Analysis of Psychiatric Drugs:
In this volume, we hope to cover the malor techniques that are presently being used to analyze the actions of drugs used in psyc- atry. The contributors of the chapters are active researchers who have considerable practical experience with the techniques they are describing, and the emphasis in the...
Gespeichert in:
| Weitere Verfasser: | , , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
1988
|
| Schriftenreihe: | Neuromethods
10 |
| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | In this volume, we hope to cover the malor techniques that are presently being used to analyze the actions of drugs used in psyc- atry. The contributors of the chapters are active researchers who have considerable practical experience with the techniques they are describing, and the emphasis in the chapters is on three types of psychiatric drugs, namely antidepressants, antipsychotics, and anxiolytics. The first chapter, by Curry and Yu, discusses protein binding of psychotropic drugs, with special reference to equilibrium ana- sis as the method of assessment and to lipophilicity correlations. Since many of the drugs used in treating psychiatric disorders are bound extensively to protein, this aspect is of great importance with regard to their therapeutic actions and toxicity, Basic mat- matical models, techniques for the study of protein binding, molecular aspects of protein binding, binding in relation to lipophilicity, indirect approaches to measurement of the fraction of drug bound, the function of protein binding, and tissue binding are among the topics discussed. Chapter 2, by Norman and B- rows, deals with the principles of isotope derivative assays and their applications to antidepressants and antipsychotics; extensive protocols are provided. The third chapter, by Cooper, deals with analysis by gas-liquid chromatography. Sample collection and storage, extraction procedures, column selection, use of internal standards, types of detectors, techniques of application, and - plications to specific drugs are among the topics discussed |
| Beschreibung: | 1 Online-Ressource (XX, 547 p) |
| ISBN: | 9781592596157 |
| DOI: | 10.1385/0896031217 |
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| 520 | |a In this volume, we hope to cover the malor techniques that are presently being used to analyze the actions of drugs used in psyc- atry. The contributors of the chapters are active researchers who have considerable practical experience with the techniques they are describing, and the emphasis in the chapters is on three types of psychiatric drugs, namely antidepressants, antipsychotics, and anxiolytics. The first chapter, by Curry and Yu, discusses protein binding of psychotropic drugs, with special reference to equilibrium ana- sis as the method of assessment and to lipophilicity correlations. Since many of the drugs used in treating psychiatric disorders are bound extensively to protein, this aspect is of great importance with regard to their therapeutic actions and toxicity, Basic mat- matical models, techniques for the study of protein binding, molecular aspects of protein binding, binding in relation to lipophilicity, indirect approaches to measurement of the fraction of drug bound, the function of protein binding, and tissue binding are among the topics discussed. Chapter 2, by Norman and B- rows, deals with the principles of isotope derivative assays and their applications to antidepressants and antipsychotics; extensive protocols are provided. The third chapter, by Cooper, deals with analysis by gas-liquid chromatography. Sample collection and storage, extraction procedures, column selection, use of internal standards, types of detectors, techniques of application, and - plications to specific drugs are among the topics discussed | ||
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Datensatz im Suchindex
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| spelling | Analysis of Psychiatric Drugs edited by Alan A. Boulton, Glen B. Baker, Ronald T. Coutts Totowa, NJ Humana Press 1988 1 Online-Ressource (XX, 547 p) txt rdacontent c rdamedia cr rdacarrier Neuromethods 10 In this volume, we hope to cover the malor techniques that are presently being used to analyze the actions of drugs used in psyc- atry. The contributors of the chapters are active researchers who have considerable practical experience with the techniques they are describing, and the emphasis in the chapters is on three types of psychiatric drugs, namely antidepressants, antipsychotics, and anxiolytics. The first chapter, by Curry and Yu, discusses protein binding of psychotropic drugs, with special reference to equilibrium ana- sis as the method of assessment and to lipophilicity correlations. Since many of the drugs used in treating psychiatric disorders are bound extensively to protein, this aspect is of great importance with regard to their therapeutic actions and toxicity, Basic mat- matical models, techniques for the study of protein binding, molecular aspects of protein binding, binding in relation to lipophilicity, indirect approaches to measurement of the fraction of drug bound, the function of protein binding, and tissue binding are among the topics discussed. Chapter 2, by Norman and B- rows, deals with the principles of isotope derivative assays and their applications to antidepressants and antipsychotics; extensive protocols are provided. The third chapter, by Cooper, deals with analysis by gas-liquid chromatography. Sample collection and storage, extraction procedures, column selection, use of internal standards, types of detectors, techniques of application, and - plications to specific drugs are among the topics discussed Biomedicine Neurosciences Medicine Psychiatrie (DE-588)4047667-4 gnd rswk-swf Arzneimittelanalyse (DE-588)4003116-0 gnd rswk-swf Psychopharmakon (DE-588)4047729-0 gnd rswk-swf Psychopharmakon (DE-588)4047729-0 s Arzneimittelanalyse (DE-588)4003116-0 s DE-604 Psychiatrie (DE-588)4047667-4 s Boulton, Alan A. edt Baker, Glen B. edt Coutts, Ronald T. edt Erscheint auch als Druck-Ausgabe 9780896031210 https://doi.org/10.1385/0896031217 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Analysis of Psychiatric Drugs Biomedicine Neurosciences Medicine Psychiatrie (DE-588)4047667-4 gnd Arzneimittelanalyse (DE-588)4003116-0 gnd Psychopharmakon (DE-588)4047729-0 gnd |
| subject_GND | (DE-588)4047667-4 (DE-588)4003116-0 (DE-588)4047729-0 |
| title | Analysis of Psychiatric Drugs |
| title_auth | Analysis of Psychiatric Drugs |
| title_exact_search | Analysis of Psychiatric Drugs |
| title_full | Analysis of Psychiatric Drugs edited by Alan A. Boulton, Glen B. Baker, Ronald T. Coutts |
| title_fullStr | Analysis of Psychiatric Drugs edited by Alan A. Boulton, Glen B. Baker, Ronald T. Coutts |
| title_full_unstemmed | Analysis of Psychiatric Drugs edited by Alan A. Boulton, Glen B. Baker, Ronald T. Coutts |
| title_short | Analysis of Psychiatric Drugs |
| title_sort | analysis of psychiatric drugs |
| topic | Biomedicine Neurosciences Medicine Psychiatrie (DE-588)4047667-4 gnd Arzneimittelanalyse (DE-588)4003116-0 gnd Psychopharmakon (DE-588)4047729-0 gnd |
| topic_facet | Biomedicine Neurosciences Medicine Psychiatrie Arzneimittelanalyse Psychopharmakon |
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