Mouse Models for Drug Discovery: Methods and Protocols
As the drug discovery process shifts more and more toward specifically targeting pathways and molecules, model systems continue to increase in importance, and the mouse, with its versatility, ease of use, and remarkable similarity to the human genome, has clearly risen to the forefront of animal mod...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2010
|
| Schriftenreihe: | Methods in Molecular Biology, Methods and Protocols
602 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 URL des Erstveröffentlichers |
| Zusammenfassung: | As the drug discovery process shifts more and more toward specifically targeting pathways and molecules, model systems continue to increase in importance, and the mouse, with its versatility, ease of use, and remarkable similarity to the human genome, has clearly risen to the forefront of animal model studies. In Mouse Models for Drug Discovery: Methods and Protocols, experts in the field present some background for those less familiar with mice as experimental model platforms as well as a collection of techniques involving general methods as well as specific disease topics such as type 1 and 2 diabetes, cardiovascular disease, arthritis, skin disorders, cancer, the use of behavioral models for depression and anxiety, neurodegenerative diseases, neuromuscular diseases, and infectious diseases. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easy-to-use, Mouse Models for Drug Discovery: Methods and Protocols will stimulate those not familiar with the power of the mouse and its potential for the drug discovery process, and it will encourage the development of new models and new ways to utilize existing models in order to further the use of this dynamic animal in this vital field |
| Beschreibung: | 1 Online-Ressource (XII, 421 p) |
| ISBN: | 9781607610588 |
| DOI: | 10.1007/978-1-60761-058-8 |
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| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
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| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.1007/978-1-60761-058-8 |
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| spelling | Mouse Models for Drug Discovery Methods and Protocols edited by Gabriele Proetzel, Michael V. Wiles Totowa, NJ Humana Press 2010 1 Online-Ressource (XII, 421 p) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology, Methods and Protocols 602 As the drug discovery process shifts more and more toward specifically targeting pathways and molecules, model systems continue to increase in importance, and the mouse, with its versatility, ease of use, and remarkable similarity to the human genome, has clearly risen to the forefront of animal model studies. In Mouse Models for Drug Discovery: Methods and Protocols, experts in the field present some background for those less familiar with mice as experimental model platforms as well as a collection of techniques involving general methods as well as specific disease topics such as type 1 and 2 diabetes, cardiovascular disease, arthritis, skin disorders, cancer, the use of behavioral models for depression and anxiety, neurodegenerative diseases, neuromuscular diseases, and infectious diseases. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easy-to-use, Mouse Models for Drug Discovery: Methods and Protocols will stimulate those not familiar with the power of the mouse and its potential for the drug discovery process, and it will encourage the development of new models and new ways to utilize existing models in order to further the use of this dynamic animal in this vital field Biomedicine Pharmacology/Toxicology Laboratory Medicine Zoology Animal Models Medicine Laboratory medicine Pharmacology Animal models in research Proetzel, Gabriele edt Wiles, Michael V. edt Erscheint auch als Druck-Ausgabe 9781607610571 https://doi.org/10.1007/978-1-60761-058-8 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Mouse Models for Drug Discovery Methods and Protocols Biomedicine Pharmacology/Toxicology Laboratory Medicine Zoology Animal Models Medicine Laboratory medicine Pharmacology Animal models in research |
| title | Mouse Models for Drug Discovery Methods and Protocols |
| title_auth | Mouse Models for Drug Discovery Methods and Protocols |
| title_exact_search | Mouse Models for Drug Discovery Methods and Protocols |
| title_full | Mouse Models for Drug Discovery Methods and Protocols edited by Gabriele Proetzel, Michael V. Wiles |
| title_fullStr | Mouse Models for Drug Discovery Methods and Protocols edited by Gabriele Proetzel, Michael V. Wiles |
| title_full_unstemmed | Mouse Models for Drug Discovery Methods and Protocols edited by Gabriele Proetzel, Michael V. Wiles |
| title_short | Mouse Models for Drug Discovery |
| title_sort | mouse models for drug discovery methods and protocols |
| title_sub | Methods and Protocols |
| topic | Biomedicine Pharmacology/Toxicology Laboratory Medicine Zoology Animal Models Medicine Laboratory medicine Pharmacology Animal models in research |
| topic_facet | Biomedicine Pharmacology/Toxicology Laboratory Medicine Zoology Animal Models Medicine Laboratory medicine Pharmacology Animal models in research |
| url | https://doi.org/10.1007/978-1-60761-058-8 |
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