This volume describes different computational methods encompassing ligand-based approaches (QSAR, pharmcophore), structure-based approaches (homology modeling, docking, molecular dynamics simulation), and combined approaches (virtual screening) with applications in anti-Alzheimer drug design. Differ...

Ausführliche Beschreibung

Bibliographische Detailangaben

Weitere Verfasser:	Roy, Kunal 1971- (HerausgeberIn)
Format:	Elektronisch E-Book
Sprache:	English
Veröffentlicht:	New York, NY Springer New York 2018
Schriftenreihe:	Neuromethods 132
Schlagworte:	Biomedicine Neurosciences Medicine Alzheimerkrankheit Computational chemistry Arzneimitteldesign Aufsatzsammlung
Online-Zugang:	UBR01 TUM01 URL des Erstveröffentlichers
Zusammenfassung:	This volume describes different computational methods encompassing ligand-based approaches (QSAR, pharmcophore), structure-based approaches (homology modeling, docking, molecular dynamics simulation), and combined approaches (virtual screening) with applications in anti-Alzheimer drug design. Different background topics like molecular etiologies of Alzheimer’s disease, targets for new drug development, and different cheminformatic modeling strategies are covered for completeness. Special topics like multi-target drug development, natural products, protein misfolding, and nanomaterials are also included in connection with computational modeling of anti-Alzheimer drug development. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and authoritative, Computational Modeling of Drugs Against Alzheimer’s Disease is a valuable resource for learning about the latest computational techniques used to study this disease
Beschreibung:	1 Online-Ressource (XVII, 645 Seiten) Illustrationen
ISBN:	9781493974047
DOI:	10.1007/978-1-4939-7404-7