Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols
How and why certain proteins misfold and how this misfolding is linked to many disease processes has become a well-documented topic of study. Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols moves beyond the basics to emphasize the molecular effects of protein misf...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2010
|
| Schriftenreihe: | Methods in Molecular Biology, Methods and Protocols
648 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | How and why certain proteins misfold and how this misfolding is linked to many disease processes has become a well-documented topic of study. Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols moves beyond the basics to emphasize the molecular effects of protein misfolding at a cellular level, to delineate the impacts and cellular reactions that play a role in pathogenetic mechanisms, and to pinpoint possible manipulations and treatment strategies that can counteract, modify, or delay the consequences of misfolding. The volume begins with several concepts and approaches developed in the recent past including a connection to the research field of aging, where protein misfolding diseases have been equated to premature aging processes, and the book’s coverage continues with detailed descriptions of protocols for relevant experimental approaches. Written in the highly successful Methods in Molecular Biology™ series format, protocols chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols aims to aid researchers in the field, as well as medical professionals and molecular biologists, in shaping and performing research related to this intriguing and vital subject |
| Beschreibung: | 1 Online-Ressource (XI, 330 p. 54 illus., 4 illus. in color) |
| ISBN: | 9781607617563 |
| DOI: | 10.1007/978-1-60761-756-3 |
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Datensatz im Suchindex
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| discipline | Biologie |
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| spelling | Protein Misfolding and Cellular Stress in Disease and Aging Concepts and Protocols edited by Peter Bross, Niels Gregersen Totowa, NJ Humana Press 2010 1 Online-Ressource (XI, 330 p. 54 illus., 4 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology, Methods and Protocols 648 How and why certain proteins misfold and how this misfolding is linked to many disease processes has become a well-documented topic of study. Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols moves beyond the basics to emphasize the molecular effects of protein misfolding at a cellular level, to delineate the impacts and cellular reactions that play a role in pathogenetic mechanisms, and to pinpoint possible manipulations and treatment strategies that can counteract, modify, or delay the consequences of misfolding. The volume begins with several concepts and approaches developed in the recent past including a connection to the research field of aging, where protein misfolding diseases have been equated to premature aging processes, and the book’s coverage continues with detailed descriptions of protocols for relevant experimental approaches. Written in the highly successful Methods in Molecular Biology™ series format, protocols chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols aims to aid researchers in the field, as well as medical professionals and molecular biologists, in shaping and performing research related to this intriguing and vital subject Life Sciences Cell Biology Proteomics Life sciences Cell biology Pathophysiologie (DE-588)4044898-8 gnd rswk-swf Proteinfaltung (DE-588)4324567-5 gnd rswk-swf Konformationsänderung (DE-588)4164966-7 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Proteinfaltung (DE-588)4324567-5 s Konformationsänderung (DE-588)4164966-7 s Pathophysiologie (DE-588)4044898-8 s 2\p DE-604 Bross, Peter edt Gregersen, Niels edt Erscheint auch als Druck-Ausgabe 9781607617556 https://doi.org/10.1007/978-1-60761-756-3 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Protein Misfolding and Cellular Stress in Disease and Aging Concepts and Protocols Life Sciences Cell Biology Proteomics Life sciences Cell biology Pathophysiologie (DE-588)4044898-8 gnd Proteinfaltung (DE-588)4324567-5 gnd Konformationsänderung (DE-588)4164966-7 gnd |
| subject_GND | (DE-588)4044898-8 (DE-588)4324567-5 (DE-588)4164966-7 (DE-588)4143413-4 |
| title | Protein Misfolding and Cellular Stress in Disease and Aging Concepts and Protocols |
| title_auth | Protein Misfolding and Cellular Stress in Disease and Aging Concepts and Protocols |
| title_exact_search | Protein Misfolding and Cellular Stress in Disease and Aging Concepts and Protocols |
| title_full | Protein Misfolding and Cellular Stress in Disease and Aging Concepts and Protocols edited by Peter Bross, Niels Gregersen |
| title_fullStr | Protein Misfolding and Cellular Stress in Disease and Aging Concepts and Protocols edited by Peter Bross, Niels Gregersen |
| title_full_unstemmed | Protein Misfolding and Cellular Stress in Disease and Aging Concepts and Protocols edited by Peter Bross, Niels Gregersen |
| title_short | Protein Misfolding and Cellular Stress in Disease and Aging |
| title_sort | protein misfolding and cellular stress in disease and aging concepts and protocols |
| title_sub | Concepts and Protocols |
| topic | Life Sciences Cell Biology Proteomics Life sciences Cell biology Pathophysiologie (DE-588)4044898-8 gnd Proteinfaltung (DE-588)4324567-5 gnd Konformationsänderung (DE-588)4164966-7 gnd |
| topic_facet | Life Sciences Cell Biology Proteomics Life sciences Cell biology Pathophysiologie Proteinfaltung Konformationsänderung Aufsatzsammlung |
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