the genetic modification oforganisms. An impressive amount of new knowledge has emerged from the new technology, but much ofthe promise of20years ago has notyet been fulfilled. In biotechnology,...
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Weitere Verfasser: | , |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Dordrecht
Springer Netherlands
2000
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Schriftenreihe: | NATO Science Series, Series 3. High Technology
74 |
Schlagworte: | |
Online-Zugang: | UBT01 URL des Erstveröffentlichers |
Zusammenfassung: | Two decades have passed since the mechanisms of protein synthesis became well enough understood to permit the genetic modification oforganisms. An impressive amount of new knowledge has emerged from the new technology, but much ofthe promise of20years ago has notyet been fulfilled. In biotechnology, efforts to increase the yields of commercially valuable metabolites have been less successful than ex pected, and when they have succeeded it has often been as much from selective breeding as from new methods. The cell is more complicated than what is presented in the classical teaching of biochemistry, it contains more structure than was dreamed of 20 years ago, and the behaviour ofany systemofenzymes is more elaborate than can be explained in terms ofa single supposedly rate-limiting enzyme. Even if classical enzymology and meta bolism may have seemed rather unfashionable during the rise ofmolecular biology, they remain central to any modification ofthe metabolic behaviour oforganisms. As such modification is essential in much ofbiotechnology and drug development, bio technologists can only ignore these topics at their peril |
Beschreibung: | 1 Online-Ressource (XIV, 374 p. 82 illus) |
ISBN: | 9789401140720 |
DOI: | 10.1007/978-94-011-4072-0 |
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Datensatz im Suchindex
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any_adam_object | |
author2 | Cornish-Bowden, Athel Cárdenas, María Luz |
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spelling | Technological and Medical Implications of Metabolic Control Analysis edited by Athel Cornish-Bowden, María Luz Cárdenas Proceedings of the NATO Advanced Research Workshop, Visegrád, Hungary, 10-16 April 1999 Dordrecht Springer Netherlands 2000 1 Online-Ressource (XIV, 374 p. 82 illus) txt rdacontent c rdamedia cr rdacarrier NATO Science Series, Series 3. High Technology 74 Two decades have passed since the mechanisms of protein synthesis became well enough understood to permit the genetic modification oforganisms. An impressive amount of new knowledge has emerged from the new technology, but much ofthe promise of20years ago has notyet been fulfilled. In biotechnology, efforts to increase the yields of commercially valuable metabolites have been less successful than ex pected, and when they have succeeded it has often been as much from selective breeding as from new methods. The cell is more complicated than what is presented in the classical teaching of biochemistry, it contains more structure than was dreamed of 20 years ago, and the behaviour ofany systemofenzymes is more elaborate than can be explained in terms ofa single supposedly rate-limiting enzyme. Even if classical enzymology and meta bolism may have seemed rather unfashionable during the rise ofmolecular biology, they remain central to any modification ofthe metabolic behaviour oforganisms. As such modification is essential in much ofbiotechnology and drug development, bio technologists can only ignore these topics at their peril Medicine & Public Health Internal Medicine Biochemistry, general Cancer Research Mathematical and Computational Biology Medicine Cancer research Internal medicine Biochemistry Biomathematics Stoffwechselkrankheit (DE-588)4057700-4 gnd rswk-swf Stoffwechsel (DE-588)4057699-1 gnd rswk-swf Stoffwechselstörung (DE-588)4057701-6 gnd rswk-swf Regulation (DE-588)4049075-0 gnd rswk-swf Biotechnologie (DE-588)4069491-4 gnd rswk-swf 1\p (DE-588)1071861417 Konferenzschrift 1999 Visegrád gnd-content Stoffwechselstörung (DE-588)4057701-6 s Stoffwechselkrankheit (DE-588)4057700-4 s 2\p DE-604 Stoffwechsel (DE-588)4057699-1 s Biotechnologie (DE-588)4069491-4 s 3\p DE-604 Regulation (DE-588)4049075-0 s 4\p DE-604 Cornish-Bowden, Athel edt Cárdenas, María Luz edt Erscheint auch als Druck-Ausgabe 9780792361893 https://doi.org/10.1007/978-94-011-4072-0 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 3\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 4\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
spellingShingle | Technological and Medical Implications of Metabolic Control Analysis Medicine & Public Health Internal Medicine Biochemistry, general Cancer Research Mathematical and Computational Biology Medicine Cancer research Internal medicine Biochemistry Biomathematics Stoffwechselkrankheit (DE-588)4057700-4 gnd Stoffwechsel (DE-588)4057699-1 gnd Stoffwechselstörung (DE-588)4057701-6 gnd Regulation (DE-588)4049075-0 gnd Biotechnologie (DE-588)4069491-4 gnd |
subject_GND | (DE-588)4057700-4 (DE-588)4057699-1 (DE-588)4057701-6 (DE-588)4049075-0 (DE-588)4069491-4 (DE-588)1071861417 |
title | Technological and Medical Implications of Metabolic Control Analysis |
title_alt | Proceedings of the NATO Advanced Research Workshop, Visegrád, Hungary, 10-16 April 1999 |
title_auth | Technological and Medical Implications of Metabolic Control Analysis |
title_exact_search | Technological and Medical Implications of Metabolic Control Analysis |
title_full | Technological and Medical Implications of Metabolic Control Analysis edited by Athel Cornish-Bowden, María Luz Cárdenas |
title_fullStr | Technological and Medical Implications of Metabolic Control Analysis edited by Athel Cornish-Bowden, María Luz Cárdenas |
title_full_unstemmed | Technological and Medical Implications of Metabolic Control Analysis edited by Athel Cornish-Bowden, María Luz Cárdenas |
title_short | Technological and Medical Implications of Metabolic Control Analysis |
title_sort | technological and medical implications of metabolic control analysis |
topic | Medicine & Public Health Internal Medicine Biochemistry, general Cancer Research Mathematical and Computational Biology Medicine Cancer research Internal medicine Biochemistry Biomathematics Stoffwechselkrankheit (DE-588)4057700-4 gnd Stoffwechsel (DE-588)4057699-1 gnd Stoffwechselstörung (DE-588)4057701-6 gnd Regulation (DE-588)4049075-0 gnd Biotechnologie (DE-588)4069491-4 gnd |
topic_facet | Medicine & Public Health Internal Medicine Biochemistry, general Cancer Research Mathematical and Computational Biology Medicine Cancer research Internal medicine Biochemistry Biomathematics Stoffwechselkrankheit Stoffwechsel Stoffwechselstörung Regulation Biotechnologie Konferenzschrift 1999 Visegrád |
url | https://doi.org/10.1007/978-94-011-4072-0 |
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