Celiac Disease: Methods and Protocols
This volume provides detailed molecular analysis of the associated pathways and cell types involved in Celiac Disease, and embraces new technologies such as next generation sequencing. The book is divided into three parts: Part I gives a background overview with a number of reviews to describe the h...
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer New York
2015
|
| Ausgabe: | 1st ed. 2015 |
| Schriftenreihe: | Methods in Molecular Biology
1326 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | This volume provides detailed molecular analysis of the associated pathways and cell types involved in Celiac Disease, and embraces new technologies such as next generation sequencing. The book is divided into three parts: Part I gives a background overview with a number of reviews to describe the history and nature of the disease, its diagnosis, the role of animal models, and study designs for investigating genetic susceptibility. Part II describes molecular techniques, including tissue culture, isolation and cloning of relevant cell types, high content analysis of biopsies, and HLA genotyping. The final part of the book begins with an outline of scripting for data management, focusing on tools that are freely available to researchers who wish to explore them. It also describes analysis pipelines for bioinformatics prediction of antigenicity, quality control and analysis of GWAS data, and transcriptome analysis by next generation sequencing. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Celiac Disease: Methods and Protocols brings together novel and more traditional methods in molecular biology and immunology, in order to provide a tool-kit for all stages for Celiac Disease research—from the practicalities of identifying, obtaining, stabilizing and maintaining high quality samples, to molecular analysis and bioinformatics |
| Beschreibung: | 1 Online-Ressource (XI, 235 p. 39 illus., 30 illus. in color) |
| ISBN: | 9781493928392 |
| DOI: | 10.1007/978-1-4939-2839-2 |
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| dewey-full | 616.079 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
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| discipline | Medizin |
| doi_str_mv | 10.1007/978-1-4939-2839-2 |
| edition | 1st ed. 2015 |
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| indexdate | 2024-07-10T08:05:36Z |
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| isbn | 9781493928392 |
| language | English |
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| spelling | Celiac Disease Methods and Protocols edited by Anthony W. Ryan 1st ed. 2015 New York, NY Springer New York 2015 1 Online-Ressource (XI, 235 p. 39 illus., 30 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology 1326 This volume provides detailed molecular analysis of the associated pathways and cell types involved in Celiac Disease, and embraces new technologies such as next generation sequencing. The book is divided into three parts: Part I gives a background overview with a number of reviews to describe the history and nature of the disease, its diagnosis, the role of animal models, and study designs for investigating genetic susceptibility. Part II describes molecular techniques, including tissue culture, isolation and cloning of relevant cell types, high content analysis of biopsies, and HLA genotyping. The final part of the book begins with an outline of scripting for data management, focusing on tools that are freely available to researchers who wish to explore them. It also describes analysis pipelines for bioinformatics prediction of antigenicity, quality control and analysis of GWAS data, and transcriptome analysis by next generation sequencing. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Celiac Disease: Methods and Protocols brings together novel and more traditional methods in molecular biology and immunology, in order to provide a tool-kit for all stages for Celiac Disease research—from the practicalities of identifying, obtaining, stabilizing and maintaining high quality samples, to molecular analysis and bioinformatics Biomedicine Immunology Medicine Ryan, Anthony W. edt Erscheint auch als Druck-Ausgabe 9781493928385 https://doi.org/10.1007/978-1-4939-2839-2 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Celiac Disease Methods and Protocols Biomedicine Immunology Medicine |
| title | Celiac Disease Methods and Protocols |
| title_auth | Celiac Disease Methods and Protocols |
| title_exact_search | Celiac Disease Methods and Protocols |
| title_full | Celiac Disease Methods and Protocols edited by Anthony W. Ryan |
| title_fullStr | Celiac Disease Methods and Protocols edited by Anthony W. Ryan |
| title_full_unstemmed | Celiac Disease Methods and Protocols edited by Anthony W. Ryan |
| title_short | Celiac Disease |
| title_sort | celiac disease methods and protocols |
| title_sub | Methods and Protocols |
| topic | Biomedicine Immunology Medicine |
| topic_facet | Biomedicine Immunology Medicine |
| url | https://doi.org/10.1007/978-1-4939-2839-2 |
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