Proteomics for Drug Discovery: Methods and Protocols
This book reflects the drug development community’s interest in proteomics methods by providing researchers with the necessary knowledge for the implementation of a number of basic experimental and bioinformatics protocols in the drug discovery research laboratory. The focus of the collection is on...
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Weitere Verfasser: | , , |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
New York, NY
Springer New York
2017
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Schriftenreihe: | Methods in Molecular Biology
1647 |
Schlagworte: | |
Online-Zugang: | UBR01 TUM01 Volltext |
Zusammenfassung: | This book reflects the drug development community’s interest in proteomics methods by providing researchers with the necessary knowledge for the implementation of a number of basic experimental and bioinformatics protocols in the drug discovery research laboratory. The focus of the collection is on select protocols and methodologies that address the analysis of post-translational modifications, targeted protein quantification, protein-protein, protein-lipid, or protein-ATP interactions, in silico lead identification, protein arrays, tissue and cell extract preparation, labeling, chemoproteomics, and drug efficacy assessment. Emphasis was placed not just on methods that describe large-scale protein analysis, but also on ones that are amenable to future implementation in a high-throughput format. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, Proteomics for Drug Discovery: Methods and Protocols aims to provide a deep knowledge of the fundamentals of disease biology as well the means that were developed for probing the complex biological milieu |
Beschreibung: | 1 Online-Ressource (XI, 302 p. 62 illus., 46 illus. in color) |
ISBN: | 9781493972012 |
DOI: | 10.1007/978-1-4939-7201-2 |
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Datensatz im Suchindex
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any_adam_object | |
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discipline | Medizin |
doi_str_mv | 10.1007/978-1-4939-7201-2 |
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isbn | 9781493972012 |
language | English |
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spelling | Proteomics for Drug Discovery Methods and Protocols edited by Iulia M. Lazar, Maria Kontoyianni, Alexandru C. Lazar New York, NY Springer New York 2017 1 Online-Ressource (XI, 302 p. 62 illus., 46 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology 1647 This book reflects the drug development community’s interest in proteomics methods by providing researchers with the necessary knowledge for the implementation of a number of basic experimental and bioinformatics protocols in the drug discovery research laboratory. The focus of the collection is on select protocols and methodologies that address the analysis of post-translational modifications, targeted protein quantification, protein-protein, protein-lipid, or protein-ATP interactions, in silico lead identification, protein arrays, tissue and cell extract preparation, labeling, chemoproteomics, and drug efficacy assessment. Emphasis was placed not just on methods that describe large-scale protein analysis, but also on ones that are amenable to future implementation in a high-throughput format. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, Proteomics for Drug Discovery: Methods and Protocols aims to provide a deep knowledge of the fundamentals of disease biology as well the means that were developed for probing the complex biological milieu Biomedicine Pharmacology/Toxicology Medicine Pharmacology Lazar, Iulia M. edt Kontoyianni, Maria edt Lazar, Alexandru C. edt Erscheint auch als Druck-Ausgabe 9781493972005 https://doi.org/10.1007/978-1-4939-7201-2 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Proteomics for Drug Discovery Methods and Protocols Biomedicine Pharmacology/Toxicology Medicine Pharmacology |
title | Proteomics for Drug Discovery Methods and Protocols |
title_auth | Proteomics for Drug Discovery Methods and Protocols |
title_exact_search | Proteomics for Drug Discovery Methods and Protocols |
title_full | Proteomics for Drug Discovery Methods and Protocols edited by Iulia M. Lazar, Maria Kontoyianni, Alexandru C. Lazar |
title_fullStr | Proteomics for Drug Discovery Methods and Protocols edited by Iulia M. Lazar, Maria Kontoyianni, Alexandru C. Lazar |
title_full_unstemmed | Proteomics for Drug Discovery Methods and Protocols edited by Iulia M. Lazar, Maria Kontoyianni, Alexandru C. Lazar |
title_short | Proteomics for Drug Discovery |
title_sort | proteomics for drug discovery methods and protocols |
title_sub | Methods and Protocols |
topic | Biomedicine Pharmacology/Toxicology Medicine Pharmacology |
topic_facet | Biomedicine Pharmacology/Toxicology Medicine Pharmacology |
url | https://doi.org/10.1007/978-1-4939-7201-2 |
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