Classical Mechanics and Electromagnetism in Accelerator Physics:
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Cham
Springer
[2018]
|
| Schriftenreihe: | Graduate Texts in Physics
|
| Schlagworte: | |
| Online-Zugang: | TUM01 UBM01 UBT01 UER01 Volltext Inhaltsverzeichnis |
| Beschreibung: | 1 Online-Ressource (X, 280 p. 77 illus., 74 illus. in color) |
| ISBN: | 9783319901886 |
| DOI: | 10.1007/978-3-319-90188-6 |
Internformat
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Datensatz im Suchindex
| _version_ | 1804178581897609216 |
|---|---|
| adam_text | INHALTSVERZEICHNIS
ZUSAMMENFASSUNG 1
ABSTRACT 3
1 EINLEITUNG 5
1.1 UEBERBLICK UEBER DAS IMMUNSYSTEM 5
1.2 T ZELL-VERMITTELTE IMMUNITAET 6
1.2.1 ANTIGENPRAESENTATION AN T ZELLEN 6
1.2.2 AKTIVIERUNG VON NAIVEN T ZELLEN 8
1.2.3 DIE DIFFERENZIERUNG VON NAIVEN CD8* T ZELLEN IN EFFEKTOR T ZELLEN
10
1.3 ENTWICKLUNG VON T ZELL-GEDACHTNIS 12
1.3.1 DIE VORLAEUFER VON GEDAECHTNIS T ZELLEN 12
1.3.2 DIE HETEROGENITAETVON CD8* GEDAECHTNIS T ZELLEN 14
1.3.3 TRANSKRIPTIONELLE KONTROLLE DER ENTWICKLUNG VON CD8* GEDAECHTNIS T
ZELLEN 17
1.4 T ZELL-TOLERANZ 19
1.4.1 ZENTRALE TOLERANZ 19
1.4.2 PERIPHERE TOLERANZ 20
1.5 DIE LEBER ALS IMMUNOLOGISCHES ORGAN 22
1.5.1 DIE ANTIGEN-PRAESENTIERENDEN ZELLPOPULATIONEN DER LEBER 23
1.5.2 ANTIGENPRAESENTATION UND INDUKTION VON PERIPHERER TOLERANZ IN DER
LEBER 25
2 ZIELE DER ARBEIT 27
3 MATERIAL UND METHODEN 29
3.1 MATERIAL 29
3.1.1 GERAETE 29
3.1.2 CHEMIKALIEN UND REAGENZIEN 30
3.1.3 ALLGEMEINE LOESUNGEN 32
3.1.4 KIT SYSTEME 34
3.1.5 ANTIKOERPER 34
3.1.6 FLUOROCHROME 36
3.1.7 PRIMER 37
3.1.8 BESCHICHTETE PARTIKEL 37
3.1.9 ENZYME 37
3.1.10 ZYTOKINE UND CHEMOKINE 38
HTTP://D-NB.INFO/1038772052
3.1.11 ZELLLINIEN 38
3.1.12 MAUSLINIEN 38
3.1.13 REKOMBINANTE BAKTERIEN UND VIREN 39
3.1.14 COMPUTERSOFTWARE 40
3.2 METHODEN 41
3.2.1 ISOLATION VON PRIMAEREN MURINEN ZELLEN 41
3.2.2 ZELLKULTUR 44
3.2.3 HERSTELLUNG VON [BML- C57BL/6] KNOCHENMARKSCHIMAEREN 45
3.2.4 STIMULATION VON T ZELLEN IN VIVO 46
3.2.5 FUNKTIONELLE ANALYSEN VON T ZELLEN IN VITRO 51
3.2.6 DURCHFLUSSZYTOMETRIE 54
3.2.7 IMMUNFLUORESZENZMIKROSKOPIE 56
3.2.8 QUANTITATIVE REAL-TIME PCR 56
3.2.9 ANALYSE DER GLOBALEN GENEXPRESSION VON CD8* T ZELLEN 57
3.2.10 STATISTIK 59
4 ERGEBNISSE 61
4.1 DIE KREUZPRAESENTATION VON LOESLICHEM ANTIGEN DURCH LSEC INDUZIERT
EINE
EIGENSTAENDIGE CD8+ T ZELL-POPULATION 61
4.2 CD8* T ZELLEN WANDERN NACH STIMULATION DURCH LSEC IN LYMPHATISCHE
ORGANE
65
4.3 LSEC-STIMULIERTEN T ZELLEN BESITZEN EIGENSCHAFTEN VON GEDAECHTNIS T
ZELLEN .. 69
4.4 DIE DIFFERENZIERUNG VON LSEC-STIMULIERTEN T ZELLEN IN EFFEKTOR T
ZELLEN BERUHT
AUF EINEM BESTIMMTEN MOLEKULAREN MECHANISMUS 75
4.5 DIE EFFEKTORFUNKTIONEN VON LSEC-STIMULIERTEN T ZELLEN UND GEDAECHTNIS
T ZELLEN SIND VERSCHIEDEN STARK AUSGEPRAEGT 80
4.6 DIE NEUROPILIN-L-EXPRESSION UNTERSCHEIDET ZWISCHEN LSEC-STIMULIERTEN
T ZELLEN UND TCM 84
4.7 DIE STIMULATION NAIVER CD8
+
T ZELLEN DURCH LSEC TRAEGT ZUR ABWEHR VON
INFEKTIONEN BEI 85
5 DISKUSSION 91
5.1 DIE STIMULATION VON NAIVEN CD8+ T ZELLEN DURCH LSEC INDUZIERT WEDER
T ZELL-
DELETION NOCH T ZELL-TOLERANZ 92
5.2 LSEC-STIMULIERTE T ZELLEN BESITZEN EIN HOHES POTENTIAL ZUR
DIFFERENZIERUNG IN
EFFEKTOR T ZELLEN 96
5.3 GEMEINSAMKEITEN UND UNTERSCHIEDE IN DER ENTWICKLUNG VON
LSEC-STIMULIERTEN
T ZELLEN UND TCM 98
5.4 DER MOLEKULARER MECHANISMUS DER REAKTIVIERUNG VON LSEC-STIMULIERTEN
T ZELLEN 101
5.5 DIE ROLLE VON LSEC-STIMULIERTEN T ZELLEN IN DER IMMUNNABWEHR GEGEN
PATHOGENE 106
5.6 NEUROPILIN-1 ALS MARKER FUER LSEC-STIMULIERTE T ZELLEN 109
6 LITERATURVERZEICHNIS 113
7 ABBILDUNGSVERZEICHNIS 129
8 TABELLENVERZEICHNIS 131
9 ABKUERZUNGSVERZEICHNIS 133
|
| any_adam_object | 1 |
| author | Stupakov, Gennady Penn, Gregory |
| author_GND | (DE-588)1121946887 |
| author_facet | Stupakov, Gennady Penn, Gregory |
| author_role | aut aut |
| author_sort | Stupakov, Gennady |
| author_variant | g s gs g p gp |
| building | Verbundindex |
| bvnumber | BV044979762 |
| classification_rvk | UN 6100 |
| classification_tum | PHY 000 |
| collection | ZDB-2-PHA |
| ctrlnum | (ZDB-2-PHA)9783319901886 (OCoLC)1038772052 (DE-599)BVBBV044979762 |
| dewey-full | 531 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 531 - Classical mechanics |
| dewey-raw | 531 |
| dewey-search | 531 |
| dewey-sort | 3531 |
| dewey-tens | 530 - Physics |
| discipline | Physik |
| doi_str_mv | 10.1007/978-3-319-90188-6 |
| format | Electronic eBook |
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| id | DE-604.BV044979762 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:06:15Z |
| institution | BVB |
| isbn | 9783319901886 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-030372155 |
| oclc_num | 1038772052 |
| open_access_boolean | |
| owner | DE-91 DE-BY-TUM DE-29 DE-19 DE-BY-UBM DE-188 DE-703 |
| owner_facet | DE-91 DE-BY-TUM DE-29 DE-19 DE-BY-UBM DE-188 DE-703 |
| physical | 1 Online-Ressource (X, 280 p. 77 illus., 74 illus. in color) |
| psigel | ZDB-2-PHA ZDB-2-PHA_2018 |
| publishDate | 2018 |
| publishDateSearch | 2018 |
| publishDateSort | 2018 |
| publisher | Springer |
| record_format | marc |
| series2 | Graduate Texts in Physics |
| spelling | Stupakov, Gennady Verfasser (DE-588)1121946887 aut Classical Mechanics and Electromagnetism in Accelerator Physics Gennady Stupakov, Gregory Penn Cham Springer [2018] 1 Online-Ressource (X, 280 p. 77 illus., 74 illus. in color) txt rdacontent c rdamedia cr rdacarrier Graduate Texts in Physics Physics Particle acceleration Microwaves Optical engineering Classical Mechanics Microwaves, RF and Optical Engineering Classical Electrodynamics Particle Acceleration and Detection, Beam Physics Teilchenbeschleuniger (DE-588)4059318-6 gnd rswk-swf Elektromagnetismus (DE-588)4014306-5 gnd rswk-swf Mechanik (DE-588)4038168-7 gnd rswk-swf Mechanik (DE-588)4038168-7 s Teilchenbeschleuniger (DE-588)4059318-6 s 1\p DE-604 Elektromagnetismus (DE-588)4014306-5 s 2\p DE-604 Penn, Gregory Verfasser aut Erscheint auch als Druck-Ausgabe 978-3-319-90187-9 https://doi.org/10.1007/978-3-319-90188-6 Verlag URL des Erstveröffentlichers Volltext DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030372155&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Stupakov, Gennady Penn, Gregory Classical Mechanics and Electromagnetism in Accelerator Physics Physics Particle acceleration Microwaves Optical engineering Classical Mechanics Microwaves, RF and Optical Engineering Classical Electrodynamics Particle Acceleration and Detection, Beam Physics Teilchenbeschleuniger (DE-588)4059318-6 gnd Elektromagnetismus (DE-588)4014306-5 gnd Mechanik (DE-588)4038168-7 gnd |
| subject_GND | (DE-588)4059318-6 (DE-588)4014306-5 (DE-588)4038168-7 |
| title | Classical Mechanics and Electromagnetism in Accelerator Physics |
| title_auth | Classical Mechanics and Electromagnetism in Accelerator Physics |
| title_exact_search | Classical Mechanics and Electromagnetism in Accelerator Physics |
| title_full | Classical Mechanics and Electromagnetism in Accelerator Physics Gennady Stupakov, Gregory Penn |
| title_fullStr | Classical Mechanics and Electromagnetism in Accelerator Physics Gennady Stupakov, Gregory Penn |
| title_full_unstemmed | Classical Mechanics and Electromagnetism in Accelerator Physics Gennady Stupakov, Gregory Penn |
| title_short | Classical Mechanics and Electromagnetism in Accelerator Physics |
| title_sort | classical mechanics and electromagnetism in accelerator physics |
| topic | Physics Particle acceleration Microwaves Optical engineering Classical Mechanics Microwaves, RF and Optical Engineering Classical Electrodynamics Particle Acceleration and Detection, Beam Physics Teilchenbeschleuniger (DE-588)4059318-6 gnd Elektromagnetismus (DE-588)4014306-5 gnd Mechanik (DE-588)4038168-7 gnd |
| topic_facet | Physics Particle acceleration Microwaves Optical engineering Classical Mechanics Microwaves, RF and Optical Engineering Classical Electrodynamics Particle Acceleration and Detection, Beam Physics Teilchenbeschleuniger Elektromagnetismus Mechanik |
| url | https://doi.org/10.1007/978-3-319-90188-6 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=030372155&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT stupakovgennady classicalmechanicsandelectromagnetisminacceleratorphysics AT penngregory classicalmechanicsandelectromagnetisminacceleratorphysics |