Peptide Modifications to Increase Metabolic Stability and Activity:
In Peptide Modifications to Increase Metabolic Stability and Activity, expert researchers in the field provide summarized methods for preparation, purification of modified peptides, and assessment of their biochemical activities. These methods and protocols include preparation of conformationally co...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2013
|
| Schriftenreihe: | Methods in Molecular Biology, Methods and Protocols
1081 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 Volltext |
| Zusammenfassung: | In Peptide Modifications to Increase Metabolic Stability and Activity, expert researchers in the field provide summarized methods for preparation, purification of modified peptides, and assessment of their biochemical activities. These methods and protocols include preparation of conformationally constrained peptides, modification of peptide bonds, introduction of nonproteinogenic amino acids, and alteration of peptides’ physical and biological properties by modification of the amino acid side chains and/or terminal residues. With additional chapter that describes new experimental approach for the detection of exogenous peptides within living cells using peptides labeled with heavy isotopes and confocal Raman microscopy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Peptide Modifications to Increase Metabolic Stability and Activity seeks to provide scientists with alternative approaches to peptide modification that many researchers may find applicable to their specific research requirements |
| Beschreibung: | 1 Online-Ressource (IX, 241 p. 92 illus., 16 illus. in color) |
| ISBN: | 9781627036528 |
| DOI: | 10.1007/978-1-62703-652-8 |
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| 520 | |a In Peptide Modifications to Increase Metabolic Stability and Activity, expert researchers in the field provide summarized methods for preparation, purification of modified peptides, and assessment of their biochemical activities. These methods and protocols include preparation of conformationally constrained peptides, modification of peptide bonds, introduction of nonproteinogenic amino acids, and alteration of peptides’ physical and biological properties by modification of the amino acid side chains and/or terminal residues. With additional chapter that describes new experimental approach for the detection of exogenous peptides within living cells using peptides labeled with heavy isotopes and confocal Raman microscopy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Peptide Modifications to Increase Metabolic Stability and Activity seeks to provide scientists with alternative approaches to peptide modification that many researchers may find applicable to their specific research requirements | ||
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| indexdate | 2024-07-10T08:05:36Z |
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| isbn | 9781627036528 |
| language | English |
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| spelling | Peptide Modifications to Increase Metabolic Stability and Activity edited by Predrag Cudic Totowa, NJ Humana Press 2013 1 Online-Ressource (IX, 241 p. 92 illus., 16 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology, Methods and Protocols 1081 In Peptide Modifications to Increase Metabolic Stability and Activity, expert researchers in the field provide summarized methods for preparation, purification of modified peptides, and assessment of their biochemical activities. These methods and protocols include preparation of conformationally constrained peptides, modification of peptide bonds, introduction of nonproteinogenic amino acids, and alteration of peptides’ physical and biological properties by modification of the amino acid side chains and/or terminal residues. With additional chapter that describes new experimental approach for the detection of exogenous peptides within living cells using peptides labeled with heavy isotopes and confocal Raman microscopy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Peptide Modifications to Increase Metabolic Stability and Activity seeks to provide scientists with alternative approaches to peptide modification that many researchers may find applicable to their specific research requirements Life Sciences Biochemistry, general Nucleic Acid Chemistry Life sciences Biochemistry Nucleic acids Stoffwechsel (DE-588)4057699-1 gnd rswk-swf Peptidderivate (DE-588)4380541-3 gnd rswk-swf Peptidderivate (DE-588)4380541-3 s Stoffwechsel (DE-588)4057699-1 s 1\p DE-604 Cudic, Predrag edt Erscheint auch als Druck-Ausgabe 9781627036511 https://doi.org/10.1007/978-1-62703-652-8 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Peptide Modifications to Increase Metabolic Stability and Activity Life Sciences Biochemistry, general Nucleic Acid Chemistry Life sciences Biochemistry Nucleic acids Stoffwechsel (DE-588)4057699-1 gnd Peptidderivate (DE-588)4380541-3 gnd |
| subject_GND | (DE-588)4057699-1 (DE-588)4380541-3 |
| title | Peptide Modifications to Increase Metabolic Stability and Activity |
| title_auth | Peptide Modifications to Increase Metabolic Stability and Activity |
| title_exact_search | Peptide Modifications to Increase Metabolic Stability and Activity |
| title_full | Peptide Modifications to Increase Metabolic Stability and Activity edited by Predrag Cudic |
| title_fullStr | Peptide Modifications to Increase Metabolic Stability and Activity edited by Predrag Cudic |
| title_full_unstemmed | Peptide Modifications to Increase Metabolic Stability and Activity edited by Predrag Cudic |
| title_short | Peptide Modifications to Increase Metabolic Stability and Activity |
| title_sort | peptide modifications to increase metabolic stability and activity |
| topic | Life Sciences Biochemistry, general Nucleic Acid Chemistry Life sciences Biochemistry Nucleic acids Stoffwechsel (DE-588)4057699-1 gnd Peptidderivate (DE-588)4380541-3 gnd |
| topic_facet | Life Sciences Biochemistry, general Nucleic Acid Chemistry Life sciences Biochemistry Nucleic acids Stoffwechsel Peptidderivate |
| url | https://doi.org/10.1007/978-1-62703-652-8 |
| work_keys_str_mv | AT cudicpredrag peptidemodificationstoincreasemetabolicstabilityandactivity |