DNA Vaccines: Methods and Protocols
In the early 1990s, almost 200 yr after Edward Jenner demonstrated the effectiveness of the smallpox vaccine, a new paradigm for vaccination emerged. The conventional method of vaccination required delivery of whole pathogens or structural subunits, but in this new approach, DNA or genetic informati...
Gespeichert in:
| Weitere Verfasser: | , , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2006
|
| Ausgabe: | Second Edition |
| Schriftenreihe: | Methods in Molecular Medicine™
127 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | In the early 1990s, almost 200 yr after Edward Jenner demonstrated the effectiveness of the smallpox vaccine, a new paradigm for vaccination emerged. The conventional method of vaccination required delivery of whole pathogens or structural subunits, but in this new approach, DNA or genetic information was administered to elicit an immunological response. Once it was observed that plasmid DNA delivered in vivo led to production of an encoded transgene (1), two ground-breaking studies demonstrated that immunological responses could be generated against antigenic transgenes via plasmid DNA delivered by DNA vaccination (as this approach is called) (2,3). The appe- ance of this new vaccination strategy coincided with advances in molecular biology, which provided new tools to study and manipulate the basic elements of an organism’s genome and also could also be applied to the design and production of DNA vaccines. DNA Vaccines is a major updated and enhancement of the first edition. It reviews state-of-the-art methods in DNA vaccine technology, with chapters describing DNA vaccine design, delivery systems, adjuvants, current appli- tions, methods of production, and quality control. Consistent with the approach of the Methods in Molecular Medicine series, these chapters contain detailed practical procedures on the latest DNA vaccine technology. The enthusiasm for DNA vaccine technology is made clear by the number of research studies published on this topic since the mid-1990s |
| Beschreibung: | 1 Online-Ressource (XVI, 384 p. 61 illus) |
| ISBN: | 9781597451680 |
| DOI: | 10.1385/1597451681 |
Internformat
MARC
| LEADER | 00000nmm a2200000zcb4500 | ||
|---|---|---|---|
| 001 | BV044951933 | ||
| 003 | DE-604 | ||
| 005 | 20180829 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 180517s2006 |||| o||u| ||||||eng d | ||
| 020 | |a 9781597451680 |9 978-1-59745-168-0 | ||
| 024 | 7 | |a 10.1385/1597451681 |2 doi | |
| 035 | |a (ZDB-2-PRO)978-1-59745-168-0 | ||
| 035 | |a (OCoLC)850742911 | ||
| 035 | |a (DE-599)BVBBV044951933 | ||
| 040 | |a DE-604 |b ger |e rda | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-355 |a DE-91 | ||
| 050 | 0 | |a QR189.5.D53 | |
| 082 | 0 | |a 616.079 |2 23 | |
| 082 | 0 | |a 615/.372 | |
| 084 | |a XD 3300 |0 (DE-625)152554:12905 |2 rvk | ||
| 245 | 1 | 0 | |a DNA Vaccines |b Methods and Protocols |c edited by W. Mark Saltzman, Hong Shen, Janet L. Brandsma |
| 250 | |a Second Edition | ||
| 264 | 1 | |a Totowa, NJ |b Humana Press |c 2006 | |
| 300 | |a 1 Online-Ressource (XVI, 384 p. 61 illus) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 490 | 0 | |a Methods in Molecular Medicine™ |v 127 | |
| 520 | |a In the early 1990s, almost 200 yr after Edward Jenner demonstrated the effectiveness of the smallpox vaccine, a new paradigm for vaccination emerged. The conventional method of vaccination required delivery of whole pathogens or structural subunits, but in this new approach, DNA or genetic information was administered to elicit an immunological response. Once it was observed that plasmid DNA delivered in vivo led to production of an encoded transgene (1), two ground-breaking studies demonstrated that immunological responses could be generated against antigenic transgenes via plasmid DNA delivered by DNA vaccination (as this approach is called) (2,3). The appe- ance of this new vaccination strategy coincided with advances in molecular biology, which provided new tools to study and manipulate the basic elements of an organism’s genome and also could also be applied to the design and production of DNA vaccines. DNA Vaccines is a major updated and enhancement of the first edition. It reviews state-of-the-art methods in DNA vaccine technology, with chapters describing DNA vaccine design, delivery systems, adjuvants, current appli- tions, methods of production, and quality control. Consistent with the approach of the Methods in Molecular Medicine series, these chapters contain detailed practical procedures on the latest DNA vaccine technology. The enthusiasm for DNA vaccine technology is made clear by the number of research studies published on this topic since the mid-1990s | ||
| 650 | 4 | |a Biomedicine | |
| 650 | 4 | |a Immunology | |
| 650 | 4 | |a Medicine | |
| 650 | 4 | |a Immunology | |
| 650 | 0 | 7 | |a DNS |0 (DE-588)4070512-2 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Impfstoff |0 (DE-588)4026655-2 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a DNS |0 (DE-588)4070512-2 |D s |
| 689 | 0 | 1 | |a Impfstoff |0 (DE-588)4026655-2 |D s |
| 689 | 0 | |C b |5 DE-604 | |
| 700 | 1 | |a Saltzman, W. Mark |4 edt | |
| 700 | 1 | |a Shen, Hong |4 edt | |
| 700 | 1 | |a Brandsma, Janet L. |4 edt | |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9781588294845 |
| 856 | 4 | 0 | |u https://doi.org/10.1385/1597451681 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
| 912 | |a ZDB-2-PRO | ||
| 999 | |a oai:aleph.bib-bvb.de:BVB01-030344689 | ||
| 966 | e | |u https://doi.org/10.1385/1597451681 |l UBR01 |p ZDB-2-PRO |x Verlag |3 Volltext | |
| 966 | e | |u https://doi.org/10.1385/1597451681 |l TUM01 |p ZDB-2-PRO |x Verlag |3 Volltext | |
Datensatz im Suchindex
| _version_ | 1804178541178257408 |
|---|---|
| any_adam_object | |
| author2 | Saltzman, W. Mark Shen, Hong Brandsma, Janet L. |
| author2_role | edt edt edt |
| author2_variant | w m s wm wms h s hs j l b jl jlb |
| author_facet | Saltzman, W. Mark Shen, Hong Brandsma, Janet L. |
| building | Verbundindex |
| bvnumber | BV044951933 |
| callnumber-first | Q - Science |
| callnumber-label | QR189 |
| callnumber-raw | QR189.5.D53 |
| callnumber-search | QR189.5.D53 |
| callnumber-sort | QR 3189.5 D53 |
| callnumber-subject | QR - Microbiology |
| classification_rvk | XD 3300 |
| collection | ZDB-2-PRO |
| ctrlnum | (ZDB-2-PRO)978-1-59745-168-0 (OCoLC)850742911 (DE-599)BVBBV044951933 |
| dewey-full | 616.079 615/.372 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases 615 - Pharmacology and therapeutics |
| dewey-raw | 616.079 615/.372 |
| dewey-search | 616.079 615/.372 |
| dewey-sort | 3616.079 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.1385/1597451681 |
| edition | Second Edition |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03368nmm a2200553zcb4500</leader><controlfield tag="001">BV044951933</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20180829 </controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">180517s2006 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781597451680</subfield><subfield code="9">978-1-59745-168-0</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1385/1597451681</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-2-PRO)978-1-59745-168-0</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)850742911</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV044951933</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield><subfield code="a">DE-91</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">QR189.5.D53</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">616.079</subfield><subfield code="2">23</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">615/.372</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">XD 3300</subfield><subfield code="0">(DE-625)152554:12905</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">DNA Vaccines</subfield><subfield code="b">Methods and Protocols</subfield><subfield code="c">edited by W. Mark Saltzman, Hong Shen, Janet L. Brandsma</subfield></datafield><datafield tag="250" ind1=" " ind2=" "><subfield code="a">Second Edition</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Totowa, NJ</subfield><subfield code="b">Humana Press</subfield><subfield code="c">2006</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (XVI, 384 p. 61 illus)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Methods in Molecular Medicine™</subfield><subfield code="v">127</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">In the early 1990s, almost 200 yr after Edward Jenner demonstrated the effectiveness of the smallpox vaccine, a new paradigm for vaccination emerged. The conventional method of vaccination required delivery of whole pathogens or structural subunits, but in this new approach, DNA or genetic information was administered to elicit an immunological response. Once it was observed that plasmid DNA delivered in vivo led to production of an encoded transgene (1), two ground-breaking studies demonstrated that immunological responses could be generated against antigenic transgenes via plasmid DNA delivered by DNA vaccination (as this approach is called) (2,3). The appe- ance of this new vaccination strategy coincided with advances in molecular biology, which provided new tools to study and manipulate the basic elements of an organism’s genome and also could also be applied to the design and production of DNA vaccines. DNA Vaccines is a major updated and enhancement of the first edition. It reviews state-of-the-art methods in DNA vaccine technology, with chapters describing DNA vaccine design, delivery systems, adjuvants, current appli- tions, methods of production, and quality control. Consistent with the approach of the Methods in Molecular Medicine series, these chapters contain detailed practical procedures on the latest DNA vaccine technology. The enthusiasm for DNA vaccine technology is made clear by the number of research studies published on this topic since the mid-1990s</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Biomedicine</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Immunology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Medicine</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Immunology</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">DNS</subfield><subfield code="0">(DE-588)4070512-2</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Impfstoff</subfield><subfield code="0">(DE-588)4026655-2</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">DNS</subfield><subfield code="0">(DE-588)4070512-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Impfstoff</subfield><subfield code="0">(DE-588)4026655-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="C">b</subfield><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Saltzman, W. Mark</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Shen, Hong</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Brandsma, Janet L.</subfield><subfield code="4">edt</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9781588294845</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1385/1597451681</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-2-PRO</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-030344689</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1385/1597451681</subfield><subfield code="l">UBR01</subfield><subfield code="p">ZDB-2-PRO</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1385/1597451681</subfield><subfield code="l">TUM01</subfield><subfield code="p">ZDB-2-PRO</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| id | DE-604.BV044951933 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:05:36Z |
| institution | BVB |
| isbn | 9781597451680 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-030344689 |
| oclc_num | 850742911 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-91 DE-BY-TUM |
| owner_facet | DE-355 DE-BY-UBR DE-91 DE-BY-TUM |
| physical | 1 Online-Ressource (XVI, 384 p. 61 illus) |
| psigel | ZDB-2-PRO |
| publishDate | 2006 |
| publishDateSearch | 2006 |
| publishDateSort | 2006 |
| publisher | Humana Press |
| record_format | marc |
| series2 | Methods in Molecular Medicine™ |
| spelling | DNA Vaccines Methods and Protocols edited by W. Mark Saltzman, Hong Shen, Janet L. Brandsma Second Edition Totowa, NJ Humana Press 2006 1 Online-Ressource (XVI, 384 p. 61 illus) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Medicine™ 127 In the early 1990s, almost 200 yr after Edward Jenner demonstrated the effectiveness of the smallpox vaccine, a new paradigm for vaccination emerged. The conventional method of vaccination required delivery of whole pathogens or structural subunits, but in this new approach, DNA or genetic information was administered to elicit an immunological response. Once it was observed that plasmid DNA delivered in vivo led to production of an encoded transgene (1), two ground-breaking studies demonstrated that immunological responses could be generated against antigenic transgenes via plasmid DNA delivered by DNA vaccination (as this approach is called) (2,3). The appe- ance of this new vaccination strategy coincided with advances in molecular biology, which provided new tools to study and manipulate the basic elements of an organism’s genome and also could also be applied to the design and production of DNA vaccines. DNA Vaccines is a major updated and enhancement of the first edition. It reviews state-of-the-art methods in DNA vaccine technology, with chapters describing DNA vaccine design, delivery systems, adjuvants, current appli- tions, methods of production, and quality control. Consistent with the approach of the Methods in Molecular Medicine series, these chapters contain detailed practical procedures on the latest DNA vaccine technology. The enthusiasm for DNA vaccine technology is made clear by the number of research studies published on this topic since the mid-1990s Biomedicine Immunology Medicine DNS (DE-588)4070512-2 gnd rswk-swf Impfstoff (DE-588)4026655-2 gnd rswk-swf DNS (DE-588)4070512-2 s Impfstoff (DE-588)4026655-2 s b DE-604 Saltzman, W. Mark edt Shen, Hong edt Brandsma, Janet L. edt Erscheint auch als Druck-Ausgabe 9781588294845 https://doi.org/10.1385/1597451681 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | DNA Vaccines Methods and Protocols Biomedicine Immunology Medicine DNS (DE-588)4070512-2 gnd Impfstoff (DE-588)4026655-2 gnd |
| subject_GND | (DE-588)4070512-2 (DE-588)4026655-2 |
| title | DNA Vaccines Methods and Protocols |
| title_auth | DNA Vaccines Methods and Protocols |
| title_exact_search | DNA Vaccines Methods and Protocols |
| title_full | DNA Vaccines Methods and Protocols edited by W. Mark Saltzman, Hong Shen, Janet L. Brandsma |
| title_fullStr | DNA Vaccines Methods and Protocols edited by W. Mark Saltzman, Hong Shen, Janet L. Brandsma |
| title_full_unstemmed | DNA Vaccines Methods and Protocols edited by W. Mark Saltzman, Hong Shen, Janet L. Brandsma |
| title_short | DNA Vaccines |
| title_sort | dna vaccines methods and protocols |
| title_sub | Methods and Protocols |
| topic | Biomedicine Immunology Medicine DNS (DE-588)4070512-2 gnd Impfstoff (DE-588)4026655-2 gnd |
| topic_facet | Biomedicine Immunology Medicine DNS Impfstoff |
| url | https://doi.org/10.1385/1597451681 |
| work_keys_str_mv | AT saltzmanwmark dnavaccinesmethodsandprotocols AT shenhong dnavaccinesmethodsandprotocols AT brandsmajanetl dnavaccinesmethodsandprotocols |