Mycobacterium tuberculosis Protocols:
With one-third of the world's population infected with Mycobacterium tuberculosis, over two million people a year dying from tuberculosis, and the appearance of multidrug-resistant strains, the need to understand the biology of M. tuberculosis, and so to develop new interventions, has become ac...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2001
|
| Schriftenreihe: | Methods in Molecular Medicine
54 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | With one-third of the world's population infected with Mycobacterium tuberculosis, over two million people a year dying from tuberculosis, and the appearance of multidrug-resistant strains, the need to understand the biology of M. tuberculosis, and so to develop new interventions, has become acute. In Mycobacterium tuberculosis Protocols, leading investigators with extensive practical knowledge and experience describe their best methods for studying this dangerous pathogen. Packed with step-by-step instructions to ensure successful results, these methods range from basic handling techniques to the application of functional genomics. These molecular techniques are suitable for research in genetics, biochemistry, microbiology, cell biology, epidemiology, and diagnostics, and are at the forefront of biological research as a whole, as well as in focused M. tuberculosis research. Highlights include methods for the basic safety and culture of M. tuberculosis, fractionation of the bacterium (nucleic acids, lipids, culture filtrate, and capsule), the analysis of gene expression (start-site mapping, real-time PCR, microarrays, and proteomics), the growth of the bacterium in macrophages and low oxygen, cytological analysis of the bacteria, and diagnostics. Highly practical and accessible, Mycobacterium tuberculosis Protocols utilizes advanced functional genomics and mutagenesis methodologies to provide both experimental and clinical investigators all the powerful techniques needed to illuminate the molecular biology of tuberculosis and its interactions with host cells, and so drive work on the wide variety of emerging therapeutic opportunities |
| Beschreibung: | 1 Online-Ressource (XIV, 406 p) |
| ISBN: | 9781592591473 |
| DOI: | 10.1385/1592591477 |
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| spelling | Mycobacterium tuberculosis Protocols edited by Tanya Parish, Neil G. Stoker Totowa, NJ Humana Press 2001 1 Online-Ressource (XIV, 406 p) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Medicine 54 With one-third of the world's population infected with Mycobacterium tuberculosis, over two million people a year dying from tuberculosis, and the appearance of multidrug-resistant strains, the need to understand the biology of M. tuberculosis, and so to develop new interventions, has become acute. In Mycobacterium tuberculosis Protocols, leading investigators with extensive practical knowledge and experience describe their best methods for studying this dangerous pathogen. Packed with step-by-step instructions to ensure successful results, these methods range from basic handling techniques to the application of functional genomics. These molecular techniques are suitable for research in genetics, biochemistry, microbiology, cell biology, epidemiology, and diagnostics, and are at the forefront of biological research as a whole, as well as in focused M. tuberculosis research. Highlights include methods for the basic safety and culture of M. tuberculosis, fractionation of the bacterium (nucleic acids, lipids, culture filtrate, and capsule), the analysis of gene expression (start-site mapping, real-time PCR, microarrays, and proteomics), the growth of the bacterium in macrophages and low oxygen, cytological analysis of the bacteria, and diagnostics. Highly practical and accessible, Mycobacterium tuberculosis Protocols utilizes advanced functional genomics and mutagenesis methodologies to provide both experimental and clinical investigators all the powerful techniques needed to illuminate the molecular biology of tuberculosis and its interactions with host cells, and so drive work on the wide variety of emerging therapeutic opportunities Medicine & Public Health Infectious Diseases Medicine Infectious diseases Tuberkelbakterium (DE-588)4186384-7 gnd rswk-swf Molekulare Medizin (DE-588)4543844-4 gnd rswk-swf Tuberkelbakterium (DE-588)4186384-7 s Molekulare Medizin (DE-588)4543844-4 s DE-604 Parish, Tanya edt Stoker, Neil G. edt Erscheint auch als Druck-Ausgabe 9780896037762 https://doi.org/10.1385/1592591477 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Mycobacterium tuberculosis Protocols Medicine & Public Health Infectious Diseases Medicine Infectious diseases Tuberkelbakterium (DE-588)4186384-7 gnd Molekulare Medizin (DE-588)4543844-4 gnd |
| subject_GND | (DE-588)4186384-7 (DE-588)4543844-4 |
| title | Mycobacterium tuberculosis Protocols |
| title_auth | Mycobacterium tuberculosis Protocols |
| title_exact_search | Mycobacterium tuberculosis Protocols |
| title_full | Mycobacterium tuberculosis Protocols edited by Tanya Parish, Neil G. Stoker |
| title_fullStr | Mycobacterium tuberculosis Protocols edited by Tanya Parish, Neil G. Stoker |
| title_full_unstemmed | Mycobacterium tuberculosis Protocols edited by Tanya Parish, Neil G. Stoker |
| title_short | Mycobacterium tuberculosis Protocols |
| title_sort | mycobacterium tuberculosis protocols |
| topic | Medicine & Public Health Infectious Diseases Medicine Infectious diseases Tuberkelbakterium (DE-588)4186384-7 gnd Molekulare Medizin (DE-588)4543844-4 gnd |
| topic_facet | Medicine & Public Health Infectious Diseases Medicine Infectious diseases Tuberkelbakterium Molekulare Medizin |
| url | https://doi.org/10.1385/1592591477 |
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