Protein Microarray for Disease Analysis: Methods and Protocols
Protein microarrays have been used for a wide variety of important tasks, such as identifying protein-protein interactions, discovering disease biomarkers, identifying DNA-binding specificity by protein variants, and for characterization of the humoral immune response. In Protein Microarray for Dis...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2011
|
| Schriftenreihe: | Methods in Molecular Biology, Methods and Protocols
723 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | Protein microarrays have been used for a wide variety of important tasks, such as identifying protein-protein interactions, discovering disease biomarkers, identifying DNA-binding specificity by protein variants, and for characterization of the humoral immune response. In Protein Microarray for Disease Analysis: Methods and Protocols, expert researchers provide concise descriptions of the methodologies currently used to fabricate microarrays for the comprehensive analysis of proteins or responses to proteins that can be used to dissect human disease. These methodologies are the toolbox for revolutionizing drug development and cell-level biochemical understanding of human disease processes. Beginning with a section on protein-detecting analytical microarrays, the volume continues with sections covering antigen microarrays for immunoprofiling, protein function microarrays, the validation of candidate targets, proteomic libraries, as well as signal detection strategies and data analysis techniques. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Practical and cutting-edge, Protein Microarray for Disease Analysis: Methods and Protocols serves as a solid framework to aid scientists in understanding how protein microarray technology is presently developing and how it can be applied to transform our analysis of human disease |
| Beschreibung: | 1 Online-Ressource (XIII, 373 p) |
| ISBN: | 9781617790430 |
| DOI: | 10.1007/978-1-61779-043-0 |
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| spelling | Protein Microarray for Disease Analysis Methods and Protocols edited by Catherine J. Wu Totowa, NJ Humana Press 2011 1 Online-Ressource (XIII, 373 p) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology, Methods and Protocols 723 Protein microarrays have been used for a wide variety of important tasks, such as identifying protein-protein interactions, discovering disease biomarkers, identifying DNA-binding specificity by protein variants, and for characterization of the humoral immune response. In Protein Microarray for Disease Analysis: Methods and Protocols, expert researchers provide concise descriptions of the methodologies currently used to fabricate microarrays for the comprehensive analysis of proteins or responses to proteins that can be used to dissect human disease. These methodologies are the toolbox for revolutionizing drug development and cell-level biochemical understanding of human disease processes. Beginning with a section on protein-detecting analytical microarrays, the volume continues with sections covering antigen microarrays for immunoprofiling, protein function microarrays, the validation of candidate targets, proteomic libraries, as well as signal detection strategies and data analysis techniques. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Practical and cutting-edge, Protein Microarray for Disease Analysis: Methods and Protocols serves as a solid framework to aid scientists in understanding how protein microarray technology is presently developing and how it can be applied to transform our analysis of human disease Life Sciences Protein Science Microarrays Life sciences Proteins Microarray (DE-588)4544227-7 gnd rswk-swf Diagnostik (DE-588)4113303-1 gnd rswk-swf Proteine (DE-588)4076388-2 gnd rswk-swf Proteine (DE-588)4076388-2 s Microarray (DE-588)4544227-7 s Diagnostik (DE-588)4113303-1 s 1\p DE-604 Wu, Catherine J. edt Erscheint auch als Druck-Ausgabe 9781617790423 https://doi.org/10.1007/978-1-61779-043-0 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Protein Microarray for Disease Analysis Methods and Protocols Life Sciences Protein Science Microarrays Life sciences Proteins Microarray (DE-588)4544227-7 gnd Diagnostik (DE-588)4113303-1 gnd Proteine (DE-588)4076388-2 gnd |
| subject_GND | (DE-588)4544227-7 (DE-588)4113303-1 (DE-588)4076388-2 |
| title | Protein Microarray for Disease Analysis Methods and Protocols |
| title_auth | Protein Microarray for Disease Analysis Methods and Protocols |
| title_exact_search | Protein Microarray for Disease Analysis Methods and Protocols |
| title_full | Protein Microarray for Disease Analysis Methods and Protocols edited by Catherine J. Wu |
| title_fullStr | Protein Microarray for Disease Analysis Methods and Protocols edited by Catherine J. Wu |
| title_full_unstemmed | Protein Microarray for Disease Analysis Methods and Protocols edited by Catherine J. Wu |
| title_short | Protein Microarray for Disease Analysis |
| title_sort | protein microarray for disease analysis methods and protocols |
| title_sub | Methods and Protocols |
| topic | Life Sciences Protein Science Microarrays Life sciences Proteins Microarray (DE-588)4544227-7 gnd Diagnostik (DE-588)4113303-1 gnd Proteine (DE-588)4076388-2 gnd |
| topic_facet | Life Sciences Protein Science Microarrays Life sciences Proteins Microarray Diagnostik Proteine |
| url | https://doi.org/10.1007/978-1-61779-043-0 |
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