Protein Misfolding and Disease: Principles and Protocols
It has now become clear that a large number of diseases with very different pathologies share a common framework of protein misfolding, accompanied by degradation and/or aggregation of the misfolded proteins. In Protein Misfolding and Disease: Principles and Protocols, notable experts in conformatio...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2003
|
| Schriftenreihe: | Methods in Molecular Biology™
232 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | It has now become clear that a large number of diseases with very different pathologies share a common framework of protein misfolding, accompanied by degradation and/or aggregation of the misfolded proteins. In Protein Misfolding and Disease: Principles and Protocols, notable experts in conformational disease review the latest thinking about the molecular processes underlying these diseases and describe cutting-edge biochemical, genomic, cellular, and chemical laboratory techniques for studying their genesis and pathologies. The authors apply their carefully refined methods to a variety of metabolic and neurodegenerative disorders, as well as to the aging process. The techniques presented are broadly applicable in many diverse disease contexts and may be used in both diagnosis and detailed research on new treatment strategies. Each tried and proven protocol includes insightful background notes, lists of required equipment and reagents, step-by-step instructions, and tips on troubleshooting and on how to avoid known pitfalls. Comprehensive and cutting-edge, Protein Misfolding and Disease: Principles and Protocols offers both novice and experienced researchers a solid theoretical grounding in conformational disease and a remarkable set of analytical methodologies for uncovering its characteristics and generating new therapeutic approaches |
| Beschreibung: | 1 Online-Ressource (XV, 318 p) |
| ISBN: | 9781592593941 |
| DOI: | 10.1385/1592593941 |
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| spelling | Protein Misfolding and Disease Principles and Protocols edited by Peter Bross, Niels Gregersen Totowa, NJ Humana Press 2003 1 Online-Ressource (XV, 318 p) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology™ 232 It has now become clear that a large number of diseases with very different pathologies share a common framework of protein misfolding, accompanied by degradation and/or aggregation of the misfolded proteins. In Protein Misfolding and Disease: Principles and Protocols, notable experts in conformational disease review the latest thinking about the molecular processes underlying these diseases and describe cutting-edge biochemical, genomic, cellular, and chemical laboratory techniques for studying their genesis and pathologies. The authors apply their carefully refined methods to a variety of metabolic and neurodegenerative disorders, as well as to the aging process. The techniques presented are broadly applicable in many diverse disease contexts and may be used in both diagnosis and detailed research on new treatment strategies. Each tried and proven protocol includes insightful background notes, lists of required equipment and reagents, step-by-step instructions, and tips on troubleshooting and on how to avoid known pitfalls. Comprehensive and cutting-edge, Protein Misfolding and Disease: Principles and Protocols offers both novice and experienced researchers a solid theoretical grounding in conformational disease and a remarkable set of analytical methodologies for uncovering its characteristics and generating new therapeutic approaches Life Sciences Biochemistry, general Life sciences Biochemistry Degeneration (DE-588)4132275-7 gnd rswk-swf Stoffwechselkrankheit (DE-588)4057700-4 gnd rswk-swf Altern (DE-588)4068596-2 gnd rswk-swf Proteinfaltung (DE-588)4324567-5 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Altern (DE-588)4068596-2 s Proteinfaltung (DE-588)4324567-5 s DE-604 Stoffwechselkrankheit (DE-588)4057700-4 s Degeneration (DE-588)4132275-7 s Bross, Peter edt Gregersen, Niels edt Erscheint auch als Druck-Ausgabe 9781588290656 https://doi.org/10.1385/1592593941 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Protein Misfolding and Disease Principles and Protocols Life Sciences Biochemistry, general Life sciences Biochemistry Degeneration (DE-588)4132275-7 gnd Stoffwechselkrankheit (DE-588)4057700-4 gnd Altern (DE-588)4068596-2 gnd Proteinfaltung (DE-588)4324567-5 gnd |
| subject_GND | (DE-588)4132275-7 (DE-588)4057700-4 (DE-588)4068596-2 (DE-588)4324567-5 (DE-588)4143413-4 |
| title | Protein Misfolding and Disease Principles and Protocols |
| title_auth | Protein Misfolding and Disease Principles and Protocols |
| title_exact_search | Protein Misfolding and Disease Principles and Protocols |
| title_full | Protein Misfolding and Disease Principles and Protocols edited by Peter Bross, Niels Gregersen |
| title_fullStr | Protein Misfolding and Disease Principles and Protocols edited by Peter Bross, Niels Gregersen |
| title_full_unstemmed | Protein Misfolding and Disease Principles and Protocols edited by Peter Bross, Niels Gregersen |
| title_short | Protein Misfolding and Disease |
| title_sort | protein misfolding and disease principles and protocols |
| title_sub | Principles and Protocols |
| topic | Life Sciences Biochemistry, general Life sciences Biochemistry Degeneration (DE-588)4132275-7 gnd Stoffwechselkrankheit (DE-588)4057700-4 gnd Altern (DE-588)4068596-2 gnd Proteinfaltung (DE-588)4324567-5 gnd |
| topic_facet | Life Sciences Biochemistry, general Life sciences Biochemistry Degeneration Stoffwechselkrankheit Altern Proteinfaltung Aufsatzsammlung |
| url | https://doi.org/10.1385/1592593941 |
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