Capillary Electrophoresis of Nucleic Acids: Volume I: Introduction to the Capillary Electrophoresis of Nucleic Acids
The advent of capillary electrophoresis (CE) , with its power to separate and analyze very small amounts of DNA, has generated a host of DNA analytical procedures. In these novel and wide-ranging volumes of Capillary Electrophoresis of Nucleic Acids, an outstanding panel of hands-on experts and deve...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2001
|
| Schriftenreihe: | Methods in Molecular Biology
162 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | The advent of capillary electrophoresis (CE) , with its power to separate and analyze very small amounts of DNA, has generated a host of DNA analytical procedures. In these novel and wide-ranging volumes of Capillary Electrophoresis of Nucleic Acids, an outstanding panel of hands-on experts and developers of CE equipment describe in step-by-step fashion their best cutting-edge methods for the detection and analysis of DNA mutations and modifications, ranging from precise DNA loci to entire genomes of organisms. This first volume of the set, Introduction to the Capillary Electrophoresis of Nucleic Acids, covers the practical and theoretical considerations behind the use of capillary electrophoresis for the analysis of small oligonucleotides and modified nucleotides. Along with detailed instructions ensuring ready reproducibility, these protocols offer time-tested advice on instrumentation, signal detection, the capillary environment, and the integration of mass spectrometry with CE. Several chapters are devoted to the analysis of small therapeutic oligonucleotides, nucleosides, and ribonucleotides by CE. The companion volume, Practical Applications of Capillary Electrophoresis, addresses techniques for high-throughput analysis of DNA fragments using SNP detection, mutation detection, DNA sequencing methods, and DNA-ligand interactions. Comprehensive and up-to-date, the paired volumes of Capillary Electrophoresis of Nucleic Acids offer an authoritative guide with easy access to fast, versatile, reliable, and powerful technologies for all those basic and clinical investigators analyzing DNA variation today |
| Beschreibung: | 1 Online-Ressource (XVI, 484 p) |
| ISBN: | 9781592590551 |
| DOI: | 10.1385/1592590551 |
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| 520 | |a The advent of capillary electrophoresis (CE) , with its power to separate and analyze very small amounts of DNA, has generated a host of DNA analytical procedures. In these novel and wide-ranging volumes of Capillary Electrophoresis of Nucleic Acids, an outstanding panel of hands-on experts and developers of CE equipment describe in step-by-step fashion their best cutting-edge methods for the detection and analysis of DNA mutations and modifications, ranging from precise DNA loci to entire genomes of organisms. This first volume of the set, Introduction to the Capillary Electrophoresis of Nucleic Acids, covers the practical and theoretical considerations behind the use of capillary electrophoresis for the analysis of small oligonucleotides and modified nucleotides. Along with detailed instructions ensuring ready reproducibility, these protocols offer time-tested advice on instrumentation, signal detection, the capillary environment, and the integration of mass spectrometry with CE. Several chapters are devoted to the analysis of small therapeutic oligonucleotides, nucleosides, and ribonucleotides by CE. The companion volume, Practical Applications of Capillary Electrophoresis, addresses techniques for high-throughput analysis of DNA fragments using SNP detection, mutation detection, DNA sequencing methods, and DNA-ligand interactions. Comprehensive and up-to-date, the paired volumes of Capillary Electrophoresis of Nucleic Acids offer an authoritative guide with easy access to fast, versatile, reliable, and powerful technologies for all those basic and clinical investigators analyzing DNA variation today | ||
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| spelling | Capillary Electrophoresis of Nucleic Acids Volume I: Introduction to the Capillary Electrophoresis of Nucleic Acids edited by Keith R. Mitchelson, Jing Cheng Totowa, NJ Humana Press 2001 1 Online-Ressource (XVI, 484 p) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology 162 The advent of capillary electrophoresis (CE) , with its power to separate and analyze very small amounts of DNA, has generated a host of DNA analytical procedures. In these novel and wide-ranging volumes of Capillary Electrophoresis of Nucleic Acids, an outstanding panel of hands-on experts and developers of CE equipment describe in step-by-step fashion their best cutting-edge methods for the detection and analysis of DNA mutations and modifications, ranging from precise DNA loci to entire genomes of organisms. This first volume of the set, Introduction to the Capillary Electrophoresis of Nucleic Acids, covers the practical and theoretical considerations behind the use of capillary electrophoresis for the analysis of small oligonucleotides and modified nucleotides. Along with detailed instructions ensuring ready reproducibility, these protocols offer time-tested advice on instrumentation, signal detection, the capillary environment, and the integration of mass spectrometry with CE. Several chapters are devoted to the analysis of small therapeutic oligonucleotides, nucleosides, and ribonucleotides by CE. The companion volume, Practical Applications of Capillary Electrophoresis, addresses techniques for high-throughput analysis of DNA fragments using SNP detection, mutation detection, DNA sequencing methods, and DNA-ligand interactions. Comprehensive and up-to-date, the paired volumes of Capillary Electrophoresis of Nucleic Acids offer an authoritative guide with easy access to fast, versatile, reliable, and powerful technologies for all those basic and clinical investigators analyzing DNA variation today Life Sciences Biochemistry, general Life sciences Biochemistry Kapillarelektrophorese (DE-588)4290002-5 gnd rswk-swf DNS (DE-588)4070512-2 gnd rswk-swf Nucleinsäuren (DE-588)4172117-2 gnd rswk-swf DNS (DE-588)4070512-2 s Kapillarelektrophorese (DE-588)4290002-5 s DE-604 Nucleinsäuren (DE-588)4172117-2 s Mitchelson, Keith R. edt Cheng, Jing edt Erscheint auch als Druck-Ausgabe 9780896037793 https://doi.org/10.1385/1592590551 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Capillary Electrophoresis of Nucleic Acids Volume I: Introduction to the Capillary Electrophoresis of Nucleic Acids Life Sciences Biochemistry, general Life sciences Biochemistry Kapillarelektrophorese (DE-588)4290002-5 gnd DNS (DE-588)4070512-2 gnd Nucleinsäuren (DE-588)4172117-2 gnd |
| subject_GND | (DE-588)4290002-5 (DE-588)4070512-2 (DE-588)4172117-2 |
| title | Capillary Electrophoresis of Nucleic Acids Volume I: Introduction to the Capillary Electrophoresis of Nucleic Acids |
| title_auth | Capillary Electrophoresis of Nucleic Acids Volume I: Introduction to the Capillary Electrophoresis of Nucleic Acids |
| title_exact_search | Capillary Electrophoresis of Nucleic Acids Volume I: Introduction to the Capillary Electrophoresis of Nucleic Acids |
| title_full | Capillary Electrophoresis of Nucleic Acids Volume I: Introduction to the Capillary Electrophoresis of Nucleic Acids edited by Keith R. Mitchelson, Jing Cheng |
| title_fullStr | Capillary Electrophoresis of Nucleic Acids Volume I: Introduction to the Capillary Electrophoresis of Nucleic Acids edited by Keith R. Mitchelson, Jing Cheng |
| title_full_unstemmed | Capillary Electrophoresis of Nucleic Acids Volume I: Introduction to the Capillary Electrophoresis of Nucleic Acids edited by Keith R. Mitchelson, Jing Cheng |
| title_short | Capillary Electrophoresis of Nucleic Acids |
| title_sort | capillary electrophoresis of nucleic acids volume i introduction to the capillary electrophoresis of nucleic acids |
| title_sub | Volume I: Introduction to the Capillary Electrophoresis of Nucleic Acids |
| topic | Life Sciences Biochemistry, general Life sciences Biochemistry Kapillarelektrophorese (DE-588)4290002-5 gnd DNS (DE-588)4070512-2 gnd Nucleinsäuren (DE-588)4172117-2 gnd |
| topic_facet | Life Sciences Biochemistry, general Life sciences Biochemistry Kapillarelektrophorese DNS Nucleinsäuren |
| url | https://doi.org/10.1385/1592590551 |
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