DNA Recombination: Methods and Protocols
Homologous recombination is important in various aspects of DNA metabolism, including damage repair, replication, telomere maintenance, and meiosis, and yeast genetics has successfully provided a framework for the mechanism of homologous recombination. Divided into four convenient sections, DNA Reco...
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Weitere Verfasser: | |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Totowa, NJ
Humana Press
2011
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Ausgabe: | 1 |
Schriftenreihe: | Methods in Molecular Biology, Methods and Protocols
745 |
Schlagworte: | |
Online-Zugang: | UBR01 TUM01 Volltext |
Zusammenfassung: | Homologous recombination is important in various aspects of DNA metabolism, including damage repair, replication, telomere maintenance, and meiosis, and yeast genetics has successfully provided a framework for the mechanism of homologous recombination. Divided into four convenient sections, DNA Recombination: Methods and Protocols covers recent techniques that best utilize the advantages of the yeast system, prescribing to the belief that yeast will keep serving as a great model organism to study homologous recombination. Chapters have also been included for such exceptions as the group of genes involved in recombination that are found solely in higher eukaryotes, such as BRCA2. And looking forward, a necessary step in the direction of understanding the homologous recombination process is to isolate the machine and let it work in a test tube. Understanding the design by studying the appearance and behavior of the machinery as a single molecule will be an important milestone toward understanding the mechanism of action of the machinery. Techniques covering these topics have also been included. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, DNA Recombination: Methods and Protocols serves as an ideal guide to scientists of all backgrounds with its well-honed methodologies and strives to bring the reader to the next level of understanding regarding this vital subject |
Beschreibung: | 1 Online-Ressource (XIV, 565 p. 119 illus., 3 illus. in color) |
ISBN: | 9781617791291 |
DOI: | 10.1007/978-1-61779-129-1 |
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spelling | DNA Recombination Methods and Protocols edited by Hideo Tsubouchi 1 Totowa, NJ Humana Press 2011 1 Online-Ressource (XIV, 565 p. 119 illus., 3 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology, Methods and Protocols 745 Homologous recombination is important in various aspects of DNA metabolism, including damage repair, replication, telomere maintenance, and meiosis, and yeast genetics has successfully provided a framework for the mechanism of homologous recombination. Divided into four convenient sections, DNA Recombination: Methods and Protocols covers recent techniques that best utilize the advantages of the yeast system, prescribing to the belief that yeast will keep serving as a great model organism to study homologous recombination. Chapters have also been included for such exceptions as the group of genes involved in recombination that are found solely in higher eukaryotes, such as BRCA2. And looking forward, a necessary step in the direction of understanding the homologous recombination process is to isolate the machine and let it work in a test tube. Understanding the design by studying the appearance and behavior of the machinery as a single molecule will be an important milestone toward understanding the mechanism of action of the machinery. Techniques covering these topics have also been included. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, DNA Recombination: Methods and Protocols serves as an ideal guide to scientists of all backgrounds with its well-honed methodologies and strives to bring the reader to the next level of understanding regarding this vital subject Biomedicine Human Genetics Microbial Genetics and Genomics Medicine Human genetics Microbial genetics Microbial genomics Tsubouchi, Hideo edt Erscheint auch als Druck-Ausgabe 9781617791284 https://doi.org/10.1007/978-1-61779-129-1 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | DNA Recombination Methods and Protocols Biomedicine Human Genetics Microbial Genetics and Genomics Medicine Human genetics Microbial genetics Microbial genomics |
title | DNA Recombination Methods and Protocols |
title_auth | DNA Recombination Methods and Protocols |
title_exact_search | DNA Recombination Methods and Protocols |
title_full | DNA Recombination Methods and Protocols edited by Hideo Tsubouchi |
title_fullStr | DNA Recombination Methods and Protocols edited by Hideo Tsubouchi |
title_full_unstemmed | DNA Recombination Methods and Protocols edited by Hideo Tsubouchi |
title_short | DNA Recombination |
title_sort | dna recombination methods and protocols |
title_sub | Methods and Protocols |
topic | Biomedicine Human Genetics Microbial Genetics and Genomics Medicine Human genetics Microbial genetics Microbial genomics |
topic_facet | Biomedicine Human Genetics Microbial Genetics and Genomics Medicine Human genetics Microbial genetics Microbial genomics |
url | https://doi.org/10.1007/978-1-61779-129-1 |
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