Molecular Analysis of Cancer:
Molecular biotechnology has in recent years produced significant advances in finding tumor markers useful in diagnosis and in the assessment of disease progression and prognosis. In Molecular Analysis of Cancer, leading researchers in the field describe in step-by-step detail their best state-of-the...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2002
|
| Schriftenreihe: | Methods in Molecular Medicine
68 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | Molecular biotechnology has in recent years produced significant advances in finding tumor markers useful in diagnosis and in the assessment of disease progression and prognosis. In Molecular Analysis of Cancer, leading researchers in the field describe in step-by-step detail their best state-of-the-art molecular techniques for elucidating the biochemical processes associated with human cancer. Among the techniques presented for identifying chromosomal rearrangements are fluorescent in situ hybridization (FISH), spectral karyotyping (SKY), comparative genomic hybridization (CGH), microsatellite analysis, PCR and RT-PCR, and DNA fingerprinting. Additional methods include SSCP, DGGE, the nonisotopic RNase cleavage assay, and the protein truncation assay and DNA sequencing for identifying mutations. Techniques for the analysis of gene expression include microarray technology and differential display. All these techniques are of great value for identifying genes that are central to cancer development and progression. Comprehensive and state-of-the-art, Molecular Analysis of Cancer not only offers today's researcher a deeper understanding of cancer's molecular pathogenesis, but also provides a detailed examination of each of the major methodologies needed to detect and analyze its associated genetic abnormalities |
| Beschreibung: | 1 Online-Ressource (XII, 304 p) |
| ISBN: | 9781592591350 |
| DOI: | 10.1385/1592591353 |
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| 520 | |a Molecular biotechnology has in recent years produced significant advances in finding tumor markers useful in diagnosis and in the assessment of disease progression and prognosis. In Molecular Analysis of Cancer, leading researchers in the field describe in step-by-step detail their best state-of-the-art molecular techniques for elucidating the biochemical processes associated with human cancer. Among the techniques presented for identifying chromosomal rearrangements are fluorescent in situ hybridization (FISH), spectral karyotyping (SKY), comparative genomic hybridization (CGH), microsatellite analysis, PCR and RT-PCR, and DNA fingerprinting. Additional methods include SSCP, DGGE, the nonisotopic RNase cleavage assay, and the protein truncation assay and DNA sequencing for identifying mutations. Techniques for the analysis of gene expression include microarray technology and differential display. All these techniques are of great value for identifying genes that are central to cancer development and progression. Comprehensive and state-of-the-art, Molecular Analysis of Cancer not only offers today's researcher a deeper understanding of cancer's molecular pathogenesis, but also provides a detailed examination of each of the major methodologies needed to detect and analyze its associated genetic abnormalities | ||
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| spelling | Molecular Analysis of Cancer edited by Jacqueline Boultwood, Carrie Fidler Totowa, NJ Humana Press 2002 1 Online-Ressource (XII, 304 p) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Medicine 68 Molecular biotechnology has in recent years produced significant advances in finding tumor markers useful in diagnosis and in the assessment of disease progression and prognosis. In Molecular Analysis of Cancer, leading researchers in the field describe in step-by-step detail their best state-of-the-art molecular techniques for elucidating the biochemical processes associated with human cancer. Among the techniques presented for identifying chromosomal rearrangements are fluorescent in situ hybridization (FISH), spectral karyotyping (SKY), comparative genomic hybridization (CGH), microsatellite analysis, PCR and RT-PCR, and DNA fingerprinting. Additional methods include SSCP, DGGE, the nonisotopic RNase cleavage assay, and the protein truncation assay and DNA sequencing for identifying mutations. Techniques for the analysis of gene expression include microarray technology and differential display. All these techniques are of great value for identifying genes that are central to cancer development and progression. Comprehensive and state-of-the-art, Molecular Analysis of Cancer not only offers today's researcher a deeper understanding of cancer's molecular pathogenesis, but also provides a detailed examination of each of the major methodologies needed to detect and analyze its associated genetic abnormalities Medicine & Public Health Pathology Medicine Krebs Medizin (DE-588)4073781-0 gnd rswk-swf Molekulare Medizin (DE-588)4543844-4 gnd rswk-swf Krebs Medizin (DE-588)4073781-0 s Molekulare Medizin (DE-588)4543844-4 s DE-604 Boultwood, Jacqueline edt Fidler, Carrie edt Erscheint auch als Druck-Ausgabe 9780896036222 https://doi.org/10.1385/1592591353 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Molecular Analysis of Cancer Medicine & Public Health Pathology Medicine Krebs Medizin (DE-588)4073781-0 gnd Molekulare Medizin (DE-588)4543844-4 gnd |
| subject_GND | (DE-588)4073781-0 (DE-588)4543844-4 |
| title | Molecular Analysis of Cancer |
| title_auth | Molecular Analysis of Cancer |
| title_exact_search | Molecular Analysis of Cancer |
| title_full | Molecular Analysis of Cancer edited by Jacqueline Boultwood, Carrie Fidler |
| title_fullStr | Molecular Analysis of Cancer edited by Jacqueline Boultwood, Carrie Fidler |
| title_full_unstemmed | Molecular Analysis of Cancer edited by Jacqueline Boultwood, Carrie Fidler |
| title_short | Molecular Analysis of Cancer |
| title_sort | molecular analysis of cancer |
| topic | Medicine & Public Health Pathology Medicine Krebs Medizin (DE-588)4073781-0 gnd Molekulare Medizin (DE-588)4543844-4 gnd |
| topic_facet | Medicine & Public Health Pathology Medicine Krebs Medizin Molekulare Medizin |
| url | https://doi.org/10.1385/1592591353 |
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