TGF-β Signaling: Methods and Protocols
This volume details up-to-date information and attempts to take the reader into the exciting realm of TGF-β from the basic principles to the practical applications. Chapters provide basic introduction of TGF-β signaling from the cell surface to the nucleus, methods and techniques for the investigati...
Gespeichert in:
| Weitere Verfasser: | , , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer New York
2016
|
| Ausgabe: | 1st ed. 2016 |
| Schriftenreihe: | Methods in Molecular Biology
1344 |
| Schlagworte: | |
| Online-Zugang: | UBR01 TUM01 URL des Erstveröffentlichers |
| Zusammenfassung: | This volume details up-to-date information and attempts to take the reader into the exciting realm of TGF-β from the basic principles to the practical applications. Chapters provide basic introduction of TGF-β signaling from the cell surface to the nucleus, methods and techniques for the investigation of TGF-β signaling mechanism including receptors, Smads, intracellular kinases, microRNA, epigenetic regulation, post-translational regulations, non-Smad pathway; the physiological implications including those in cell cycle arrest, epithelial-mesenchymal transition, endothelial cells, adipogenesis, Th differentiation, stem cell, bone remodeling, ovary, zebrofish development, and frog animal capping; and the methodologies including metastasis imaging, 3D morphogenesis, membrane receptor quantification, conditional knockout, bone remodeling, kinase and phosphatase assays, BiFC interaction assays, and genome-wide siRNA screen. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, TGF-Beta Signaling: Methods and Protocols aims to ensure successful results in the further study of this vital field |
| Beschreibung: | 1 Online-Ressource (XII, 394 p. 64 illus., 41 illus. in color) |
| ISBN: | 9781493929665 |
| DOI: | 10.1007/978-1-4939-2966-5 |
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| discipline | Biologie |
| doi_str_mv | 10.1007/978-1-4939-2966-5 |
| edition | 1st ed. 2016 |
| format | Electronic eBook |
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| spelling | TGF-β Signaling Methods and Protocols edited by Xin-Hua Feng, Pinglong Xu, Xia Lin 1st ed. 2016 New York, NY Springer New York 2016 1 Online-Ressource (XII, 394 p. 64 illus., 41 illus. in color) txt rdacontent c rdamedia cr rdacarrier Methods in Molecular Biology 1344 This volume details up-to-date information and attempts to take the reader into the exciting realm of TGF-β from the basic principles to the practical applications. Chapters provide basic introduction of TGF-β signaling from the cell surface to the nucleus, methods and techniques for the investigation of TGF-β signaling mechanism including receptors, Smads, intracellular kinases, microRNA, epigenetic regulation, post-translational regulations, non-Smad pathway; the physiological implications including those in cell cycle arrest, epithelial-mesenchymal transition, endothelial cells, adipogenesis, Th differentiation, stem cell, bone remodeling, ovary, zebrofish development, and frog animal capping; and the methodologies including metastasis imaging, 3D morphogenesis, membrane receptor quantification, conditional knockout, bone remodeling, kinase and phosphatase assays, BiFC interaction assays, and genome-wide siRNA screen. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, TGF-Beta Signaling: Methods and Protocols aims to ensure successful results in the further study of this vital field Life Sciences Cell Biology Life sciences Cell biology Feng, Xin-Hua edt Xu, Pinglong edt Lin, Xia edt Erscheint auch als Druck-Ausgabe 9781493929658 https://doi.org/10.1007/978-1-4939-2966-5 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | TGF-β Signaling Methods and Protocols Life Sciences Cell Biology Life sciences Cell biology |
| title | TGF-β Signaling Methods and Protocols |
| title_auth | TGF-β Signaling Methods and Protocols |
| title_exact_search | TGF-β Signaling Methods and Protocols |
| title_full | TGF-β Signaling Methods and Protocols edited by Xin-Hua Feng, Pinglong Xu, Xia Lin |
| title_fullStr | TGF-β Signaling Methods and Protocols edited by Xin-Hua Feng, Pinglong Xu, Xia Lin |
| title_full_unstemmed | TGF-β Signaling Methods and Protocols edited by Xin-Hua Feng, Pinglong Xu, Xia Lin |
| title_short | TGF-β Signaling |
| title_sort | tgf β signaling methods and protocols |
| title_sub | Methods and Protocols |
| topic | Life Sciences Cell Biology Life sciences Cell biology |
| topic_facet | Life Sciences Cell Biology Life sciences Cell biology |
| url | https://doi.org/10.1007/978-1-4939-2966-5 |
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