Liver Stem Cells: Methods and Protocols
Increasing evidence suggests that liver stem cells have the capacity to differentiate into parenchymal hepatocytes or into bile ductular cells. These stem cells may be activated to proliferate after severe liver injury or exposure to hepatocarcinogens. Stem cell replacement strategies are being inve...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer New York
2012
|
| Ausgabe: | 1 |
| Schriftenreihe: | Methods in Molecular Biology, Methods and Protocols
826 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | Increasing evidence suggests that liver stem cells have the capacity to differentiate into parenchymal hepatocytes or into bile ductular cells. These stem cells may be activated to proliferate after severe liver injury or exposure to hepatocarcinogens. Stem cell replacement strategies are being investigated as an alternative approach to liver repair and regeneration. Additionally, stem cell transplantation has been shown to significantly improve liver function and increase survival in experimentally-induced liver-injury models in animals. In Liver Stem Cells: Methods and Protocols, expert researchers focus on several hepatic progenitor cells, hepatic differentiation form stem cells, bile ductal cell formation from stem cells, liver stem cells and hepatocarcinogenesi, and application of liver stem cells for cell therapy. These topics shed light on stem cell technology which may lead to the development of effective clinical modalities for human liver diseases. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Thorough and intuitive, Liver Stem Cells: Methods and Protocols seeks to aid scientists in the further study of preclinical and clinical investigations that explore the therapeutic potential of stem cells in repair of liver injuries |
| Beschreibung: | 1 Online-Ressource (X, 226 p. 59 illus., 10 illus. in color) |
| ISBN: | 9781617794681 |
| DOI: | 10.1007/978-1-61779-468-1 |
Internformat
MARC
| LEADER | 00000nmm a2200000zcb4500 | ||
|---|---|---|---|
| 001 | BV044952320 | ||
| 003 | DE-604 | ||
| 005 | 20181016 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 180517s2012 |||| o||u| ||||||eng d | ||
| 020 | |a 9781617794681 |9 978-1-61779-468-1 | ||
| 024 | 7 | |a 10.1007/978-1-61779-468-1 |2 doi | |
| 035 | |a (ZDB-2-PRO)978-1-61779-468-1 | ||
| 035 | |a (OCoLC)820518229 | ||
| 035 | |a (DE-599)BVBBV044952320 | ||
| 040 | |a DE-604 |b ger |e rda | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-355 |a DE-91 | ||
| 082 | 0 | |a 571.6 |2 23 | |
| 084 | |a WX 6600 |0 (DE-625)152214:13423 |2 rvk | ||
| 084 | |a YU 5558 |0 (DE-625)154204:12965 |2 rvk | ||
| 245 | 1 | 0 | |a Liver Stem Cells |b Methods and Protocols |c edited by Takahiro Ochiya |
| 250 | |a 1 | ||
| 264 | 1 | |a New York, NY |b Springer New York |c 2012 | |
| 300 | |a 1 Online-Ressource (X, 226 p. 59 illus., 10 illus. in color) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 490 | 0 | |a Methods in Molecular Biology, Methods and Protocols |v 826 | |
| 520 | |a Increasing evidence suggests that liver stem cells have the capacity to differentiate into parenchymal hepatocytes or into bile ductular cells. These stem cells may be activated to proliferate after severe liver injury or exposure to hepatocarcinogens. Stem cell replacement strategies are being investigated as an alternative approach to liver repair and regeneration. Additionally, stem cell transplantation has been shown to significantly improve liver function and increase survival in experimentally-induced liver-injury models in animals. In Liver Stem Cells: Methods and Protocols, expert researchers focus on several hepatic progenitor cells, hepatic differentiation form stem cells, bile ductal cell formation from stem cells, liver stem cells and hepatocarcinogenesi, and application of liver stem cells for cell therapy. These topics shed light on stem cell technology which may lead to the development of effective clinical modalities for human liver diseases. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Thorough and intuitive, Liver Stem Cells: Methods and Protocols seeks to aid scientists in the further study of preclinical and clinical investigations that explore the therapeutic potential of stem cells in repair of liver injuries | ||
| 650 | 4 | |a Life Sciences | |
| 650 | 4 | |a Cell Biology | |
| 650 | 4 | |a Stem Cells | |
| 650 | 4 | |a Life sciences | |
| 650 | 4 | |a Cell biology | |
| 650 | 4 | |a Stem cells | |
| 650 | 0 | 7 | |a Labortechnik |0 (DE-588)4123602-6 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Stammzelle |0 (DE-588)4665329-6 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Leber |0 (DE-588)4034933-0 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Leber |0 (DE-588)4034933-0 |D s |
| 689 | 0 | 1 | |a Stammzelle |0 (DE-588)4665329-6 |D s |
| 689 | 0 | 2 | |a Labortechnik |0 (DE-588)4123602-6 |D s |
| 689 | 0 | |C b |5 DE-604 | |
| 700 | 1 | |a Ochiya, Takahiro |4 edt | |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9781617794674 |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-1-61779-468-1 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
| 912 | |a ZDB-2-PRO | ||
| 999 | |a oai:aleph.bib-bvb.de:BVB01-030345075 | ||
| 966 | e | |u https://doi.org/10.1007/978-1-61779-468-1 |l UBR01 |p ZDB-2-PRO |x Verlag |3 Volltext | |
| 966 | e | |u https://doi.org/10.1007/978-1-61779-468-1 |l TUM01 |p ZDB-2-PRO |x Verlag |3 Volltext | |
Datensatz im Suchindex
| _version_ | 1804178542029701120 |
|---|---|
| any_adam_object | |
| author2 | Ochiya, Takahiro |
| author2_role | edt |
| author2_variant | t o to |
| author_facet | Ochiya, Takahiro |
| building | Verbundindex |
| bvnumber | BV044952320 |
| classification_rvk | WX 6600 YU 5558 |
| collection | ZDB-2-PRO |
| ctrlnum | (ZDB-2-PRO)978-1-61779-468-1 (OCoLC)820518229 (DE-599)BVBBV044952320 |
| dewey-full | 571.6 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 571 - Physiology & related subjects |
| dewey-raw | 571.6 |
| dewey-search | 571.6 |
| dewey-sort | 3571.6 |
| dewey-tens | 570 - Biology |
| discipline | Biologie Medizin |
| doi_str_mv | 10.1007/978-1-61779-468-1 |
| edition | 1 |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03532nmm a2200565zcb4500</leader><controlfield tag="001">BV044952320</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20181016 </controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">180517s2012 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781617794681</subfield><subfield code="9">978-1-61779-468-1</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/978-1-61779-468-1</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-2-PRO)978-1-61779-468-1</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)820518229</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV044952320</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield><subfield code="a">DE-91</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">571.6</subfield><subfield code="2">23</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WX 6600</subfield><subfield code="0">(DE-625)152214:13423</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">YU 5558</subfield><subfield code="0">(DE-625)154204:12965</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Liver Stem Cells</subfield><subfield code="b">Methods and Protocols</subfield><subfield code="c">edited by Takahiro Ochiya</subfield></datafield><datafield tag="250" ind1=" " ind2=" "><subfield code="a">1</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">New York, NY</subfield><subfield code="b">Springer New York</subfield><subfield code="c">2012</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (X, 226 p. 59 illus., 10 illus. in color)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Methods in Molecular Biology, Methods and Protocols</subfield><subfield code="v">826</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Increasing evidence suggests that liver stem cells have the capacity to differentiate into parenchymal hepatocytes or into bile ductular cells. These stem cells may be activated to proliferate after severe liver injury or exposure to hepatocarcinogens. Stem cell replacement strategies are being investigated as an alternative approach to liver repair and regeneration. Additionally, stem cell transplantation has been shown to significantly improve liver function and increase survival in experimentally-induced liver-injury models in animals. In Liver Stem Cells: Methods and Protocols, expert researchers focus on several hepatic progenitor cells, hepatic differentiation form stem cells, bile ductal cell formation from stem cells, liver stem cells and hepatocarcinogenesi, and application of liver stem cells for cell therapy. These topics shed light on stem cell technology which may lead to the development of effective clinical modalities for human liver diseases. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Thorough and intuitive, Liver Stem Cells: Methods and Protocols seeks to aid scientists in the further study of preclinical and clinical investigations that explore the therapeutic potential of stem cells in repair of liver injuries</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Life Sciences</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cell Biology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Stem Cells</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Life sciences</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cell biology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Stem cells</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Labortechnik</subfield><subfield code="0">(DE-588)4123602-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Stammzelle</subfield><subfield code="0">(DE-588)4665329-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Leber</subfield><subfield code="0">(DE-588)4034933-0</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Leber</subfield><subfield code="0">(DE-588)4034933-0</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Stammzelle</subfield><subfield code="0">(DE-588)4665329-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="2"><subfield code="a">Labortechnik</subfield><subfield code="0">(DE-588)4123602-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="C">b</subfield><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ochiya, Takahiro</subfield><subfield code="4">edt</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9781617794674</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1007/978-1-61779-468-1</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-2-PRO</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-030345075</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-1-61779-468-1</subfield><subfield code="l">UBR01</subfield><subfield code="p">ZDB-2-PRO</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-1-61779-468-1</subfield><subfield code="l">TUM01</subfield><subfield code="p">ZDB-2-PRO</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| id | DE-604.BV044952320 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:05:37Z |
| institution | BVB |
| isbn | 9781617794681 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-030345075 |
| oclc_num | 820518229 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-91 DE-BY-TUM |
| owner_facet | DE-355 DE-BY-UBR DE-91 DE-BY-TUM |
| physical | 1 Online-Ressource (X, 226 p. 59 illus., 10 illus. in color) |
| psigel | ZDB-2-PRO |
| publishDate | 2012 |
| publishDateSearch | 2012 |
| publishDateSort | 2012 |
| publisher | Springer New York |
| record_format | marc |
| series2 | Methods in Molecular Biology, Methods and Protocols |
| spelling | Liver Stem Cells Methods and Protocols edited by Takahiro Ochiya 1 New York, NY Springer New York 2012 1 Online-Ressource (X, 226 p. 59 illus., 10 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology, Methods and Protocols 826 Increasing evidence suggests that liver stem cells have the capacity to differentiate into parenchymal hepatocytes or into bile ductular cells. These stem cells may be activated to proliferate after severe liver injury or exposure to hepatocarcinogens. Stem cell replacement strategies are being investigated as an alternative approach to liver repair and regeneration. Additionally, stem cell transplantation has been shown to significantly improve liver function and increase survival in experimentally-induced liver-injury models in animals. In Liver Stem Cells: Methods and Protocols, expert researchers focus on several hepatic progenitor cells, hepatic differentiation form stem cells, bile ductal cell formation from stem cells, liver stem cells and hepatocarcinogenesi, and application of liver stem cells for cell therapy. These topics shed light on stem cell technology which may lead to the development of effective clinical modalities for human liver diseases. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Thorough and intuitive, Liver Stem Cells: Methods and Protocols seeks to aid scientists in the further study of preclinical and clinical investigations that explore the therapeutic potential of stem cells in repair of liver injuries Life Sciences Cell Biology Stem Cells Life sciences Cell biology Stem cells Labortechnik (DE-588)4123602-6 gnd rswk-swf Stammzelle (DE-588)4665329-6 gnd rswk-swf Leber (DE-588)4034933-0 gnd rswk-swf Leber (DE-588)4034933-0 s Stammzelle (DE-588)4665329-6 s Labortechnik (DE-588)4123602-6 s b DE-604 Ochiya, Takahiro edt Erscheint auch als Druck-Ausgabe 9781617794674 https://doi.org/10.1007/978-1-61779-468-1 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Liver Stem Cells Methods and Protocols Life Sciences Cell Biology Stem Cells Life sciences Cell biology Stem cells Labortechnik (DE-588)4123602-6 gnd Stammzelle (DE-588)4665329-6 gnd Leber (DE-588)4034933-0 gnd |
| subject_GND | (DE-588)4123602-6 (DE-588)4665329-6 (DE-588)4034933-0 |
| title | Liver Stem Cells Methods and Protocols |
| title_auth | Liver Stem Cells Methods and Protocols |
| title_exact_search | Liver Stem Cells Methods and Protocols |
| title_full | Liver Stem Cells Methods and Protocols edited by Takahiro Ochiya |
| title_fullStr | Liver Stem Cells Methods and Protocols edited by Takahiro Ochiya |
| title_full_unstemmed | Liver Stem Cells Methods and Protocols edited by Takahiro Ochiya |
| title_short | Liver Stem Cells |
| title_sort | liver stem cells methods and protocols |
| title_sub | Methods and Protocols |
| topic | Life Sciences Cell Biology Stem Cells Life sciences Cell biology Stem cells Labortechnik (DE-588)4123602-6 gnd Stammzelle (DE-588)4665329-6 gnd Leber (DE-588)4034933-0 gnd |
| topic_facet | Life Sciences Cell Biology Stem Cells Life sciences Cell biology Stem cells Labortechnik Stammzelle Leber |
| url | https://doi.org/10.1007/978-1-61779-468-1 |
| work_keys_str_mv | AT ochiyatakahiro liverstemcellsmethodsandprotocols |