Therapeutic Applications of RNAi: Methods and Protocols
The phenomenon of RNA interference has rapidly moved from groundbreaking scientific discovery to promising therapeutic approach. However, even as RNAi-based drugs enter the clinic, significant challenges remain, particulary in the area of delivery. Therapeutic Applications of RNAi provides detailed...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2009
|
| Schriftenreihe: | Methods in Molecular Biology™, Methods and Protocols
555 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | The phenomenon of RNA interference has rapidly moved from groundbreaking scientific discovery to promising therapeutic approach. However, even as RNAi-based drugs enter the clinic, significant challenges remain, particulary in the area of delivery. Therapeutic Applications of RNAi provides detailed protocols in key areas of current focus, including testing of delivery vehicles, identification of appropriate model systems, and evaluation of the effects of RNAi in vivo. Produced by a team of internationally renowned authors, the volume describes the therapeutic applications of RNAi and potential pitfalls in oncology, viral infections and CNS disease, using a variety of delivery methods, including liposomes, peptide-based nanoparticles, polycationic polymers, and viral vehicles. Written in the highly successful Methods in Molecular Biology™ series format, the chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Therapeutic Applications of RNAi is an ideal guide for scientists attempting to solve the numerous challenges in this field and revolutionize the treatment of disease |
| Beschreibung: | 1 Online-Ressource (X, 148 p. 18 illus., 6 illus. in color) |
| ISBN: | 9781603272957 |
| DOI: | 10.1007/978-1-60327-295-7 |
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| spelling | Therapeutic Applications of RNAi Methods and Protocols edited by Cristina M. Rondinone, John F. Reidhaar-Olson Totowa, NJ Humana Press 2009 1 Online-Ressource (X, 148 p. 18 illus., 6 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology™, Methods and Protocols 555 The phenomenon of RNA interference has rapidly moved from groundbreaking scientific discovery to promising therapeutic approach. However, even as RNAi-based drugs enter the clinic, significant challenges remain, particulary in the area of delivery. Therapeutic Applications of RNAi provides detailed protocols in key areas of current focus, including testing of delivery vehicles, identification of appropriate model systems, and evaluation of the effects of RNAi in vivo. Produced by a team of internationally renowned authors, the volume describes the therapeutic applications of RNAi and potential pitfalls in oncology, viral infections and CNS disease, using a variety of delivery methods, including liposomes, peptide-based nanoparticles, polycationic polymers, and viral vehicles. Written in the highly successful Methods in Molecular Biology™ series format, the chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Therapeutic Applications of RNAi is an ideal guide for scientists attempting to solve the numerous challenges in this field and revolutionize the treatment of disease Biomedicine Pharmacology/Toxicology Biochemical Engineering Medicine Pharmacology Biochemical engineering RNS-Interferenz (DE-588)4802706-6 gnd rswk-swf Geninaktivierung (DE-588)4820638-6 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content RNS-Interferenz (DE-588)4802706-6 s Geninaktivierung (DE-588)4820638-6 s 2\p DE-604 Rondinone, Cristina M. edt Reidhaar-Olson, John F. edt Erscheint auch als Druck-Ausgabe 9781603272940 https://doi.org/10.1007/978-1-60327-295-7 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Therapeutic Applications of RNAi Methods and Protocols Biomedicine Pharmacology/Toxicology Biochemical Engineering Medicine Pharmacology Biochemical engineering RNS-Interferenz (DE-588)4802706-6 gnd Geninaktivierung (DE-588)4820638-6 gnd |
| subject_GND | (DE-588)4802706-6 (DE-588)4820638-6 (DE-588)4143413-4 |
| title | Therapeutic Applications of RNAi Methods and Protocols |
| title_auth | Therapeutic Applications of RNAi Methods and Protocols |
| title_exact_search | Therapeutic Applications of RNAi Methods and Protocols |
| title_full | Therapeutic Applications of RNAi Methods and Protocols edited by Cristina M. Rondinone, John F. Reidhaar-Olson |
| title_fullStr | Therapeutic Applications of RNAi Methods and Protocols edited by Cristina M. Rondinone, John F. Reidhaar-Olson |
| title_full_unstemmed | Therapeutic Applications of RNAi Methods and Protocols edited by Cristina M. Rondinone, John F. Reidhaar-Olson |
| title_short | Therapeutic Applications of RNAi |
| title_sort | therapeutic applications of rnai methods and protocols |
| title_sub | Methods and Protocols |
| topic | Biomedicine Pharmacology/Toxicology Biochemical Engineering Medicine Pharmacology Biochemical engineering RNS-Interferenz (DE-588)4802706-6 gnd Geninaktivierung (DE-588)4820638-6 gnd |
| topic_facet | Biomedicine Pharmacology/Toxicology Biochemical Engineering Medicine Pharmacology Biochemical engineering RNS-Interferenz Geninaktivierung Aufsatzsammlung |
| url | https://doi.org/10.1007/978-1-60327-295-7 |
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