LC-MS in Drug Analysis: Methods and Protocols
Liquid-Chromatography-Mass-Spectrometry procedures have been shown to be successful when applied to drug development and analysis. LC-MS in Drug Analysis: Methods and Protocols provides detailed LC-MS/MS procedures for the analysis of several compounds of clinical significance. The first chapters p...
Gespeichert in:
Weitere Verfasser: | , |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Totowa, NJ
Humana Press
2012
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Schriftenreihe: | Methods in Molecular Biology, Methods and Protocols
902 |
Schlagworte: | |
Online-Zugang: | UBR01 TUM01 URL des Erstveröffentlichers |
Zusammenfassung: | Liquid-Chromatography-Mass-Spectrometry procedures have been shown to be successful when applied to drug development and analysis. LC-MS in Drug Analysis: Methods and Protocols provides detailed LC-MS/MS procedures for the analysis of several compounds of clinical significance. The first chapters provide the reader with an overview of mass spectroscopy, its place in clinical practice, its application of MS to TDM and toxicology, and the merits of LC-MS(/MS) and new sample preparation techniques. The following chapters discuss different approaches to screening for drugs of abuse and for general unknowns, as well as targeted measurement of specific analytes or classes of analytes including abused drugs, toxic compounds, and therapeutic agents. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, LC-MS in Drug Analysis: Methods and Protocols seeks to serve both professionals and novices with its well-honed methodologies |
Beschreibung: | 1 Online-Ressource (X, 224 p. 27 illus., 5 illus. in color) |
ISBN: | 9781617799341 |
DOI: | 10.1007/978-1-61779-934-1 |
Internformat
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520 | |a Liquid-Chromatography-Mass-Spectrometry procedures have been shown to be successful when applied to drug development and analysis. LC-MS in Drug Analysis: Methods and Protocols provides detailed LC-MS/MS procedures for the analysis of several compounds of clinical significance. The first chapters provide the reader with an overview of mass spectroscopy, its place in clinical practice, its application of MS to TDM and toxicology, and the merits of LC-MS(/MS) and new sample preparation techniques. The following chapters discuss different approaches to screening for drugs of abuse and for general unknowns, as well as targeted measurement of specific analytes or classes of analytes including abused drugs, toxic compounds, and therapeutic agents. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, LC-MS in Drug Analysis: Methods and Protocols seeks to serve both professionals and novices with its well-honed methodologies | ||
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Datensatz im Suchindex
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any_adam_object | |
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dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 615 - Pharmacology and therapeutics |
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dewey-search | 615 |
dewey-sort | 3615 |
dewey-tens | 610 - Medicine and health |
discipline | Medizin |
doi_str_mv | 10.1007/978-1-61779-934-1 |
format | Electronic eBook |
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isbn | 9781617799341 |
language | English |
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spelling | LC-MS in Drug Analysis Methods and Protocols edited by Loralie J. Langman, Christine L. H. Snozek Totowa, NJ Humana Press 2012 1 Online-Ressource (X, 224 p. 27 illus., 5 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology, Methods and Protocols 902 Liquid-Chromatography-Mass-Spectrometry procedures have been shown to be successful when applied to drug development and analysis. LC-MS in Drug Analysis: Methods and Protocols provides detailed LC-MS/MS procedures for the analysis of several compounds of clinical significance. The first chapters provide the reader with an overview of mass spectroscopy, its place in clinical practice, its application of MS to TDM and toxicology, and the merits of LC-MS(/MS) and new sample preparation techniques. The following chapters discuss different approaches to screening for drugs of abuse and for general unknowns, as well as targeted measurement of specific analytes or classes of analytes including abused drugs, toxic compounds, and therapeutic agents. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, LC-MS in Drug Analysis: Methods and Protocols seeks to serve both professionals and novices with its well-honed methodologies Biomedicine Pharmacology/Toxicology Spectroscopy/Spectrometry Medicine Pharmacology Spectroscopy Langman, Loralie J. edt Snozek, Christine L. H. edt Erscheint auch als Druck-Ausgabe 9781617799334 https://doi.org/10.1007/978-1-61779-934-1 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | LC-MS in Drug Analysis Methods and Protocols Biomedicine Pharmacology/Toxicology Spectroscopy/Spectrometry Medicine Pharmacology Spectroscopy |
title | LC-MS in Drug Analysis Methods and Protocols |
title_auth | LC-MS in Drug Analysis Methods and Protocols |
title_exact_search | LC-MS in Drug Analysis Methods and Protocols |
title_full | LC-MS in Drug Analysis Methods and Protocols edited by Loralie J. Langman, Christine L. H. Snozek |
title_fullStr | LC-MS in Drug Analysis Methods and Protocols edited by Loralie J. Langman, Christine L. H. Snozek |
title_full_unstemmed | LC-MS in Drug Analysis Methods and Protocols edited by Loralie J. Langman, Christine L. H. Snozek |
title_short | LC-MS in Drug Analysis |
title_sort | lc ms in drug analysis methods and protocols |
title_sub | Methods and Protocols |
topic | Biomedicine Pharmacology/Toxicology Spectroscopy/Spectrometry Medicine Pharmacology Spectroscopy |
topic_facet | Biomedicine Pharmacology/Toxicology Spectroscopy/Spectrometry Medicine Pharmacology Spectroscopy |
url | https://doi.org/10.1007/978-1-61779-934-1 |
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