RNA Interference: Challenges and Therapeutic Opportunities

RNA Interference: Challenges and Therapeutic Opportunities provides readers with recent advances in siRNA design, delivery, targeting, and methods to minimize siRNA’s unwanted effects. Preclinical and clinical use of synthetic siRNAs, the roles of miRNAs in cancer, and the promise of extracellular m...

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Bibliographic Details
Other Authors: Sioud, Mouldy (Editor)
Format: Electronic eBook
Language:English
Published: New York, NY Springer New York 2015
Series:Methods in Molecular Biology, Methods and Protocols 1218
Subjects:
Online Access:UBR01
TUM01
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Summary:RNA Interference: Challenges and Therapeutic Opportunities provides readers with recent advances in siRNA design, delivery, targeting, and methods to minimize siRNA’s unwanted effects. Preclinical and clinical use of synthetic siRNAs, the roles of miRNAs in cancer, and the promise of extracellular miRNAs for diagnosis are also covered in this meticulous collection, along with novel methods for identifying endogenous siRNAs and the annotation of small RNA transcriptomes. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.   Comprehensive and cutting-edge, RNA Interference: Challenges and Therapeutic Opportunities will aid researchers, clinicians, teachers, and biotechnologists interested in the power of RNA-based therapies
Physical Description:1 Online-Ressource (XVI, 495 p. 108 illus., 58 illus. in color)
ISBN:9781493915385
DOI:10.1007/978-1-4939-1538-5

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