The Mitotic Exit Network: Methods and Protocols
This detailed book collects the main methodologies used for the analysis of the activity, localization, and regulation of the components of the Mitotic Exit Network (MEN) pathway during mitotic exit in Saccharomyces cerevisiae, as well as for the evaluation of the roles of these proteins in other ce...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer New York
2017
|
| Schriftenreihe: | Methods in Molecular Biology
1505 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | This detailed book collects the main methodologies used for the analysis of the activity, localization, and regulation of the components of the Mitotic Exit Network (MEN) pathway during mitotic exit in Saccharomyces cerevisiae, as well as for the evaluation of the roles of these proteins in other cellular processes, such as the condensation of the rDNA, the functionality of the mitotic checkpoints, and cytokinesis. Budding yeast serves as an ideal model system for dissecting the mechanisms that regulate cell cycle progression and providing new insights into the molecular basis of cell cycle control and, thus, into the origin of diseases that arise as a consequence of problems during cell division. Therefore, although this volume concentrates on Saccharomyces cerevisiae as a model, it also details the implications that the research about the MEN have on our understanding of the mitotic exit process in higher eukaryotes. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, The Mitotic Exit Network: Methods and Protocols will be a valuable reference for cellular and molecular biologists and biochemists as well as for all scientists interested in the study of the regulation of mitotic exit using budding yeast as a model organism |
| Beschreibung: | 1 Online-Ressource (X, 281 p. 35 illus., 24 illus. in color) |
| ISBN: | 9781493965021 |
| DOI: | 10.1007/978-1-4939-6502-1 |
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| discipline | Biologie |
| doi_str_mv | 10.1007/978-1-4939-6502-1 |
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| isbn | 9781493965021 |
| language | English |
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| spelling | The Mitotic Exit Network Methods and Protocols edited by Fernando Monje-Casas, Ethel Queralt New York, NY Springer New York 2017 1 Online-Ressource (X, 281 p. 35 illus., 24 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology 1505 This detailed book collects the main methodologies used for the analysis of the activity, localization, and regulation of the components of the Mitotic Exit Network (MEN) pathway during mitotic exit in Saccharomyces cerevisiae, as well as for the evaluation of the roles of these proteins in other cellular processes, such as the condensation of the rDNA, the functionality of the mitotic checkpoints, and cytokinesis. Budding yeast serves as an ideal model system for dissecting the mechanisms that regulate cell cycle progression and providing new insights into the molecular basis of cell cycle control and, thus, into the origin of diseases that arise as a consequence of problems during cell division. Therefore, although this volume concentrates on Saccharomyces cerevisiae as a model, it also details the implications that the research about the MEN have on our understanding of the mitotic exit process in higher eukaryotes. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, The Mitotic Exit Network: Methods and Protocols will be a valuable reference for cellular and molecular biologists and biochemists as well as for all scientists interested in the study of the regulation of mitotic exit using budding yeast as a model organism Life Sciences Cell Biology Life sciences Cell biology Monje-Casas, Fernando edt Queralt, Ethel edt Erscheint auch als Druck-Ausgabe 9781493965007 https://doi.org/10.1007/978-1-4939-6502-1 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | The Mitotic Exit Network Methods and Protocols Life Sciences Cell Biology Life sciences Cell biology |
| title | The Mitotic Exit Network Methods and Protocols |
| title_auth | The Mitotic Exit Network Methods and Protocols |
| title_exact_search | The Mitotic Exit Network Methods and Protocols |
| title_full | The Mitotic Exit Network Methods and Protocols edited by Fernando Monje-Casas, Ethel Queralt |
| title_fullStr | The Mitotic Exit Network Methods and Protocols edited by Fernando Monje-Casas, Ethel Queralt |
| title_full_unstemmed | The Mitotic Exit Network Methods and Protocols edited by Fernando Monje-Casas, Ethel Queralt |
| title_short | The Mitotic Exit Network |
| title_sort | the mitotic exit network methods and protocols |
| title_sub | Methods and Protocols |
| topic | Life Sciences Cell Biology Life sciences Cell biology |
| topic_facet | Life Sciences Cell Biology Life sciences Cell biology |
| url | https://doi.org/10.1007/978-1-4939-6502-1 |
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