PTEN: Methods and Protocols
This volume provides detailed descriptions of prevailing and novel techniques used by experts in the study of PTEN function in disease and biology. The book begins with chapters exploring methods to detect expression levels of PTEN in normal and diseased human specimens; methods to evaluate specific...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer New York
2016
|
| Schriftenreihe: | Methods in Molecular Biology
1388 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | This volume provides detailed descriptions of prevailing and novel techniques used by experts in the study of PTEN function in disease and biology. The book begins with chapters exploring methods to detect expression levels of PTEN in normal and diseased human specimens; methods to evaluate specific PTEN function in brain cancer; methods that utilize a new biosensor to measure PTEN regulation; and techniques to measure post-transcriptional regulation of PTEN by micoRNAs and ceRNAs. Other chapters present methods describing novel techniques to detect PTEN localization and previously unstudied structural features of PTEN measured through X-Ray Crystallography and Hydrogen Deuterium Exchange Mass Spectrometry. The book concludes with methods to study PTEN function in model organisms including mice and C. elegans. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, PTEN: Methods and Protocols is a valuable collection of methodologies and protocols useful to researchers who are interested in the PTEN field |
| Beschreibung: | 1 Online-Ressource (XI, 324 p. 45 illus., 17 illus. in color) |
| ISBN: | 9781493932993 |
| DOI: | 10.1007/978-1-4939-3299-3 |
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Datensatz im Suchindex
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| dewey-full | 614.5999 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 614 - Forensic medicine; incidence of disease |
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| dewey-search | 614.5999 |
| dewey-sort | 3614.5999 |
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| discipline | Medizin |
| doi_str_mv | 10.1007/978-1-4939-3299-3 |
| format | Electronic eBook |
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| indexdate | 2024-07-10T08:05:36Z |
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| isbn | 9781493932993 |
| language | English |
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| physical | 1 Online-Ressource (XI, 324 p. 45 illus., 17 illus. in color) |
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| spelling | PTEN Methods and Protocols edited by Leonardo Salmena, Vuk Stambolic New York, NY Springer New York 2016 1 Online-Ressource (XI, 324 p. 45 illus., 17 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology 1388 This volume provides detailed descriptions of prevailing and novel techniques used by experts in the study of PTEN function in disease and biology. The book begins with chapters exploring methods to detect expression levels of PTEN in normal and diseased human specimens; methods to evaluate specific PTEN function in brain cancer; methods that utilize a new biosensor to measure PTEN regulation; and techniques to measure post-transcriptional regulation of PTEN by micoRNAs and ceRNAs. Other chapters present methods describing novel techniques to detect PTEN localization and previously unstudied structural features of PTEN measured through X-Ray Crystallography and Hydrogen Deuterium Exchange Mass Spectrometry. The book concludes with methods to study PTEN function in model organisms including mice and C. elegans. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, PTEN: Methods and Protocols is a valuable collection of methodologies and protocols useful to researchers who are interested in the PTEN field Biomedicine Cancer Research Human Genetics Medicine Cancer research Human genetics Salmena, Leonardo edt Stambolic, Vuk edt Erscheint auch als Druck-Ausgabe 9781493932979 https://doi.org/10.1007/978-1-4939-3299-3 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | PTEN Methods and Protocols Biomedicine Cancer Research Human Genetics Medicine Cancer research Human genetics |
| title | PTEN Methods and Protocols |
| title_auth | PTEN Methods and Protocols |
| title_exact_search | PTEN Methods and Protocols |
| title_full | PTEN Methods and Protocols edited by Leonardo Salmena, Vuk Stambolic |
| title_fullStr | PTEN Methods and Protocols edited by Leonardo Salmena, Vuk Stambolic |
| title_full_unstemmed | PTEN Methods and Protocols edited by Leonardo Salmena, Vuk Stambolic |
| title_short | PTEN |
| title_sort | pten methods and protocols |
| title_sub | Methods and Protocols |
| topic | Biomedicine Cancer Research Human Genetics Medicine Cancer research Human genetics |
| topic_facet | Biomedicine Cancer Research Human Genetics Medicine Cancer research Human genetics |
| url | https://doi.org/10.1007/978-1-4939-3299-3 |
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