Vascular Disease: Molecular Biology and Gene Therapy Protocols
In Vascular Disease: Molecular Biology and Gene Therapy Protocols, Andrew Baker and a noted panel of expert investigators describe today's most powerful molecular methods for investigating the pathogenesis of vascular disease. These detailed, easy-to-follow techniques range from methods that ha...
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Weitere Verfasser: | |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Totowa, NJ
Humana Press
1999
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Schriftenreihe: | Methods in Molecular Medicine™
30 |
Schlagworte: | |
Online-Zugang: | UBR01 Volltext |
Zusammenfassung: | In Vascular Disease: Molecular Biology and Gene Therapy Protocols, Andrew Baker and a noted panel of expert investigators describe today's most powerful molecular methods for investigating the pathogenesis of vascular disease. These detailed, easy-to-follow techniques range from methods that have been used successfully to identify specific mutations involved in cardiovascular disorders, to those for transferring genes associated with cardiovascular disease into various vascular cell types by in vitro and in vivo routes. There are methods to identify novel genes and generate full-length cDNAs, to study gene transcription and promoter activity easily and effectively, and to ascertain precisely gene expression levels within the individual cell types in different pathophysiological conditions. Accurate methods to quantify apoptosis in both cultured cells and pathological specimens are also given. Vascular Disease: Molecular Biology and Gene Therapy Protocols offers today's vascular biologist and gene therapist an unprecedented ability to study the pathogenesis of vascular disease and readily to probe the potential for gene-based therapies. Powerful and productive, the techniques presented here operate across a wide range of exciting research areas, and promise spectacular therapeutic breakthroughs in the ongoing battle against vascular disease |
Beschreibung: | 1 Online-Ressource (XV, 441 p) |
ISBN: | 9781592592470 |
DOI: | 10.1385/1592592473 |
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520 | |a In Vascular Disease: Molecular Biology and Gene Therapy Protocols, Andrew Baker and a noted panel of expert investigators describe today's most powerful molecular methods for investigating the pathogenesis of vascular disease. These detailed, easy-to-follow techniques range from methods that have been used successfully to identify specific mutations involved in cardiovascular disorders, to those for transferring genes associated with cardiovascular disease into various vascular cell types by in vitro and in vivo routes. There are methods to identify novel genes and generate full-length cDNAs, to study gene transcription and promoter activity easily and effectively, and to ascertain precisely gene expression levels within the individual cell types in different pathophysiological conditions. Accurate methods to quantify apoptosis in both cultured cells and pathological specimens are also given. Vascular Disease: Molecular Biology and Gene Therapy Protocols offers today's vascular biologist and gene therapist an unprecedented ability to study the pathogenesis of vascular disease and readily to probe the potential for gene-based therapies. Powerful and productive, the techniques presented here operate across a wide range of exciting research areas, and promise spectacular therapeutic breakthroughs in the ongoing battle against vascular disease | ||
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Datensatz im Suchindex
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author2 | Baker, Andrew H. |
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indexdate | 2024-07-10T08:05:36Z |
institution | BVB |
isbn | 9781592592470 |
language | English |
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physical | 1 Online-Ressource (XV, 441 p) |
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publisher | Humana Press |
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spelling | Vascular Disease Molecular Biology and Gene Therapy Protocols edited by Andrew H. Baker Totowa, NJ Humana Press 1999 1 Online-Ressource (XV, 441 p) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Medicine™ 30 In Vascular Disease: Molecular Biology and Gene Therapy Protocols, Andrew Baker and a noted panel of expert investigators describe today's most powerful molecular methods for investigating the pathogenesis of vascular disease. These detailed, easy-to-follow techniques range from methods that have been used successfully to identify specific mutations involved in cardiovascular disorders, to those for transferring genes associated with cardiovascular disease into various vascular cell types by in vitro and in vivo routes. There are methods to identify novel genes and generate full-length cDNAs, to study gene transcription and promoter activity easily and effectively, and to ascertain precisely gene expression levels within the individual cell types in different pathophysiological conditions. Accurate methods to quantify apoptosis in both cultured cells and pathological specimens are also given. Vascular Disease: Molecular Biology and Gene Therapy Protocols offers today's vascular biologist and gene therapist an unprecedented ability to study the pathogenesis of vascular disease and readily to probe the potential for gene-based therapies. Powerful and productive, the techniques presented here operate across a wide range of exciting research areas, and promise spectacular therapeutic breakthroughs in the ongoing battle against vascular disease Medicine & Public Health Vascular Surgery Medicine Vascular surgery Baker, Andrew H. edt Erscheint auch als Druck-Ausgabe 9780896037311 https://doi.org/10.1385/1592592473 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Vascular Disease Molecular Biology and Gene Therapy Protocols Medicine & Public Health Vascular Surgery Medicine Vascular surgery |
title | Vascular Disease Molecular Biology and Gene Therapy Protocols |
title_auth | Vascular Disease Molecular Biology and Gene Therapy Protocols |
title_exact_search | Vascular Disease Molecular Biology and Gene Therapy Protocols |
title_full | Vascular Disease Molecular Biology and Gene Therapy Protocols edited by Andrew H. Baker |
title_fullStr | Vascular Disease Molecular Biology and Gene Therapy Protocols edited by Andrew H. Baker |
title_full_unstemmed | Vascular Disease Molecular Biology and Gene Therapy Protocols edited by Andrew H. Baker |
title_short | Vascular Disease |
title_sort | vascular disease molecular biology and gene therapy protocols |
title_sub | Molecular Biology and Gene Therapy Protocols |
topic | Medicine & Public Health Vascular Surgery Medicine Vascular surgery |
topic_facet | Medicine & Public Health Vascular Surgery Medicine Vascular surgery |
url | https://doi.org/10.1385/1592592473 |
work_keys_str_mv | AT bakerandrewh vasculardiseasemolecularbiologyandgenetherapyprotocols |