Mouse Models of Cancer: Methods and Protocols
This volume is essential for geneticists, molecular biologists, biochemists, and medical doctors interested in the use of mouse models in cancer research. Recent genome studies, together with refined genetic engineering techniques, have greatly increased the value of using mice for research on cance...
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Weitere Verfasser: | , |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
New York, NY
Springer New York
2015
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Schriftenreihe: | Methods in Molecular Biology
1267 |
Schlagworte: | |
Online-Zugang: | UBR01 TUM01 Volltext |
Zusammenfassung: | This volume is essential for geneticists, molecular biologists, biochemists, and medical doctors interested in the use of mouse models in cancer research. Recent genome studies, together with refined genetic engineering techniques, have greatly increased the value of using mice for research on cancer and other human disorders. The chapters of this book will support scientists in choosing the most suitable mouse models for their research questions. The book provides detailed methodological information for genetic or chemical induction of different types of cancer, histomorphometric cancer analysis, and in vivo imaging, as well as protocols to investigate oncogene addiction, immune surveillance, and hallmarks of cancer such as angiogenesis or metastasis. Four review-like articles provide background information on mouse technologies and histopathologic differences between mouse and human cancers. The mouse models described in individual chapters will fuel the understanding of cancer initiation, immune system roles, tumor angiogenesis, invasion, metastasis, and the relevance of molecular diversity observed among human cancers. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and resourceful, Mouse Models of Cancers: Methods and Protocols, is a valuable laboratory resource for all researchers, from the graduate level upwards, who study cancer and new possibilities for its treatment |
Beschreibung: | 1 Online-Ressource (XI, 463 p. 96 illus., 87 illus. in color) |
ISBN: | 9781493922970 |
DOI: | 10.1007/978-1-4939-2297-0 |
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Datensatz im Suchindex
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any_adam_object | |
author2 | Eferl, Robert Casanova, Emilio |
author2_role | edt edt |
author2_variant | r e re e c ec |
author_facet | Eferl, Robert Casanova, Emilio |
building | Verbundindex |
bvnumber | BV044952134 |
classification_rvk | XH 2512 |
collection | ZDB-2-PRO |
ctrlnum | (ZDB-2-PRO)978-1-4939-2297-0 (OCoLC)1036315828 (DE-599)BVBBV044952134 |
dewey-full | 614.5999 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 614 - Forensic medicine; incidence of disease |
dewey-raw | 614.5999 |
dewey-search | 614.5999 |
dewey-sort | 3614.5999 |
dewey-tens | 610 - Medicine and health |
discipline | Medizin |
doi_str_mv | 10.1007/978-1-4939-2297-0 |
format | Electronic eBook |
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spelling | Mouse Models of Cancer Methods and Protocols edited by Robert Eferl, Emilio Casanova New York, NY Springer New York 2015 1 Online-Ressource (XI, 463 p. 96 illus., 87 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology 1267 This volume is essential for geneticists, molecular biologists, biochemists, and medical doctors interested in the use of mouse models in cancer research. Recent genome studies, together with refined genetic engineering techniques, have greatly increased the value of using mice for research on cancer and other human disorders. The chapters of this book will support scientists in choosing the most suitable mouse models for their research questions. The book provides detailed methodological information for genetic or chemical induction of different types of cancer, histomorphometric cancer analysis, and in vivo imaging, as well as protocols to investigate oncogene addiction, immune surveillance, and hallmarks of cancer such as angiogenesis or metastasis. Four review-like articles provide background information on mouse technologies and histopathologic differences between mouse and human cancers. The mouse models described in individual chapters will fuel the understanding of cancer initiation, immune system roles, tumor angiogenesis, invasion, metastasis, and the relevance of molecular diversity observed among human cancers. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and resourceful, Mouse Models of Cancers: Methods and Protocols, is a valuable laboratory resource for all researchers, from the graduate level upwards, who study cancer and new possibilities for its treatment Biomedicine Cancer Research Oncology Animal Models Medicine Cancer research Animal models in research Krebs Medizin (DE-588)4073781-0 gnd rswk-swf Tiermodell (DE-588)4140660-6 gnd rswk-swf Pathophysiologie (DE-588)4044898-8 gnd rswk-swf Maus (DE-588)4169148-9 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Maus (DE-588)4169148-9 s Tiermodell (DE-588)4140660-6 s Krebs Medizin (DE-588)4073781-0 s Pathophysiologie (DE-588)4044898-8 s 2\p DE-604 Eferl, Robert edt Casanova, Emilio edt Erscheint auch als Druck-Ausgabe 9781493922963 https://doi.org/10.1007/978-1-4939-2297-0 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
spellingShingle | Mouse Models of Cancer Methods and Protocols Biomedicine Cancer Research Oncology Animal Models Medicine Cancer research Animal models in research Krebs Medizin (DE-588)4073781-0 gnd Tiermodell (DE-588)4140660-6 gnd Pathophysiologie (DE-588)4044898-8 gnd Maus (DE-588)4169148-9 gnd |
subject_GND | (DE-588)4073781-0 (DE-588)4140660-6 (DE-588)4044898-8 (DE-588)4169148-9 (DE-588)4143413-4 |
title | Mouse Models of Cancer Methods and Protocols |
title_auth | Mouse Models of Cancer Methods and Protocols |
title_exact_search | Mouse Models of Cancer Methods and Protocols |
title_full | Mouse Models of Cancer Methods and Protocols edited by Robert Eferl, Emilio Casanova |
title_fullStr | Mouse Models of Cancer Methods and Protocols edited by Robert Eferl, Emilio Casanova |
title_full_unstemmed | Mouse Models of Cancer Methods and Protocols edited by Robert Eferl, Emilio Casanova |
title_short | Mouse Models of Cancer |
title_sort | mouse models of cancer methods and protocols |
title_sub | Methods and Protocols |
topic | Biomedicine Cancer Research Oncology Animal Models Medicine Cancer research Animal models in research Krebs Medizin (DE-588)4073781-0 gnd Tiermodell (DE-588)4140660-6 gnd Pathophysiologie (DE-588)4044898-8 gnd Maus (DE-588)4169148-9 gnd |
topic_facet | Biomedicine Cancer Research Oncology Animal Models Medicine Cancer research Animal models in research Krebs Medizin Tiermodell Pathophysiologie Maus Aufsatzsammlung |
url | https://doi.org/10.1007/978-1-4939-2297-0 |
work_keys_str_mv | AT eferlrobert mousemodelsofcancermethodsandprotocols AT casanovaemilio mousemodelsofcancermethodsandprotocols |