Proteomics of Microorganisms: Fundamental Aspects and Application
Starting with the discovery of penicillin, other antibiotics, and insulin, the quest for understanding and use of biological systems, i. e. , microorganisms and ani mal tissue, for the production of value products has lead to a dramatic increase in microbiological and bioengineering research in the...
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Weitere Verfasser: | , , , |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Berlin, Heidelberg
Springer Berlin Heidelberg
2003
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Schriftenreihe: | Advances in Biochemical Engineering/Biotechnology
83 |
Schlagworte: | |
Online-Zugang: | UBT01 Volltext |
Zusammenfassung: | Starting with the discovery of penicillin, other antibiotics, and insulin, the quest for understanding and use of biological systems, i. e. , microorganisms and ani mal tissue, for the production of value products has lead to a dramatic increase in microbiological and bioengineering research in the last decades. Chemical and pharmaceutical companies quickly realized the huge commercial potential of these bioproducts and have spent millions of US dollars on R &D as well as on a build up of production facilities. Although there was limited knowledge about the cell's molecular mechanisms, which are the basis for the formation of the desired products, products from fermentation and extraction of biological matrices were a success right from the start. R&D projects within industry and academia on the continuous improvement of production processes, especially microbial productivity and down stream processing, allowed a fast return of investment and secured competitiveness in the market. Whereas the focus of such research projects was mainly on the discovery of strains with higher pro ductivity for the product of interest, e. g. , antibiotics, a lot of expertise and knowledge was generated allowing the use of biotechnological products and processes outside the pharmaceutical arena. The tremendous increase in knowl edge and the technological developments in microbial genetics where driven by these research projects and, accompanied with the advancements in nucleotide chemistry leading to a much better understanding of intracellular processes, served as a basis for modern molecular biology and recombinant biotech nology |
Beschreibung: | 1 Online-Ressource (XI, 228 p) |
ISBN: | 9783540364597 |
DOI: | 10.1007/3-540-36459-5 |
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520 | |a Starting with the discovery of penicillin, other antibiotics, and insulin, the quest for understanding and use of biological systems, i. e. , microorganisms and ani mal tissue, for the production of value products has lead to a dramatic increase in microbiological and bioengineering research in the last decades. Chemical and pharmaceutical companies quickly realized the huge commercial potential of these bioproducts and have spent millions of US dollars on R &D as well as on a build up of production facilities. Although there was limited knowledge about the cell's molecular mechanisms, which are the basis for the formation of the desired products, products from fermentation and extraction of biological matrices were a success right from the start. R&D projects within industry and academia on the continuous improvement of production processes, especially microbial productivity and down stream processing, allowed a fast return of investment and secured competitiveness in the market. Whereas the focus of such research projects was mainly on the discovery of strains with higher pro ductivity for the product of interest, e. g. , antibiotics, a lot of expertise and knowledge was generated allowing the use of biotechnological products and processes outside the pharmaceutical arena. The tremendous increase in knowl edge and the technological developments in microbial genetics where driven by these research projects and, accompanied with the advancements in nucleotide chemistry leading to a much better understanding of intracellular processes, served as a basis for modern molecular biology and recombinant biotech nology | ||
650 | 4 | |a Life Sciences | |
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650 | 4 | |a Life sciences | |
650 | 4 | |a Biotechnology | |
650 | 4 | |a Chemical engineering | |
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Datensatz im Suchindex
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any_adam_object | |
author2 | Hecker, M. Müllner, Stefan Cahill, D. J. Cash, P. |
author2_role | edt edt edt edt |
author2_variant | m h mh s m sm d j c dj djc p c pc |
author_facet | Hecker, M. Müllner, Stefan Cahill, D. J. Cash, P. |
building | Verbundindex |
bvnumber | BV045151936 |
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collection | ZDB-2-CMS |
ctrlnum | (ZDB-2-CMS)978-3-540-36459-7 (OCoLC)850829807 (DE-599)BVBBV045151936 |
dewey-full | 579 |
dewey-hundreds | 500 - Natural sciences and mathematics |
dewey-ones | 579 - Microorganisms, fungi & algae |
dewey-raw | 579 |
dewey-search | 579 |
dewey-sort | 3579 |
dewey-tens | 570 - Biology |
discipline | Biologie |
doi_str_mv | 10.1007/3-540-36459-5 |
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spelling | Proteomics of Microorganisms Fundamental Aspects and Application edited by M. Hecker, Stefan Müllner, D. J. Cahill, P. Cash, S. J. Cordwell, M. Hecker, H. E. Meyer, M. Mreyen, E. Nordhoff, A. S. Nouwens, W. Schubert, A. Sickmann, R. A. VanBogelen, B. J. Walsh Berlin, Heidelberg Springer Berlin Heidelberg 2003 1 Online-Ressource (XI, 228 p) txt rdacontent c rdamedia cr rdacarrier Advances in Biochemical Engineering/Biotechnology 83 Starting with the discovery of penicillin, other antibiotics, and insulin, the quest for understanding and use of biological systems, i. e. , microorganisms and ani mal tissue, for the production of value products has lead to a dramatic increase in microbiological and bioengineering research in the last decades. Chemical and pharmaceutical companies quickly realized the huge commercial potential of these bioproducts and have spent millions of US dollars on R &D as well as on a build up of production facilities. Although there was limited knowledge about the cell's molecular mechanisms, which are the basis for the formation of the desired products, products from fermentation and extraction of biological matrices were a success right from the start. R&D projects within industry and academia on the continuous improvement of production processes, especially microbial productivity and down stream processing, allowed a fast return of investment and secured competitiveness in the market. Whereas the focus of such research projects was mainly on the discovery of strains with higher pro ductivity for the product of interest, e. g. , antibiotics, a lot of expertise and knowledge was generated allowing the use of biotechnological products and processes outside the pharmaceutical arena. The tremendous increase in knowl edge and the technological developments in microbial genetics where driven by these research projects and, accompanied with the advancements in nucleotide chemistry leading to a much better understanding of intracellular processes, served as a basis for modern molecular biology and recombinant biotech nology Life Sciences Microbiology Biochemistry, general Biotechnology Industrial Chemistry/Chemical Engineering Proteomics Life sciences Chemical engineering Biochemistry Proteom (DE-588)4576155-3 gnd rswk-swf Mikroorganismus (DE-588)4039226-0 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Mikroorganismus (DE-588)4039226-0 s Proteom (DE-588)4576155-3 s 2\p DE-604 Hecker, M. edt Müllner, Stefan edt Cahill, D. J. edt Cash, P. edt Erscheint auch als Druck-Ausgabe 9783540005469 https://doi.org/10.1007/3-540-36459-5 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
spellingShingle | Proteomics of Microorganisms Fundamental Aspects and Application Life Sciences Microbiology Biochemistry, general Biotechnology Industrial Chemistry/Chemical Engineering Proteomics Life sciences Chemical engineering Biochemistry Proteom (DE-588)4576155-3 gnd Mikroorganismus (DE-588)4039226-0 gnd |
subject_GND | (DE-588)4576155-3 (DE-588)4039226-0 (DE-588)4143413-4 |
title | Proteomics of Microorganisms Fundamental Aspects and Application |
title_auth | Proteomics of Microorganisms Fundamental Aspects and Application |
title_exact_search | Proteomics of Microorganisms Fundamental Aspects and Application |
title_full | Proteomics of Microorganisms Fundamental Aspects and Application edited by M. Hecker, Stefan Müllner, D. J. Cahill, P. Cash, S. J. Cordwell, M. Hecker, H. E. Meyer, M. Mreyen, E. Nordhoff, A. S. Nouwens, W. Schubert, A. Sickmann, R. A. VanBogelen, B. J. Walsh |
title_fullStr | Proteomics of Microorganisms Fundamental Aspects and Application edited by M. Hecker, Stefan Müllner, D. J. Cahill, P. Cash, S. J. Cordwell, M. Hecker, H. E. Meyer, M. Mreyen, E. Nordhoff, A. S. Nouwens, W. Schubert, A. Sickmann, R. A. VanBogelen, B. J. Walsh |
title_full_unstemmed | Proteomics of Microorganisms Fundamental Aspects and Application edited by M. Hecker, Stefan Müllner, D. J. Cahill, P. Cash, S. J. Cordwell, M. Hecker, H. E. Meyer, M. Mreyen, E. Nordhoff, A. S. Nouwens, W. Schubert, A. Sickmann, R. A. VanBogelen, B. J. Walsh |
title_short | Proteomics of Microorganisms |
title_sort | proteomics of microorganisms fundamental aspects and application |
title_sub | Fundamental Aspects and Application |
topic | Life Sciences Microbiology Biochemistry, general Biotechnology Industrial Chemistry/Chemical Engineering Proteomics Life sciences Chemical engineering Biochemistry Proteom (DE-588)4576155-3 gnd Mikroorganismus (DE-588)4039226-0 gnd |
topic_facet | Life Sciences Microbiology Biochemistry, general Biotechnology Industrial Chemistry/Chemical Engineering Proteomics Life sciences Chemical engineering Biochemistry Proteom Mikroorganismus Aufsatzsammlung |
url | https://doi.org/10.1007/3-540-36459-5 |
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