Genotoxicity and DNA Repair: A Practical Approach
Genotoxicity and DNA Repair: A Practical Approach provides a key reference for determining how to analyze the genotoxic activity of molecules or materials and, at the same time, serves as a useful tool for researchers in the Environmental Mutagenesis and DNA Repair fields. Focused on genotoxicity as...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer New York
2014
|
| Schriftenreihe: | Methods in Pharmacology and Toxicology
|
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | Genotoxicity and DNA Repair: A Practical Approach provides a key reference for determining how to analyze the genotoxic activity of molecules or materials and, at the same time, serves as a useful tool for researchers in the Environmental Mutagenesis and DNA Repair fields. Focused on genotoxicity assays recommended by the "OECD guidelines for the testing of chemicals", this volume also covers other useful assays, such as some gene mutation assays, the comet assay in different species and applications, and the SMART assays of Drosophila. For all the assays, the book presents brief theoretical introductions to the topics and updated standard and modified step-by-step protocols to perform them. Special emphasis is placed on the analysis of nanoparticles, including an integrative approach analysis. The DNA Repair section includes several assays that provide information on repair activity in vitro and in vivo, as well as recent applications to study DNA repair in humans, cell cultures, and animal models. As a volume in the Methods in Pharmacology and Toxicology series, the chapters contain the kind of detail and key implementation advice that ensures reproducible results in the lab. Authoritative and invaluable, Genotoxicity and DNA Repair: A Practical Approach aims to aid scientists in their pursuit of forwarding this vital field of study |
| Beschreibung: | 1 Online-Ressource (XII, 483 p. 70 illus., 42 illus. in color) |
| ISBN: | 9781493910687 |
| DOI: | 10.1007/978-1-4939-1068-7 |
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Datensatz im Suchindex
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| spelling | Genotoxicity and DNA Repair A Practical Approach edited by L. María Sierra, Isabel Gaivão New York, NY Springer New York 2014 1 Online-Ressource (XII, 483 p. 70 illus., 42 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Pharmacology and Toxicology Genotoxicity and DNA Repair: A Practical Approach provides a key reference for determining how to analyze the genotoxic activity of molecules or materials and, at the same time, serves as a useful tool for researchers in the Environmental Mutagenesis and DNA Repair fields. Focused on genotoxicity assays recommended by the "OECD guidelines for the testing of chemicals", this volume also covers other useful assays, such as some gene mutation assays, the comet assay in different species and applications, and the SMART assays of Drosophila. For all the assays, the book presents brief theoretical introductions to the topics and updated standard and modified step-by-step protocols to perform them. Special emphasis is placed on the analysis of nanoparticles, including an integrative approach analysis. The DNA Repair section includes several assays that provide information on repair activity in vitro and in vivo, as well as recent applications to study DNA repair in humans, cell cultures, and animal models. As a volume in the Methods in Pharmacology and Toxicology series, the chapters contain the kind of detail and key implementation advice that ensures reproducible results in the lab. Authoritative and invaluable, Genotoxicity and DNA Repair: A Practical Approach aims to aid scientists in their pursuit of forwarding this vital field of study Biomedicine Pharmacology/Toxicology Human Genetics Medicine Human genetics Pharmacology Mutagenität (DE-588)4120777-4 gnd rswk-swf Labortechnik (DE-588)4123602-6 gnd rswk-swf DNS-Reparatur (DE-588)4150347-8 gnd rswk-swf Mutagenität (DE-588)4120777-4 s DNS-Reparatur (DE-588)4150347-8 s Labortechnik (DE-588)4123602-6 s b DE-604 Sierra, L. María edt Gaivão, Isabel edt Erscheint auch als Druck-Ausgabe 9781493910670 https://doi.org/10.1007/978-1-4939-1068-7 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Genotoxicity and DNA Repair A Practical Approach Biomedicine Pharmacology/Toxicology Human Genetics Medicine Human genetics Pharmacology Mutagenität (DE-588)4120777-4 gnd Labortechnik (DE-588)4123602-6 gnd DNS-Reparatur (DE-588)4150347-8 gnd |
| subject_GND | (DE-588)4120777-4 (DE-588)4123602-6 (DE-588)4150347-8 |
| title | Genotoxicity and DNA Repair A Practical Approach |
| title_auth | Genotoxicity and DNA Repair A Practical Approach |
| title_exact_search | Genotoxicity and DNA Repair A Practical Approach |
| title_full | Genotoxicity and DNA Repair A Practical Approach edited by L. María Sierra, Isabel Gaivão |
| title_fullStr | Genotoxicity and DNA Repair A Practical Approach edited by L. María Sierra, Isabel Gaivão |
| title_full_unstemmed | Genotoxicity and DNA Repair A Practical Approach edited by L. María Sierra, Isabel Gaivão |
| title_short | Genotoxicity and DNA Repair |
| title_sort | genotoxicity and dna repair a practical approach |
| title_sub | A Practical Approach |
| topic | Biomedicine Pharmacology/Toxicology Human Genetics Medicine Human genetics Pharmacology Mutagenität (DE-588)4120777-4 gnd Labortechnik (DE-588)4123602-6 gnd DNS-Reparatur (DE-588)4150347-8 gnd |
| topic_facet | Biomedicine Pharmacology/Toxicology Human Genetics Medicine Human genetics Pharmacology Mutagenität Labortechnik DNS-Reparatur |
| url | https://doi.org/10.1007/978-1-4939-1068-7 |
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