Characterization of Compounds in Solution: Theory and Practice
Scientists from many disciplines require making observations which are dependent upon the behavior of compounds in solution. This ranges from areas in geography, such as oceanography, to areas in chemistry, such as chromatography, to areas in biology, such as pharmacology. Historically, information...
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Boston, MA
Springer US
2001
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| Schlagworte: | |
| Online-Zugang: | UBT01 Volltext |
| Zusammenfassung: | Scientists from many disciplines require making observations which are dependent upon the behavior of compounds in solution. This ranges from areas in geography, such as oceanography, to areas in chemistry, such as chromatography, to areas in biology, such as pharmacology. Historically, information would be obtained by observing a response for a given set of conditions and then the conditions would be changed and a new response obtained. In this approach there would be little effort made to actually understand how a compound was behaving in solution but rather just the response was noted. Understanding the behavior of compounds in solution is critical to understanding their behavior in biological systems. This has become increasingly important during the last twenty years as an understanding of the biochemistry related to human illness has become better understood. The development of the pharmaceutical industry and the need to rapidly screen large numbers of compounds has made scientists in the area of drug development aware that the pharmacological activity of compounds can be predicted by knowing their solution physical chemical properties. This is not to say that a specific drug-active site interaction can be predicted but rather a prediction can be made whether or not a compound will be absorbed, transported, or distributed within a physiological system in such a way that an interaction can occur |
| Beschreibung: | 1 Online-Ressource (XVII, 273 p) |
| ISBN: | 9781461513452 |
| DOI: | 10.1007/978-1-4615-1345-2 |
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| 520 | |a Scientists from many disciplines require making observations which are dependent upon the behavior of compounds in solution. This ranges from areas in geography, such as oceanography, to areas in chemistry, such as chromatography, to areas in biology, such as pharmacology. Historically, information would be obtained by observing a response for a given set of conditions and then the conditions would be changed and a new response obtained. In this approach there would be little effort made to actually understand how a compound was behaving in solution but rather just the response was noted. Understanding the behavior of compounds in solution is critical to understanding their behavior in biological systems. This has become increasingly important during the last twenty years as an understanding of the biochemistry related to human illness has become better understood. The development of the pharmaceutical industry and the need to rapidly screen large numbers of compounds has made scientists in the area of drug development aware that the pharmacological activity of compounds can be predicted by knowing their solution physical chemical properties. This is not to say that a specific drug-active site interaction can be predicted but rather a prediction can be made whether or not a compound will be absorbed, transported, or distributed within a physiological system in such a way that an interaction can occur | ||
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Datensatz im Suchindex
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| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 543 - Analytical chemistry |
| dewey-raw | 543 |
| dewey-search | 543 |
| dewey-sort | 3543 |
| dewey-tens | 540 - Chemistry and allied sciences |
| discipline | Chemie / Pharmazie |
| doi_str_mv | 10.1007/978-1-4615-1345-2 |
| format | Electronic eBook |
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| id | DE-604.BV045151869 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:10:06Z |
| institution | BVB |
| isbn | 9781461513452 |
| language | English |
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| spelling | Streng, William H. Verfasser aut Characterization of Compounds in Solution Theory and Practice by William H. Streng Boston, MA Springer US 2001 1 Online-Ressource (XVII, 273 p) txt rdacontent c rdamedia cr rdacarrier Scientists from many disciplines require making observations which are dependent upon the behavior of compounds in solution. This ranges from areas in geography, such as oceanography, to areas in chemistry, such as chromatography, to areas in biology, such as pharmacology. Historically, information would be obtained by observing a response for a given set of conditions and then the conditions would be changed and a new response obtained. In this approach there would be little effort made to actually understand how a compound was behaving in solution but rather just the response was noted. Understanding the behavior of compounds in solution is critical to understanding their behavior in biological systems. This has become increasingly important during the last twenty years as an understanding of the biochemistry related to human illness has become better understood. The development of the pharmaceutical industry and the need to rapidly screen large numbers of compounds has made scientists in the area of drug development aware that the pharmacological activity of compounds can be predicted by knowing their solution physical chemical properties. This is not to say that a specific drug-active site interaction can be predicted but rather a prediction can be made whether or not a compound will be absorbed, transported, or distributed within a physiological system in such a way that an interaction can occur Chemistry Analytical Chemistry Biochemistry, general Physical Chemistry Pharmacy Organic Chemistry Analytical chemistry Organic chemistry Physical chemistry Biochemistry Erscheint auch als Druck-Ausgabe 9781461355083 https://doi.org/10.1007/978-1-4615-1345-2 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Streng, William H. Characterization of Compounds in Solution Theory and Practice Chemistry Analytical Chemistry Biochemistry, general Physical Chemistry Pharmacy Organic Chemistry Analytical chemistry Organic chemistry Physical chemistry Biochemistry |
| title | Characterization of Compounds in Solution Theory and Practice |
| title_auth | Characterization of Compounds in Solution Theory and Practice |
| title_exact_search | Characterization of Compounds in Solution Theory and Practice |
| title_full | Characterization of Compounds in Solution Theory and Practice by William H. Streng |
| title_fullStr | Characterization of Compounds in Solution Theory and Practice by William H. Streng |
| title_full_unstemmed | Characterization of Compounds in Solution Theory and Practice by William H. Streng |
| title_short | Characterization of Compounds in Solution |
| title_sort | characterization of compounds in solution theory and practice |
| title_sub | Theory and Practice |
| topic | Chemistry Analytical Chemistry Biochemistry, general Physical Chemistry Pharmacy Organic Chemistry Analytical chemistry Organic chemistry Physical chemistry Biochemistry |
| topic_facet | Chemistry Analytical Chemistry Biochemistry, general Physical Chemistry Pharmacy Organic Chemistry Analytical chemistry Organic chemistry Physical chemistry Biochemistry |
| url | https://doi.org/10.1007/978-1-4615-1345-2 |
| work_keys_str_mv | AT strengwilliamh characterizationofcompoundsinsolutiontheoryandpractice |