RNA Interference: Challenges and Therapeutic Opportunities

RNA Interference: Challenges and Therapeutic Opportunities provides readers with recent advances in siRNA design, delivery, targeting, and methods to minimize siRNA’s unwanted effects. Preclinical and clinical use of synthetic siRNAs, the roles of miRNAs in cancer, and the promise of extracellular m...

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Bibliographische Detailangaben
Weitere Verfasser: Sioud, Mouldy (HerausgeberIn)
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: New York, NY Springer New York 2015
Schriftenreihe:Methods in Molecular Biology, Methods and Protocols 1218
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Zusammenfassung:RNA Interference: Challenges and Therapeutic Opportunities provides readers with recent advances in siRNA design, delivery, targeting, and methods to minimize siRNA’s unwanted effects. Preclinical and clinical use of synthetic siRNAs, the roles of miRNAs in cancer, and the promise of extracellular miRNAs for diagnosis are also covered in this meticulous collection, along with novel methods for identifying endogenous siRNAs and the annotation of small RNA transcriptomes. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.   Comprehensive and cutting-edge, RNA Interference: Challenges and Therapeutic Opportunities will aid researchers, clinicians, teachers, and biotechnologists interested in the power of RNA-based therapies
Beschreibung:1 Online-Ressource (XVI, 495 p. 108 illus., 58 illus. in color)
ISBN:9781493915385
DOI:10.1007/978-1-4939-1538-5

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