Techniques to Investigate Mitochondrial Function in Neurons:
This volume describes a broad spectrum of experimental approaches for investigating structure, function, and transport of neuronal mitochondria in health and disease. Most of these approaches were only recently developed and range from electron tomography-based 3D reconstruction of mitochondrial cri...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer New York
2017
|
| Schriftenreihe: | Neuromethods
123 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | This volume describes a broad spectrum of experimental approaches for investigating structure, function, and transport of neuronal mitochondria in health and disease. Most of these approaches were only recently developed and range from electron tomography-based 3D reconstruction of mitochondrial cristae to patch clamp recording from mitochondria in intact neurons. The chapters in this book cover topics such as mitochondrial proteomics, fluorescence lifetime imaging, respirometry and mitophagy, as well as optical approaches based on the use of genetically engineered fluorescent sensors for monitoring synaptic ATP and axonal ROS generation, mitochondrial Ca2+ cycling and pH changes, and mitochondrial dynamics and axonal trafficking in live neurons. Each chapter also discusses difficulties, tips, tricks, and precautions to take. Neuromethods series style chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and comprehensive, Techniques to Investigate Mitochondrial Function in Neurons is a valuable and useful resource for a broad range of investigators interested in the function of neuronal mitochondria in health and disease states. |
| Beschreibung: | 1 Online-Ressource (XV, 344 p. 74 illus., 51 illus. in color) |
| ISBN: | 9781493968909 |
| DOI: | 10.1007/978-1-4939-6890-9 |
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Datensatz im Suchindex
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| dewey-full | 612.8 |
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| discipline | Biologie Medizin |
| doi_str_mv | 10.1007/978-1-4939-6890-9 |
| format | Electronic eBook |
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| indexdate | 2024-07-10T08:05:37Z |
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| isbn | 9781493968909 |
| language | English |
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| spelling | Techniques to Investigate Mitochondrial Function in Neurons edited by Stefan Strack, Yuriy M. Usachev New York, NY Springer New York 2017 1 Online-Ressource (XV, 344 p. 74 illus., 51 illus. in color) txt rdacontent c rdamedia cr rdacarrier Neuromethods 123 This volume describes a broad spectrum of experimental approaches for investigating structure, function, and transport of neuronal mitochondria in health and disease. Most of these approaches were only recently developed and range from electron tomography-based 3D reconstruction of mitochondrial cristae to patch clamp recording from mitochondria in intact neurons. The chapters in this book cover topics such as mitochondrial proteomics, fluorescence lifetime imaging, respirometry and mitophagy, as well as optical approaches based on the use of genetically engineered fluorescent sensors for monitoring synaptic ATP and axonal ROS generation, mitochondrial Ca2+ cycling and pH changes, and mitochondrial dynamics and axonal trafficking in live neurons. Each chapter also discusses difficulties, tips, tricks, and precautions to take. Neuromethods series style chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and comprehensive, Techniques to Investigate Mitochondrial Function in Neurons is a valuable and useful resource for a broad range of investigators interested in the function of neuronal mitochondria in health and disease states. Biomedicine Neurosciences Medicine Mitochondrium (DE-588)4124939-2 gnd rswk-swf Nervenzelle (DE-588)4041649-5 gnd rswk-swf Nervenzelle (DE-588)4041649-5 s Mitochondrium (DE-588)4124939-2 s b DE-604 Strack, Stefan edt Usachev, Yuriy M. edt Erscheint auch als Druck-Ausgabe 9781493968886 https://doi.org/10.1007/978-1-4939-6890-9 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Techniques to Investigate Mitochondrial Function in Neurons Biomedicine Neurosciences Medicine Mitochondrium (DE-588)4124939-2 gnd Nervenzelle (DE-588)4041649-5 gnd |
| subject_GND | (DE-588)4124939-2 (DE-588)4041649-5 |
| title | Techniques to Investigate Mitochondrial Function in Neurons |
| title_auth | Techniques to Investigate Mitochondrial Function in Neurons |
| title_exact_search | Techniques to Investigate Mitochondrial Function in Neurons |
| title_full | Techniques to Investigate Mitochondrial Function in Neurons edited by Stefan Strack, Yuriy M. Usachev |
| title_fullStr | Techniques to Investigate Mitochondrial Function in Neurons edited by Stefan Strack, Yuriy M. Usachev |
| title_full_unstemmed | Techniques to Investigate Mitochondrial Function in Neurons edited by Stefan Strack, Yuriy M. Usachev |
| title_short | Techniques to Investigate Mitochondrial Function in Neurons |
| title_sort | techniques to investigate mitochondrial function in neurons |
| topic | Biomedicine Neurosciences Medicine Mitochondrium (DE-588)4124939-2 gnd Nervenzelle (DE-588)4041649-5 gnd |
| topic_facet | Biomedicine Neurosciences Medicine Mitochondrium Nervenzelle |
| url | https://doi.org/10.1007/978-1-4939-6890-9 |
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