DNA Methylation Protocols:
Since methylation is now understood to be integral to DNA replication and transcription, with abnormalities frequently found to occur during tumorigenesis, the number of breakthrough techniques for methylation's study has sharply increased. In DNA Methylation Protocols, an internationally well-...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Springer New York
2002
|
| Schriftenreihe: | Methods in Molecular Biology™
200 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | Since methylation is now understood to be integral to DNA replication and transcription, with abnormalities frequently found to occur during tumorigenesis, the number of breakthrough techniques for methylation's study has sharply increased. In DNA Methylation Protocols, an internationally well-recognized panel of investigators offer a set of readily reproducible protocols for the analysis of DNA methylation and methylases. These powerful methods provide the tools necessary for studying methylation at both the global level and the level of sequence, and include many techniques for identifying genes that might be aberrantly methylated in cancer and aging. Additional methods cover genome-wide analysis of abnormal DNA methylation, and the isolation and measurement of demethylases and related proteins. Each technique is described by a hands-on master, and includes a concise summary of the basic theory, a complete materials list, step-by-step instructions for its successful execution, and helpful notes on avoiding pitfalls. Comprehensive and cutting-edge, DNA Methylation Protocols brings together not only the basic methods, but also the many exciting new techniques available today for the analysis of gene- and site-specific DNA methylation, and will prove invaluable to all researchers investigating replication, transcription, growth, differentiation, and carcinogenesis today |
| Beschreibung: | 1 Online-Ressource (X, 189 p) |
| ISBN: | 9781592591824 |
| DOI: | 10.1385/1592591825 |
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| 520 | |a Since methylation is now understood to be integral to DNA replication and transcription, with abnormalities frequently found to occur during tumorigenesis, the number of breakthrough techniques for methylation's study has sharply increased. In DNA Methylation Protocols, an internationally well-recognized panel of investigators offer a set of readily reproducible protocols for the analysis of DNA methylation and methylases. These powerful methods provide the tools necessary for studying methylation at both the global level and the level of sequence, and include many techniques for identifying genes that might be aberrantly methylated in cancer and aging. Additional methods cover genome-wide analysis of abnormal DNA methylation, and the isolation and measurement of demethylases and related proteins. Each technique is described by a hands-on master, and includes a concise summary of the basic theory, a complete materials list, step-by-step instructions for its successful execution, and helpful notes on avoiding pitfalls. Comprehensive and cutting-edge, DNA Methylation Protocols brings together not only the basic methods, but also the many exciting new techniques available today for the analysis of gene- and site-specific DNA methylation, and will prove invaluable to all researchers investigating replication, transcription, growth, differentiation, and carcinogenesis today | ||
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Datensatz im Suchindex
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| spelling | DNA Methylation Protocols edited by Ken I. Mills, Bernard H. Ramsahoye Totowa, NJ Springer New York 2002 1 Online-Ressource (X, 189 p) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology™ 200 Since methylation is now understood to be integral to DNA replication and transcription, with abnormalities frequently found to occur during tumorigenesis, the number of breakthrough techniques for methylation's study has sharply increased. In DNA Methylation Protocols, an internationally well-recognized panel of investigators offer a set of readily reproducible protocols for the analysis of DNA methylation and methylases. These powerful methods provide the tools necessary for studying methylation at both the global level and the level of sequence, and include many techniques for identifying genes that might be aberrantly methylated in cancer and aging. Additional methods cover genome-wide analysis of abnormal DNA methylation, and the isolation and measurement of demethylases and related proteins. Each technique is described by a hands-on master, and includes a concise summary of the basic theory, a complete materials list, step-by-step instructions for its successful execution, and helpful notes on avoiding pitfalls. Comprehensive and cutting-edge, DNA Methylation Protocols brings together not only the basic methods, but also the many exciting new techniques available today for the analysis of gene- and site-specific DNA methylation, and will prove invaluable to all researchers investigating replication, transcription, growth, differentiation, and carcinogenesis today Life Sciences Biochemistry, general Life sciences Biochemistry Methylierung (DE-588)4123751-1 gnd rswk-swf DNS-Methyltransferase (DE-588)4150344-2 gnd rswk-swf DNS (DE-588)4070512-2 gnd rswk-swf Labortechnik (DE-588)4123602-6 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content DNS-Methyltransferase (DE-588)4150344-2 s Labortechnik (DE-588)4123602-6 s DE-604 DNS (DE-588)4070512-2 s Methylierung (DE-588)4123751-1 s Mills, Ken I. edt Ramsahoye, Bernard H. edt Erscheint auch als Druck-Ausgabe 9780896036185 https://doi.org/10.1385/1592591825 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | DNA Methylation Protocols Life Sciences Biochemistry, general Life sciences Biochemistry Methylierung (DE-588)4123751-1 gnd DNS-Methyltransferase (DE-588)4150344-2 gnd DNS (DE-588)4070512-2 gnd Labortechnik (DE-588)4123602-6 gnd |
| subject_GND | (DE-588)4123751-1 (DE-588)4150344-2 (DE-588)4070512-2 (DE-588)4123602-6 (DE-588)4143413-4 |
| title | DNA Methylation Protocols |
| title_auth | DNA Methylation Protocols |
| title_exact_search | DNA Methylation Protocols |
| title_full | DNA Methylation Protocols edited by Ken I. Mills, Bernard H. Ramsahoye |
| title_fullStr | DNA Methylation Protocols edited by Ken I. Mills, Bernard H. Ramsahoye |
| title_full_unstemmed | DNA Methylation Protocols edited by Ken I. Mills, Bernard H. Ramsahoye |
| title_short | DNA Methylation Protocols |
| title_sort | dna methylation protocols |
| topic | Life Sciences Biochemistry, general Life sciences Biochemistry Methylierung (DE-588)4123751-1 gnd DNS-Methyltransferase (DE-588)4150344-2 gnd DNS (DE-588)4070512-2 gnd Labortechnik (DE-588)4123602-6 gnd |
| topic_facet | Life Sciences Biochemistry, general Life sciences Biochemistry Methylierung DNS-Methyltransferase DNS Labortechnik Aufsatzsammlung |
| url | https://doi.org/10.1385/1592591825 |
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